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32 papers 0 to 25 followers
https://www.readbyqxmd.com/read/29741177/a-high-performance-sc-based-nanoprobe-for-through-skull-fluorescence-imaging-of-brain-vessels-beyond-1500-nm
#1
Zhiming Deng, Xiaolong Li, Zhenluan Xue, Mingyang Jiang, Youbin Li, Songjun Zeng, Hongrong Liu
Optical bioimaging that works in the second near infrared region (NIR-II, 1000-1700 nm) has emerged as a next generation imaging technique with superior imaging sensitivity and spatial resolution compared to traditional optical imaging utilizing visible and near-infrared lights (below 900 nm). Herein, a new Sc-based NIR-II probe was explored for high performance NIR-II in vivo bioimaging and optical imaging-guided non-invasive brain blood vessel visualization. The lanthanide doped Sc-based probes (KSc2F7:Yb3+/Er3+) possess a pure orthorhombic phase structure with size control by adjusting the F- ion content...
May 9, 2018: Nanoscale
https://www.readbyqxmd.com/read/29185494/performance-enhancement-of-a-brain-computer-interface-using-high-density-multi-distance-nirs
#2
Jaeyoung Shin, Jinuk Kwon, Jongkwan Choi, Chang-Hwan Im
This study investigated the effectiveness of using a high-density multi-distance source-detector (SD) separations in near-infrared spectroscopy (NIRS), for enhancing the performance of a functional NIRS (fNIRS)-based brain-computer interface (BCI). The NIRS system that was used for the experiment was capable of measuring signals from four SD separations: 15, 21.2, 30, and 33.5 mm, and this allowed the measurement of hemodynamic response alterations at various depths. Fifteen participants were asked to perform mental arithmetic and word chain tasks, to induce task-related hemodynamic response variations, or they were asked to stay relaxed to acquire a baseline signal...
November 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28980210/photobiomodulation-therapy-improves-acute-inflammatory-response-in-mice-the-role-of-cannabinoid-receptors-atp-sensitive-k-channel-p38-mapk-signalling-pathway
#3
Laís M S Neves, Elaine C D Gonçalves, Juliana Cavalli, Graziela Vieira, Larissa R Laurindo, Róli R Simões, Igor S Coelho, Adair R S Santos, Alexandre M Marcolino, Maíra Cola, Rafael C Dutra
Although photobiomodulation therapy (PBM) has been applied clinically for the treatment of pain and inflammation, wound healing, sports and soft tissue injuries, as well as to repair injured spinal cords and peripheral nerves, it remains unclear which molecular substrates (receptor) are implicated in the cellular mechanisms of PBM. Here, we reported that PBM (660 nm, 30 mW, 0.06 cm2, 50 J/cm2, plantar irradiation) significantly inhibited carrageenan-induced paw oedema, but not noxious thermal response, through positive modulation to both CB1 and CB2 cannabinoid receptors...
October 4, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/29131826/an-interactive-sports-video-game-as-an-intervention-for-rehabilitation-of-community-living-patients-with-schizophrenia-a-controlled-single-blind-crossover-study
#4
Nobuko Shimizu, Tomohiro Umemura, Masahiro Matsunaga, Takayoshi Hirai
Hypofrontality is a state of decreased cerebral blood flow in the prefrontal cortex during executive function performance; it is commonly observed in patients with schizophrenia. Cognitive dysfunction, as well as the psychological symptoms of schizophrenia, influences the ability of patients to reintegrate into society. The current study investigated the effects of an interactive sports video game (IVG; Nintendo Wii™ Sports Resort) on frontal lobe function of patients with schizophrenia. A sample of eight patients (6 male and 2 female; mean age = 46...
