Use the collections feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Katherine N Weller, Fred H Hsieh
The practice parameter update on anaphylaxis from the Joint Task Force on Practice Parameters, with the collaboration of the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology, addresses key issues in the management and prevention of anaphylaxis. The updated guidelines define diagnostic criteria for anaphylaxis; therapeutic use of epinephrine, antihistamines, and glucocorticoids; prevention of recurrent anaphylaxis; and follow-up care that includes education on trigger avoidance and use of self-injectable epinephrine...
February 1, 2022: Cleveland Clinic Journal of Medicine
#22
REVIEW
Carlo Maria Rossi, Marco Vincenzo Lenti, Antonio Di Sabatino
Anaphylaxis is the most severe among acute allergic diseases and potentially life threatening. Despite its increasing frequency and related burden, it remains often underdiagnosed and improperly managed. Its multisystemic involvement, protean clinical manifestations and its rapid onset are contributory factors. In recent years new acquisitions have shed light into its pathogenesis pathways (and related biomarkers), triggers, factors increasing its severity, along with peculiar clinical manifestations. These breakthrough discoveries have contributed to phenotyping and endotyping this disease, possibly paving the way to a personalized approach which is not available at present...
June 2022: European Journal of Internal Medicine
#23
REVIEW
Kelly McHugh, Zachary Repanshek
Anaphylaxis is a potentially life-threatening, multisystem allergic reaction that can cause airway, breathing, or circulatory compromise. Intramuscular epinephrine is the immediate treatment of all patients. Intravenous epinephrine should be used in patients in shock, either as a bolus or infusion, along with fluid resuscitation. Airway obstruction must be recognized, and early intubation may be necessary. For shock that is refractory to epinephrine, additional vasopressors may be needed. Disposition depends on patient presentation and response to treatment...
February 2022: Emergency Medicine Clinics of North America
#24
REVIEW
Genevieve Schult Krajewski, Thomas Krajewski
Food allergies are a common and serious cause of illness, accounting for an increasing number of emergency department visits annually. Although definite diagnosis lays outside of an emergency department visit, the clinical management of the most serious food allergies highlights emergency care. The staple of acute care remains epinephrine in association with antihistamines and steroids. The greatest threat remains undertreatment for this group of disorders and underutilization of epinephrine. Those who have been treated for a food allergy need a follow-up allergist evaluation, guidance of food avoidance, and avoidance of foods with cross-sensitivities as well as ready access to epinephrine...
February 2022: Emergency Medicine Clinics of North America
#25
REVIEW
Leen Alblaihed, Maite Anna Huis In 't Veld
Acute coronary syndrome (ACS) in the setting of an allergic/immunologic reaction is known as Kounis syndrome. It is an underdiagnosed and underrecognized disease entity. One must keep a high index of suspicions when managing a patient presenting with cardiac as well as allergic symptoms. There are 3 main variants to the syndrome. Treating the allergic reaction may alleviate the pain; however, ACS guidelines should be followed if cardiac ischemia is present.
February 2022: Emergency Medicine Clinics of North America
#26
REVIEW
R Gentry Wilkerson, Michael E Winters
Angioedema is a well-recognized and potentially lethal complication of angiotensin-converting enzyme inhibitor (ACEi) therapy. In ACEi-induced angioedema, bradykinin accumulates due to a decrease in its metabolism by ACE, the enzyme that is primarily responsible for this function. The action of bradykinin at bradykinin type 2 receptors leads to increased vascular permeability and the accumulation of fluid in the subcutaneous and submucosal space. Patients with ACEi-induced angioedema are at risk for airway compromise because of the tendency for the face, lips, tongue, and airway structures to be affected...
February 2022: Emergency Medicine Clinics of North America
#27
REVIEW
R Gentry Wilkerson, Joseph J Moellman
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disorder that usual results from a decreased level of functional C1-INH and clinically manifests with intermittent attacks of swelling of the subcutaneous tissue or submucosal layers of the respiratory or gastrointestinal tracts. Laboratory studies and radiographic imaging have limited roles in evaluation of patients with acute attacks of HAE except when the diagnosis is uncertain and other processes must be ruled out. Treatment begins with assessment of the airway to determine the need for immediate intervention...
February 2022: Emergency Medicine Clinics of North America
#28
REVIEW
Lennart Nilsson, Ágnes Csuth, Jann Storsaeter, Lene H Garvey, Maria C Jenmalm
PURPOSE OF REVIEW: Whereas the COVID-19 pandemic has changed our lives worldwide, we hope that vaccination can combat the disease. We propose how to evaluate suspected severe allergic reactions to the vaccines so that as many as possible may be safely vaccinated. RECENT FINDINGS: Rare cases of severe allergic reactions after COVID-19 vaccination have been observed, seemingly at a higher frequency than for other vaccines. Few excipients are likely to have caused these reactions...
