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AKI Diagnosis

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3 papers 0 to 25 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
https://www.readbyqxmd.com/read/28167845/acute-kidney-injury-diagnostic-approaches-and-controversies
#1
REVIEW
Konstantinos Makris, Loukia Spanou
Acute kidney injury (AKI) is a significant independent risk factor for morbidity and mortality. In the last ten years a large number of publications have highlighted the limitations of traditional approaches and the inadequacies of conventional biomarkers to diagnose and monitor renal insufficiency in the acute setting. A great effort was directed not only to the discovery and validation of new biomarkers aimed to detect AKI more accurately but also to standardise the definition of AKI. Despite the advances in both areas, biomarkers have not yet entered into routine clinical practice and the definition of this syndrome has many areas of uncertainty...
December 2016: Clinical Biochemist. Reviews
https://www.readbyqxmd.com/read/26410133/diagnostic-criteria-for-acute-kidney-injury-present-and-future
#2
REVIEW
John A Kellum
Acute kidney injury (AKI) is a clinical diagnosis guided by standard criteria based on changes in serum creatinine, urine output, or both. Severity of AKI is determined by the magnitude of increase in serum creatinine or decrease in urine output. Patients manifesting both oliguria and azotemia and those in which these impairments are persistent are more likely to have worse disease and worse outcomes. Short- and long-term outcomes are worse when patients have some stage of AKI by both criteria. New biomarkers for AKI may substantially aid in the risk assessment and evaluation of patients at risk for AKI...
October 2015: Critical Care Clinics
https://www.readbyqxmd.com/read/26398357/assessment-of-fractional-excretion-of-urea-for-early-diagnosis-of-cardiac-surgery-associated-acute-kidney-injury
#3
Carlos Federico Varela, Gustavo Greloni, Carlos Schreck, Griselda Bratti, Angel Medina, Ricardo Marenchino, Rodolfo Pizarro, Cesar Belziti, Guillermo Rosa-Diez
BACKGROUND: Acute kidney injury (AKI) is a common complication after cardiac surgery (CS). Recently, neutrophil gelatinase-associated lipocalin (NGAL) was shown to predict AKI development earlier than serum creatinine, but it is not widely used in clinical practice. Fractional excretion of urea (FeU) has been referred to as a useful tool to discriminate between prerenal and established AKI. The aim of our study is to evaluate the sensitivity and specificity of FeU, in the early diagnosis of AKI in patients undergoing CS...
November 2015: Renal Failure
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