2017: PloS One
https://www.readbyqxmd.com/read/29163083/effective-connectivity-analysis-of-the-brain-network-in-drivers-during-actual-driving-using-near-infrared-spectroscopy
#5
Zhian Liu, Ming Zhang, Gongcheng Xu, Congcong Huo, Qitao Tan, Zengyong Li, Quan Yuan
Driving a vehicle is a complex activity that requires high-level brain functions. This study aimed to assess the change in effective connectivity (EC) between the prefrontal cortex (PFC), motor-related areas (MA) and vision-related areas (VA) in the brain network among the resting, simple-driving and car-following states. Twelve young male right-handed adults were recruited to participate in an actual driving experiment. The brain delta [HbO2 ] signals were continuously recorded using functional near infrared spectroscopy (fNIRS) instruments...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29049332/blue-lighting-accelerates-post-stress-relaxation-results-of-a-preliminary-study
#6
Jesus Minguillon, Miguel Angel Lopez-Gordo, Diego A Renedo-Criado, Maria Jose Sanchez-Carrion, Francisco Pelayo
Several authors have studied the influence of light on both human physiology and emotions. Blue light has been proved to reduce sleepiness by suppression of melatonin secretion and it is also present in many emotion-related studies. Most of these have a common lack of objective methodology since results and conclusions are based on subjective perception of emotions. The aim of this work was the objective assessment of the effect of blue lighting in post-stress relaxation, in comparison with white lighting, by means of bio-signals and standardized procedures...
2017: PloS One
https://www.readbyqxmd.com/read/29153344/sex-differences-in-humor-processing-an-event-related-potential-study
#7
Yi-Tzu Chang, Li-Chuan Ku, Hsueh-Chih Chen
Numerous behavioral studies and a handful of functional neuroimaging studies have reported sex differences in humor. However, no study to date has examined differences in the time-course of brain activity during multistage humor processing between the sexes. The purpose of this study was to compare real-time dynamics related to humor processing between women and men, with reference to a proposed three-stage model (involving incongruity detection, incongruity resolution, and elaboration stages). Forty undergraduate students (20 women) underwent event-related potential recording while subjectively rating 30 question-answer-type jokes and 30 question-answer-type statements in a random order...
February 2018: Brain and Cognition
https://www.readbyqxmd.com/read/29168791/administration-of-protocatechuic-acid-reduces-traumatic-brain-injury-induced-neuronal-death
#8
Sang Hwon Lee, Bo Young Choi, Song Hee Lee, A Ra Kho, Jeong Hyun Jeong, Dae Ki Hong, Sang Won Suh
Protocatechuic acid (PCA) was first purified from green tea and has shown numerous biological activities, including anti-apoptotic, anti-inflammatory, and anti-atherosclerotic effects. The effect of PCA on traumatic brain injury (TBI)-induced neuronal death has not previously been evaluated. TBI is defined as damage to the brain resulting from external mechanical force, such as rapid acceleration or deceleration, impact, blast waves, or penetration by a projectile. TBI causes neuronal death in the hippocampus and cerebral cortex...
November 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27526146/effects-of-antioxidant-supplements-biopqq%C3%A2-on-cerebral-blood-flow-and-oxygen-metabolism-in-the-prefrontal-cortex
#9
RANDOMIZED CONTROLLED TRIAL
Masahiko Nakano, Yuta Murayama, Lizhen Hu, Kazuto Ikemoto, Tatsuo Uetake, Kaoru Sakatani
Pyrroloquinoline quinone (PQQ) is a quinone compound originally identified in methanol-utilizing bacteria and is a cofactor for redox enzymes. At the Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) 2014, we reported that PQQ disodium salt (BioPQQ™) improved cognitive function in humans, as assessed by the Stroop test. However, the physiological mechanism of PQQ remains unclear. In the present study, we measured regional cerebral blood flow (rCBF) and oxygen metabolism in prefrontal cortex (PFC), before and after administration of PQQ, using time-resolved near-infrared spectroscopy (tNIRS)...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28593105/photobiomodulation-with-near-infrared-light-helmet-in-a-pilot-placebo-controlled-clinical-trial-in-dementia-patients-testing-memory-and-cognition
#10
Marvin H Berman, James P Halper, Trent W Nichols, H Jarrett, Alan Lundy, Jason H Huang
Alzheimer's disease (AD) is a common, chronic expensive debilitating neurodegenerative disease with no current treatments to prevent the physical deterioration of the brain and the consequent cognitive deficits. The current pathophysiology of Alzheimer's disease is the accumulation of neurofibrillary tangles (NFTs) of hyperphosphorylated tau protein and amyloid-beta (Aβ) plaques. Antibody therapy of Tau and Amyloid beta, vaccines and other methods to decrease Tau and or Amyloid have not been successful after considerable pharmaceutical and biotech efforts...