August 1, 2021: Current Opinion in Allergy and Clinical Immunology
#29
REVIEW
Jane C Y Wong, Philip H Li
PURPOSE OF REVIEW: Drug allergy management has previously not been emphasized in the elderly. However, the geriatric population poses several unique characteristics, challenges for drug allergy testing and considerations in the management. Especially in the era of COVID-19, the elderly population is a vulnerable cohort and reviewing the management during this unprecedented time is both timely and relevant. RECENT FINDINGS: In recent years, larger scale studies focusing on the epidemiology and prevalence trends of drug allergies among older adults has been summarized in this review...
August 1, 2021: Current Opinion in Allergy and Clinical Immunology
#30
REVIEW
Amy Dodd, Anna Hughes, Nicholas Sargant, Andrew F Whyte, Jasmeet Soar, Paul J Turner
The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis. As part of this process, an evidence review was undertaken by the Guideline Working Group, using an internationally-accepted approach for adoption, adaptation, and de novo guideline development based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) evidence to decision (EtD) framework, referred to as GRADE-ADOLOPMENT. A number of significant changes have been made, which will be reflected in the updated Guideline...
April 23, 2021: Resuscitation
#31
REVIEW
Luciana Kase Tanno, Pascal Demoly
PURPOSE OF REVIEW: To understand the current global epidemiological data of anaphylaxis and identify potential strategies to improve patients' care and prevention. RECENT FINDINGS: Anaphylaxis mortality and morbidity statistics (MMS) may gain new perspectives with the implementation of the International Classification of Diseases (ICD)-11 in the forthcoming years. Improving the quality of epidemiological data related to anaphylaxis should clarify some areas of uncertainty about risk factors, leading to better targeting of strategies to protect those patients at risk, and support decision-making to facilitate healthcare planning and implementation of public health measures to prevent anaphylaxis...
April 1, 2021: Current Opinion in Allergy and Clinical Immunology
#32
REVIEW
Claus Bachert, Bradley Marple, Rodney J Schlosser, Claire Hopkins, Robert P Schleimer, Bart N Lambrecht, Barbara M Bröker, Tanya Laidlaw, Woo-Jung Song
Chronic rhinosinusitis (CRS) occurs in >10% of the adult population in Europe and the USA and can be differentiated into CRS without nasal polyps and CRS with nasal polyps (CRSwNP). Both phenotypes are characterized by a high disease burden and an overlapping spectrum of symptoms, with facial pain and loss of smell being the most differentiating. Great progress has been made in the understanding of CRS pathophysiology: from the epithelium and epithelial-mesenchymal transition to innate and adaptive immunity pathways and, finally, on the role of eosinophils and Staphylococcus aureus in the persistence of disease...
October 29, 2020: Nature Reviews. Disease Primers
#33
REVIEW
Jean Bousquet, Josep M Anto, Claus Bachert, Ilaria Baiardini, Sinthia Bosnic-Anticevich, G Walter Canonica, Erik Melén, Oscar Palomares, Glenis K Scadding, Alkis Togias, Sanna Toppila-Salmi
Allergic rhinitis (AR) is caused by immunoglobulin E (IgE)-mediated reactions to inhaled allergens and is one of the most common chronic conditions globally. AR often co-occurs with asthma and conjunctivitis and is a global health problem causing major burden and disability worldwide. Risk factors include inhalant and occupational allergens, as well as genetic factors. AR impairs quality of life, affects social life, school and work, and is associated with substantial economic costs. The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative classified AR into intermittent or persistent and mild or moderate/severe...
December 3, 2020: Nature Reviews. Disease Primers
#34
JOURNAL ARTICLE
Victoria Cardona, Ignacio J Ansotegui, Motohiro Ebisawa, Yehia El-Gamal, Montserrat Fernandez Rivas, Stanley Fineman, Mario Geller, Alexei Gonzalez-Estrada, Paul A Greenberger, Mario Sanchez Borges, Gianenrico Senna, Aziz Sheikh, Luciana Kase Tanno, Bernard Y Thong, Paul J Turner, Margitta Worm
Anaphylaxis is the most severe clinical presentation of acute systemic allergic reactions. The occurrence of anaphylaxis has increased in recent years, and subsequently, there is a need to continue disseminating knowledge on the diagnosis and management, so every healthcare professional is prepared to deal with such emergencies. The rationale of this updated position document is the need to keep guidance aligned with the current state of the art of knowledge in anaphylaxis management. The World Allergy Organization (WAO) anaphylaxis guidelines were published in 2011, and the current guidance adopts their major indications, incorporating some novel changes...
