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https://www.readbyqxmd.com/read/27526146/effects-of-antioxidant-supplements-biopqq%C3%A2-on-cerebral-blood-flow-and-oxygen-metabolism-in-the-prefrontal-cortex
#1
RANDOMIZED CONTROLLED TRIAL
Masahiko Nakano, Yuta Murayama, Lizhen Hu, Kazuto Ikemoto, Tatsuo Uetake, Kaoru Sakatani
Pyrroloquinoline quinone (PQQ) is a quinone compound originally identified in methanol-utilizing bacteria and is a cofactor for redox enzymes. At the Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) 2014, we reported that PQQ disodium salt (BioPQQ™) improved cognitive function in humans, as assessed by the Stroop test. However, the physiological mechanism of PQQ remains unclear. In the present study, we measured regional cerebral blood flow (rCBF) and oxygen metabolism in prefrontal cortex (PFC), before and after administration of PQQ, using time-resolved near-infrared spectroscopy (tNIRS)...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28593105/photobiomodulation-with-near-infrared-light-helmet-in-a-pilot-placebo-controlled-clinical-trial-in-dementia-patients-testing-memory-and-cognition
#2
Marvin H Berman, James P Halper, Trent W Nichols, H Jarrett, Alan Lundy, Jason H Huang
Alzheimer's disease (AD) is a common, chronic expensive debilitating neurodegenerative disease with no current treatments to prevent the physical deterioration of the brain and the consequent cognitive deficits. The current pathophysiology of Alzheimer's disease is the accumulation of neurofibrillary tangles (NFTs) of hyperphosphorylated tau protein and amyloid-beta (Aβ) plaques. Antibody therapy of Tau and Amyloid beta, vaccines and other methods to decrease Tau and or Amyloid have not been successful after considerable pharmaceutical and biotech efforts...
2017: Journal of neurology and neuroscience
https://www.readbyqxmd.com/read/29057722/excessive-bodybuilding-as-pathology-a-first-neurophysiological-classification
#3
Moritz Julian Maier, Florian Benedikt Haeussinger, Martin Hautzinger, Andreas Jochen Fallgatter, Ann-Christine Ehlis
OBJECTIVES: Excessive Bodybuilding as a pathological syndrome has been classified based on two different theories: Bodybuilding as dependency or as muscle dysmorphic disorder (MDD). This study is a first attempt to find psychophysiological data supporting one of these classifications. METHODS: 24 participants (bodybuilders vs. healthy controls) were presented with pictures of bodies, exercise equipment or general reward stimuli in a control or experimental condition, and were measured with functional near-infrared spectroscopy (fNIRS)...
October 23, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29060419/physiological-fluctuations-show-frequency-specific-networks-in-fnirs-signals-during-resting-state
#4
Raul Fernandez Rojas, Xu Huang, Jesus Hernandez-Juarez, Keng-Liang Ou
Physiological fluctuations are commonly present in functional studies of hemodynamic response such as functional magnetic resonance imaging (fMRI) and functional near-infrared spectroscopy (fNIRS). However, the effects of these signals in neural mechanisms are not fully understood. Thus, the aim of this study is to propose that frequency-specific networks exist in the somatosensory region within the frequency range of physiological fluctuations. We used a wavelet coherence approach to identify functional connectivity between cortical regions...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060891/why-build-an-integrated-eeg-nirs-about-the-advantages-of-hybrid-bio-acquisition-hardware
#5
A von Luhmann, K-R Muller
OBJECTIVE: In medical applications, neuroscience and brain-computer interface research, bimodal acquisition of brain activity using Electroencephalography (EEG) and functional Near Infrared Spectroscopy (fNIRS) is at the moment achieved by combining separate commercial devices. We have investigated quantitatively whether dedicated hybrid systems exhibit more advantageous properties. METHODS: We studied intermodality electrical crosstalk and timing jitter in two separate and one hybrid EEG-NIRS acquisition device...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29066964/using-functional-near-infrared-spectroscopy-to-measure-effects-of-delta-9-tetrahydrocannabinol-on-prefrontal-activity-and-working-memory-in-cannabis-users
#6
Hasan O Keles, Milena Radoman, Gladys N Pachas, A Eden Evins, Jodi M Gilman
Intoxication from cannabis impairs cognitive performance, in part due to the effects of Δ9-tetrahydrocannabinol (THC, the primary psychoactive compound in cannabis) on prefrontal cortex (PFC) function. However, a relationship between impairment in cognitive functioning with THC administration and THC-induced change in hemodynamic response has not been demonstrated. We explored the feasibility of using functional near-infrared spectroscopy (fNIRS) to examine the functional changes of the human PFC associated with cannabis intoxication and cognitive impairment...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29060418/prefrontal-cortical-activation-while-viewing-urban-and-garden-scenes-a-pilot-fnirs-study
#7
Juanhong Yu, Kai Keng Ang, Su Hui Ho, Angelia Sia, Roger Ho
Recent studies have shown that pleasant and unpleasant emotions could be detected through functional Near-Infrared Spectroscopy (fNIRS). This study investigates the prefrontal cortical activation in human subjects while they were viewing urban and garden scenes. A multi-channel continuous wave fNIRS system was used to record the prefrontal cortical activations from seven subjects. During the data collection, the subjects viewed 40 trials of video clips. In each trial, the subjects viewed a video of randomized urban or garden scenes for 30s followed by 30s of idle scene which showed a dark blue progress bar on black background on the screen...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28994805/bouncing-ball-with-a-uniformly-varying-velocity-in-a-metronome-synchronization-task
#8
Yingyu Huang, Li Gu, Junkai Yang, Xiang Wu
Sensorimotor synchronization (SMS), a fundamental human ability to coordinate movements with external rhythms, has long been thought to be modality specific. In the canonical metronome synchronization task that requires tapping a finger along with an isochronous sequence, a well-established finding is that synchronization is much more stable to an auditory sequence consisting of auditory tones than to a visual sequence consisting of visual flashes. However, recent studies have shown that periodically moving visual stimuli can substantially improve synchronization compared with visual flashes...