2017: Journal of neurology and neuroscience
https://www.readbyqxmd.com/read/29057722/excessive-bodybuilding-as-pathology-a-first-neurophysiological-classification
#11
Moritz Julian Maier, Florian Benedikt Haeussinger, Martin Hautzinger, Andreas Jochen Fallgatter, Ann-Christine Ehlis
OBJECTIVES: Excessive bodybuilding as a pathological syndrome has been classified based on two different theories: bodybuilding as dependency or as muscle dysmorphic disorder (MDD). This study is a first attempt to find psychophysiological data supporting one of these classifications. METHODS: Twenty-four participants (bodybuilders vs healthy controls) were presented with pictures of bodies, exercise equipment or general reward stimuli in a control or experimental condition, and were measured with functional near-infrared spectroscopy (fNIRS)...
November 15, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29060419/physiological-fluctuations-show-frequency-specific-networks-in-fnirs-signals-during-resting-state
#12
Raul Fernandez Rojas, Xu Huang, Jesus Hernandez-Juarez, Keng-Liang Ou
Physiological fluctuations are commonly present in functional studies of hemodynamic response such as functional magnetic resonance imaging (fMRI) and functional near-infrared spectroscopy (fNIRS). However, the effects of these signals in neural mechanisms are not fully understood. Thus, the aim of this study is to propose that frequency-specific networks exist in the somatosensory region within the frequency range of physiological fluctuations. We used a wavelet coherence approach to identify functional connectivity between cortical regions...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060891/why-build-an-integrated-eeg-nirs-about-the-advantages-of-hybrid-bio-acquisition-hardware
#13
A von Luhmann, K-R Muller
OBJECTIVE: In medical applications, neuroscience and brain-computer interface research, bimodal acquisition of brain activity using Electroencephalography (EEG) and functional Near Infrared Spectroscopy (fNIRS) is at the moment achieved by combining separate commercial devices. We have investigated quantitatively whether dedicated hybrid systems exhibit more advantageous properties. METHODS: We studied intermodality electrical crosstalk and timing jitter in two separate and one hybrid EEG-NIRS acquisition device...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29066964/using-functional-near-infrared-spectroscopy-to-measure-effects-of-delta-9-tetrahydrocannabinol-on-prefrontal-activity-and-working-memory-in-cannabis-users
#14
Hasan O Keles, Milena Radoman, Gladys N Pachas, A Eden Evins, Jodi M Gilman
Intoxication from cannabis impairs cognitive performance, in part due to the effects of Δ9-tetrahydrocannabinol (THC, the primary psychoactive compound in cannabis) on prefrontal cortex (PFC) function. However, a relationship between impairment in cognitive functioning with THC administration and THC-induced change in hemodynamic response has not been demonstrated. We explored the feasibility of using functional near-infrared spectroscopy (fNIRS) to examine the functional changes of the human PFC associated with cannabis intoxication and cognitive impairment...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29060418/prefrontal-cortical-activation-while-viewing-urban-and-garden-scenes-a-pilot-fnirs-study
#15
Juanhong Yu, Kai Keng Ang, Su Hui Ho, Angelia Sia, Roger Ho
Recent studies have shown that pleasant and unpleasant emotions could be detected through functional Near-Infrared Spectroscopy (fNIRS). This study investigates the prefrontal cortical activation in human subjects while they were viewing urban and garden scenes. A multi-channel continuous wave fNIRS system was used to record the prefrontal cortical activations from seven subjects. During the data collection, the subjects viewed 40 trials of video clips. In each trial, the subjects viewed a video of randomized urban or garden scenes for 30s followed by 30s of idle scene which showed a dark blue progress bar on black background on the screen...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28994805/bouncing-ball-with-a-uniformly-varying-velocity-in-a-metronome-synchronization-task
#16
Yingyu Huang, Li Gu, Junkai Yang, Xiang Wu
Sensorimotor synchronization (SMS), a fundamental human ability to coordinate movements with external rhythms, has long been thought to be modality specific. In the canonical metronome synchronization task that requires tapping a finger along with an isochronous sequence, a well-established finding is that synchronization is much more stable to an auditory sequence consisting of auditory tones than to a visual sequence consisting of visual flashes. However, recent studies have shown that periodically moving visual stimuli can substantially improve synchronization compared with visual flashes...