October 2020: World Allergy Organization Journal
#35
REVIEW
Ana Dioun Broyles, Aleena Banerji, Sara Barmettler, Catherine M Biggs, Kimberly Blumenthal, Patrick J Brennan, Rebecca G Breslow, Knut Brockow, Kathleen M Buchheit, Katherine N Cahill, Josefina Cernadas, Anca Mirela Chiriac, Elena Crestani, Pascal Demoly, Pascale Dewachter, Meredith Dilley, Jocelyn R Farmer, Dinah Foer, Ari J Fried, Sarah L Garon, Matthew P Giannetti, David L Hepner, David I Hong, Joyce T Hsu, Parul H Kothari, Timothy Kyin, Timothy Lax, Min Jung Lee, Kathleen Lee-Sarwar, Anne Liu, Stephanie Logsdon, Margee Louisias, Andrew MacGinnitie, Michelle Maciag, Samantha Minnicozzi, Allison E Norton, Iris M Otani, Miguel Park, Sarita Patil, Elizabeth J Phillips, Matthieu Picard, Craig D Platt, Rima Rachid, Tito Rodriguez, Antonino Romano, Cosby A Stone, Maria Jose Torres, Miriam Verdú, Alberta L Wang, Paige Wickner, Anna R Wolfson, Johnson T Wong, Christina Yee, Joseph Zhou, Mariana Castells
No abstract text is available yet for this article.
October 2020: Journal of Allergy and Clinical Immunology in Practice
#36
MULTICENTER STUDY
Philippe Guerci, Charles Tacquard, Laura Chenard, David Millard, Lila Soufir, Jean-Marc Malinovsky, Matthias Garot, Jean-Marc Lalot, Guillaume Besch, Guillaume Louis, Laurie-Anne Thion, Claire Charpentier, Antoine Kimmoun, Marc Danguy Des Déserts, Serge Carreira, Gaetan Plantefeve, Emmanuel Novy, Paul Abraham, Paul-Michel Mertes
BACKGROUND: Few data are available on patients who have experienced anaphylaxis and were admitted to ICUs. The purpose of this observational study was to describe the epidemiology and management of these patients. METHODS: This was a multicentre retrospective study carried out in 23 French ICUs between 2012 and 2017. All patients who suffered anaphylaxis and were transferred to an ICU were included. Data were collected using an electronic database after approval by an ethics committee...
December 2020: British Journal of Anaesthesia
#37
REVIEW
Shilpadevi S Patil, Lu Sun, Charles J Fox, Kathryn E Anthony, Fallon A Anzalone, Paul M Fisher, Brook Girma, Genkai J Huang, Emily L Barsley, Elyse M Cornett, Richard D Urman, Alan D Kaye
Life-threatening hypersensitivity reactions are more likely to occur in patients with a history of allergy, atopy, or asthma. Hence, in a patient who presented with a history of multiple drug allergies (MDA), an allergological assessment should be performed prior to surgical procedure. Drug allergies, being one of the causes of catastrophic events occurring in the perioperative period, are of major concern to anesthesiologists. Neuromuscular blocking agents are regularly used during anesthesia and are one of the most common causes of perioperative anaphylaxis...
June 2020: Best Practice & Research. Clinical Anaesthesiology
#38
JOURNAL ARTICLE
Ismael Carrillo-Martin, Marco Caminati, Luciana K Tanno, Alexei Gonzalez-Estrada
PURPOSE OF REVIEW: Epinephrine is the only life-saving treatment of anaphylaxis. Prescription and administration rates of self-injectable epinephrine are generally low. It is unclear whether this is because of availability, low prescription rates, fear of using epinephrine, or a combination of these issues. RECENT FINDINGS: This review focuses on what self-injectable epinephrine devices (SIED), such as auto-injectors and prefilled syringes, are preferred by patients and healthcare professionals (HCP)...
October 2020: Current Opinion in Allergy and Clinical Immunology
#39
REVIEW
Jay Adam Lieberman, Julie Wang
PURPOSE OF REVIEW: Epinephrine is the agreed-upon first line treatment for anaphylaxis, yet it continues to be underused by patients/caregivers and providers alike. RECENT FINDINGS: There are unfortunately limited data on how epinephrine can best be utilized in anaphylaxis, which hinders how best to inform patients and providers. Studies reporting underuse suggest various barriers and themes on why this may happen. SUMMARY: Continued education of patients, caregivers, and providers is needed; however, is not likely to be enough to close the gap...
October 2020: Current Opinion in Allergy and Clinical Immunology
#40
JOURNAL ARTICLE
D A Tonetti, S M Desai, A Morrison, B A Gross, T G Jovin, B T Jankowitz, A P Jadhav
BACKGROUND AND PURPOSE: Management of contrast media allergies may lead to treatment delays in patients with acute ischemic stroke undergoing endovascular therapy. The optimal premedication strategy remains unclear. The aim of this report was to analyze our experience with emergent administration of premedication regimens before endovascular therapy. MATERIALS AND METHODS: We retrospectively reviewed prospective data for all patients undergoing endovascular therapy from 2012 to 2019 at an academic comprehensive stroke center...
September 2020: AJNR. American Journal of Neuroradiology
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