September 21, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28925734/a-pilot-treatment-study-for-mild-traumatic-brain-injury-neuroimaging-changes-detected-by-meg-after-low-intensity-pulse-based-transcranial-electrical-stimulation
#9
Ming-Xiong Huang, Ashley Robb Swan, Annemarie Angeles Quinto, Scott Matthews, Deborah L Harrington, Sharon Nichols, Barry J Bruder, Corey C Snook, Charles W Huang, Dewleen G Baker, Roland R Lee
BACKGROUND: Mild traumatic brain injury (mTBI) is a leading cause of sustained impairments in military service members, Veterans, and civilians. However, few treatments are available for mTBI, partially because the mechanism of persistent mTBI deficits is not fully understood. METHODS: We used magnetoencephalography (MEG) to investigate neuronal changes in individuals with mTBI following a passive neurofeedback-based treatment programme called IASIS. This programme involved applying low-intensity pulses using transcranial electrical stimulation (LIP-tES) with electroencephalography monitoring...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28971410/eeg-analysis-of-the-neurofeedback-training-effect-in-algorithmic-thinking
#10
Antonia Plerou, Panayiotis Vlamos, Aikaterini Margetaki
Although significant advances have been made in understanding several cognitive states, the algorithmic thinking ability is yet to be analyzed in terms of neuroscience and brain imaging techniques. Studies on the effects of neurofeedback on learning disabilities especially mathematics disorders are limited. The objective of the present study is to evaluate the brain activity and activation differences between neurofeedback trained participants and controls, during the overall EEG analysis during continuous algorithmic tasks performance...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29021168/functional-ultrasound-imaging-of-brain-activity-in-human-newborns
#11
Charlie Demene, Jérome Baranger, Miguel Bernal, Catherine Delanoe, Stéphane Auvin, Valérie Biran, Marianne Alison, Jérome Mairesse, Elisabeth Harribaud, Mathieu Pernot, Mickael Tanter, Olivier Baud
Functional neuroimaging modalities are crucial for understanding brain function, but their clinical use is challenging. Recently, the use of ultrasonic plane waves transmitted at ultrafast frame rates was shown to allow for the spatiotemporal identification of brain activation through neurovascular coupling in rodents. Using a customized flexible and noninvasive headmount, we demonstrate in human neonates that real-time functional ultrasound imaging (fUSI) is feasible by combining simultaneous continuous video-electroencephalography (EEG) recording and ultrafast Doppler (UfD) imaging of the brain microvasculature...
October 11, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/29028805/what-drives-slow-wave-activity-during-early-non-rem-sleep-learning-during-prior-wake-or-effort
#12
Ziyang Li, Aarohi B Sheth, Bhavin R Sheth
What is the function of sleep in humans? One claim is that sleep consolidates learning. Slow wave activity (SWA), i.e. slow oscillations of frequency < 4 Hz, has been observed in electroencephalograms (EEG) during sleep; it increases with prior wakefulness and decreases with sleep. Studies have claimed that increase in SWA in specific regions of the sleeping brain is correlated with overnight improved performance, i.e. overnight consolidation, on a demanding motor learning task. We wondered if SWA change during sleep is attributable to overnight consolidation or to metabolic demand...
2017: PloS One
https://www.readbyqxmd.com/read/28779924/effect-of-essential-oil-and-supercritical-carbon-dioxide-extract-from-the-root-of-angelica-gigas-on-human-eeg-activity
#13
Kandhasamy Sowndhararajan, Min Seo, Minju Kim, Heeyeon Kim, Songmun Kim
OBJECTIVES: The present study aimed to investigate the effect of inhalation of essential oil (EO) and supercritical carbon dioxide extract (SC-CO2) from the root of A. gigas on human electroencephalographic (EEG) activity. MATERIALS AND METHODS: For this purpose, the EO was obtained from the root of A. gigas by steam distillation and SC-CO2 was obtained at 50 °C and 400 bar for 1 h. The EEG readings were recorded using the QEEG-8 system from 8 electrode sites according to the International 10-20 system...