September 21, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28925734/a-pilot-treatment-study-for-mild-traumatic-brain-injury-neuroimaging-changes-detected-by-meg-after-low-intensity-pulse-based-transcranial-electrical-stimulation
#17
Ming-Xiong Huang, Ashley Robb Swan, Annemarie Angeles Quinto, Scott Matthews, Deborah L Harrington, Sharon Nichols, Barry J Bruder, Corey C Snook, Charles W Huang, Dewleen G Baker, Roland R Lee
BACKGROUND: Mild traumatic brain injury (mTBI) is a leading cause of sustained impairments in military service members, Veterans, and civilians. However, few treatments are available for mTBI, partially because the mechanism of persistent mTBI deficits is not fully understood. METHODS: We used magnetoencephalography (MEG) to investigate neuronal changes in individuals with mTBI following a passive neurofeedback-based treatment programme called IASIS. This programme involved applying low-intensity pulses using transcranial electrical stimulation (LIP-tES) with electroencephalography monitoring...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28971410/eeg-analysis-of-the-neurofeedback-training-effect-in-algorithmic-thinking
#18
Antonia Plerou, Panayiotis Vlamos, Aikaterini Margetaki
Although significant advances have been made in understanding several cognitive states, the algorithmic thinking ability is yet to be analyzed in terms of neuroscience and brain imaging techniques. Studies on the effects of neurofeedback on learning disabilities especially mathematics disorders are limited. The objective of the present study is to evaluate the brain activity and activation differences between neurofeedback trained participants and controls, during the overall EEG analysis during continuous algorithmic tasks performance...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29021168/functional-ultrasound-imaging-of-brain-activity-in-human-newborns
#19
Charlie Demene, Jérome Baranger, Miguel Bernal, Catherine Delanoe, Stéphane Auvin, Valérie Biran, Marianne Alison, Jérome Mairesse, Elisabeth Harribaud, Mathieu Pernot, Mickael Tanter, Olivier Baud
Functional neuroimaging modalities are crucial for understanding brain function, but their clinical use is challenging. Recently, the use of ultrasonic plane waves transmitted at ultrafast frame rates was shown to allow for the spatiotemporal identification of brain activation through neurovascular coupling in rodents. Using a customized flexible and noninvasive headmount, we demonstrate in human neonates that real-time functional ultrasound imaging (fUSI) is feasible by combining simultaneous continuous video-electroencephalography (EEG) recording and ultrafast Doppler (UfD) imaging of the brain microvasculature...
October 11, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/29028805/what-drives-slow-wave-activity-during-early-non-rem-sleep-learning-during-prior-wake-or-effort
#20
Ziyang Li, Aarohi B Sheth, Bhavin R Sheth
What is the function of sleep in humans? One claim is that sleep consolidates learning. Slow wave activity (SWA), i.e. slow oscillations of frequency < 4 Hz, has been observed in electroencephalograms (EEG) during sleep; it increases with prior wakefulness and decreases with sleep. Studies have claimed that increase in SWA in specific regions of the sleeping brain is correlated with overnight improved performance, i.e. overnight consolidation, on a demanding motor learning task. We wondered if SWA change during sleep is attributable to overnight consolidation or to metabolic demand...
2017: PloS One
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