Ian E McCoy, Jesse Y Hsu, Xiaoming Zhang, Clarissa J Diamantidis, Jonathan Taliercio, Alan S Go, Kathleen D Liu, Paul Drawz, Anand Srivastava, Edward J Horwitz, Jiang He, Jing Chen, James P Lash, Matthew R Weir, Chi-Yuan Hsu
BACKGROUND: Patients hospitalized with AKI have higher subsequent risks of heart failure, atherosclerotic cardiovascular events, and mortality than their counterparts without AKI, but these higher risks may be due to differences in prehospitalization patient characteristics, including the baseline level of estimated glomerular filtration rate (eGFR), the rate of prior eGFR decline, and the proteinuria level, rather than AKI itself. METHODS: Among 2177 adult participants in the Chronic Renal Insufficiency Cohort study who were hospitalized in 2013-2019, we compared subsequent risks of heart failure, atherosclerotic cardiovascular events, and mortality between those with serum creatinine-based AKI (495 patients) and those without AKI (1682 patients)...
April 28, 2023: Clinical Journal of the American Society of Nephrology: CJASN