August 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/26927928/psychophysiological-responses-to-auditory-change
#14
Lorraine Chuen, David Sears, Stephen McAdams
A comprehensive characterization of autonomic and somatic responding within the auditory domain is currently lacking. We studied whether simple types of auditory change that occur frequently during music listening could elicit measurable changes in heart rate, skin conductance, respiration rate, and facial motor activity. Participants heard a rhythmically isochronous sequence consisting of a repeated standard tone, followed by a repeated target tone that changed in pitch, timbre, duration, intensity, or tempo, or that deviated momentarily from rhythmic isochrony...
June 2016: Psychophysiology
https://www.readbyqxmd.com/read/26948160/brain-mechanisms-that-underlie-the-effects-of-motivational-audiovisual-stimuli-on-psychophysiological-responses-during-exercise
#15
Marcelo Bigliassi, Vinícius B Silva, Costas I Karageorghis, Jonathan M Bird, Priscila C Santos, Leandro R Altimari
Motivational audiovisual stimuli such as music and video have been widely used in the realm of exercise and sport as a means by which to increase situational motivation and enhance performance. The present study addressed the mechanisms that underlie the effects of motivational stimuli on psychophysiological responses and exercise performance. Twenty-two participants completed fatiguing isometric handgrip-squeezing tasks under two experimental conditions (motivational audiovisual condition and neutral audiovisual condition) and a control condition...
May 1, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/25928684/brain-oscillations-hypnosis-and-hypnotizability
#16
REVIEW
Mark P Jensen, Tomonori Adachi, Shahin Hakimian
This article summarizes the state-of-science knowledge regarding the associations between hypnosis and brain oscillations. Brain oscillations represent the combined electrical activity of neuronal assemblies, usually measured as specific frequencies representing slower (delta, theta, alpha) and faster (beta, gamma) oscillations. Hypnosis has been most closely linked to power in the theta band and changes in gamma activity. These oscillations are thought to play a critical role in both the recording and recall of declarative memory and emotional limbic circuits...
January 2015: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/24966381/gamma-deficits-as-a-neural-signature-of-cognitive-impairment-in-children-treated-for-brain-tumors
#17
Colleen Dockstader, Frank Wang, Eric Bouffet, Donald J Mabbott
Cognitive impairment is consistently reported in children treated for brain tumors, particularly in the categories of processing speed, memory, and attention. Although tumor site, hydrocephalus, chemotherapy, and cranial radiation therapy (CRT) are all associated with poorer function, CRT predicts the greatest deficits. There is a particularly high correlation between CRT and slowed information-processing speed. Cortical gamma-band oscillations have been associated with processing behaviorally relevant information; however, their role in the maintenance of cognition in individuals with processing deficits is unclear...
June 25, 2014: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/24816141/induction-of-self-awareness-in-dreams-through-frontal-low-current-stimulation-of-gamma-activity
#18
RANDOMIZED CONTROLLED TRIAL
Ursula Voss, Romain Holzmann, Allan Hobson, Walter Paulus, Judith Koppehele-Gossel, Ansgar Klimke, Michael A Nitsche
Recent findings link fronto-temporal gamma electroencephalographic (EEG) activity to conscious awareness in dreams, but a causal relationship has not yet been established. We found that current stimulation in the lower gamma band during REM sleep influences ongoing brain activity and induces self-reflective awareness in dreams. Other stimulation frequencies were not effective, suggesting that higher order consciousness is indeed related to synchronous oscillations around 25 and 40 Hz.
June 2014: Nature Neuroscience
https://www.readbyqxmd.com/read/24211625/better-than-sleep-theta-neurofeedback-training-accelerates-memory-consolidation
#19
Miriam Reiner, Roman Rozengurt, Anat Barnea
Consistent empirical results showed that both night and day sleep enhanced memory consolidation. In this study we explore processes of consolidation of memory during awake hours. Since theta oscillations have been shown to play a central role in exchange of information, we hypothesized that elevated theta during awake hours will enhance memory consolidation. We used a neurofeedback protocol, to enhance the relative power of theta or beta oscillations. Participants trained on a tapping task, were divided into three groups: neurofeedback theta; neurofeedback beta; control...
January 2014: Biological Psychology
https://www.readbyqxmd.com/read/24185428/temporal-synchrony-and-gamma-to-theta-power-conversion-in-the-dendrites-of-ca1-pyramidal-neurons
#20
Sachin P Vaidya, Daniel Johnston
Timing is a crucial aspect of synaptic integration. For pyramidal neurons that integrate thousands of synaptic inputs spread across hundreds of microns, it is thus a challenge to maintain the timing of incoming inputs at the axo-somatic integration site. Here we show that pyramidal neurons in the rodent hippocampus use a gradient of inductance in the form of hyperpolarization-activated cation-nonselective (HCN) channels as an active mechanism to counteract location-dependent temporal differences of dendritic inputs at the soma...
December 2013: Nature Neuroscience
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