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Pain

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13 papers 0 to 25 followers
By Michael Wansbrough Emergency Physician, Transport Physician and Director of the U of T CCFP(EM) Simulation Program based in Toronto
https://www.readbyqxmd.com/read/26418341/simvastatin-and-vitamin-d-for-migraine-prevention-a-randomized-controlled-trial
#1
RANDOMIZED CONTROLLED TRIAL
Catherine Buettner, Rony-Reuven Nir, Suzanne M Bertisch, Carolyn Bernstein, Aaron Schain, Murray A Mittleman, Rami Burstein
OBJECTIVE: The aim of this work was to assess efficacy and tolerability of simvastatin plus vitamin D for migraine prevention in adults with episodic migraine. METHODS: We performed a randomized, double-blind, placebo-controlled trial with a 12-week baseline period and 24-week intervention period in 57 adults with episodic migraine. Participants were randomly assigned to simvastatin 20 mg tablets twice-daily plus vitamin D3 1,000 international units capsules twice-daily or matching placebo tablets and capsules...
December 2015: Annals of Neurology
https://www.readbyqxmd.com/read/27038972/new-chronic-pain-treatments-in-the-outpatient-setting-review-article
#2
REVIEW
R Grandhe, D Souzdalnitski, K Gritsenko
Chronic pain is an issue encountered by many health care providers in their routine clinical practice. In addition to generalized patient suffering, this condition has significant clinical, psychological, and socioeconomic impact due to its widespread occurrence. The landscape of chronic pain management has been changing rapidly with an array of treatment innovations, better understanding of established therapies, and care coordination across specialties. In this article, we have reviewed emerging new modalities as well as transformation of established therapies by interventional, pharmacologic, rehabilitative, psychological, complimentary, and interdisciplinary approaches...
May 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27891062/results-from-10-years-of-a-cbt-pain-self-management-outpatient-program-for-complex-chronic-conditions
#3
Kathryn A Boschen, Edward Robinson, Kent A Campbell, Sarah Muir, Elvina Oey, Kristen Janes, Samantha R Fashler, Joel Katz
Background. Traditional unimodal interventions may be insufficient for treating complex pain, as they do not address cognitive and behavioural contributors to pain. Cognitive Behavioural Therapy (CBT) and physical exercise (PE) are empirically supported treatments that can reduce pain and improve quality of life. Objectives. To examine the outcomes of a pain self-management outpatient program based on CBT and PE at a rehabilitation hospital in Toronto, Ontario. Methods. The pain management group (PMG) consisted of 20 sessions over 10 weeks...
2016: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/27672692/do-autologous-blood-and-prp-injections-effectively-treat-tennis-elbow
#4
Luke Widstrom, Andrew Slattengren
Both approaches reduce pain, but the improvement with platelet-rich plasma (PRP) is not clinically meaningful. Autologous blood injections (ABIs) are more effective than corticosteroid injections for reducing pain and disability in patients with tennis elbow in both the short and long term.
September 2016: Journal of Family Practice
https://www.readbyqxmd.com/read/23710678/the-capsaicin-8-patch-for-neuropathic-pain-in-clinical-practice-a-retrospective-analysis
#5
Till Wagner, Chris Poole, Andrea Roth-Daniek
OBJECTIVE: To investigate the response of patients with peripheral neuropathic pain (PNP) to capsaicin 8% patch treatment in a clinical setting. DESIGN: Retrospective analysis. SETTING: The Clinic for Pain Therapy and Palliative Medicine at the Medical Centre for the region of Aachen, Germany. SUBJECTS: Patients diagnosed with PNP who attended the clinic for capsaicin 8% patch treatment between January 13, 2010 and February 7, 2011...
August 2013: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27408698/mechanisms-of-low-back-pain-a-guide-for-diagnosis-and-therapy
#6
REVIEW
Massimo Allegri, Silvana Montella, Fabiana Salici, Adriana Valente, Maurizio Marchesini, Christian Compagnone, Marco Baciarello, Maria Elena Manferdini, Guido Fanelli
Chronic low back pain (CLBP) is a chronic pain syndrome in the lower back region, lasting for at least 3 months. CLBP represents the second leading cause of disability worldwide being a major welfare and economic problem. The prevalence of CLBP in adults has increased more than 100% in the last decade and continues to increase dramatically in the aging population, affecting both men and women in all ethnic groups, with a significant impact on functional capacity and occupational activities. It can also be influenced by psychological factors, such as stress, depression and/or anxiety...
2016: F1000Research
https://www.readbyqxmd.com/read/26332001/opioid-receptors
#7
REVIEW
Christoph Stein
Opioids are the oldest and most potent drugs for the treatment of severe pain. Their clinical application is undisputed in acute (e.g., postoperative) and cancer pain, but their long-term use in chronic pain has met increasing scrutiny. This article reviews mechanisms underlying opioid analgesia and other opioid actions. It discusses the structure, function, and plasticity of opioid receptors; the central and peripheral sites of analgesic actions and side effects; endogenous and exogenous opioid receptor ligands; and conventional and novel opioid compounds...
2016: Annual Review of Medicine
https://www.readbyqxmd.com/read/26944242/central-neuropathic-pain-syndromes
#8
REVIEW
James C Watson, Paola Sandroni
Chronic pain is common in patients with neurologic complications of a central nervous system insult such as stroke. The pain is most commonly musculoskeletal or related to obligatory overuse of neurologically unaffected limbs. However, neuropathic pain can result directly from the central nervous system injury. Impaired sensory discrimination can make it challenging to differentiate central neuropathic pain from other pain types or spasticity. Central neuropathic pain may also begin months to years after the injury, further obscuring recognition of its association with a past neurologic injury...
March 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/26945235/relieving-patients-pain-with-expectation-interventions-a-meta-analysis
#9
Kaya J Peerdeman, Antoinette I M van Laarhoven, Sascha M Keij, Lene Vase, Maroeska M Rovers, Madelon L Peters, Andrea W M Evers
Patients' expectations are important predictors of the outcome of analgesic treatments, as demonstrated predominantly in research on placebo effects. Three commonly investigated interventions that have been found to induce expectations (verbal suggestion, conditioning, and mental imagery) entail promising, brief, and easy-to-implement adjunctive procedures for optimizing the effectiveness of analgesic treatments. However, evidence for their efficacy stems mostly from research on experimentally evoked pain in healthy samples, and these findings might not be directly transferable to clinical populations...
June 2016: Pain
https://www.readbyqxmd.com/read/24264721/myofascial-trigger-points-peripheral-or-central-phenomenon
#10
REVIEW
César Fernández-de-las-Peñas, Jan Dommerholt
Trigger points (TrP) are hyperirritable spots in a taut band of a skeletal muscle, which usually have referred pain. There is controversy over whether TrP are a peripheral or central nervous system phenomenon. Referred pain, the most characteristic sign of TrP, is a central phenomenon initiated and activated by peripheral sensitization, whereby the peripheral nociceptive input from the muscle can sensitize dorsal horn neurons that were previously silent. TrP are a peripheral source of nociception, and act as ongoing nociceptive stimuli contributing to pain propagation and widespread pain...
January 2014: Current Rheumatology Reports
https://www.readbyqxmd.com/read/24645933/treatment-of-myofascial-pain
#11
Mehul J Desai, Matthew C Bean, Thomas W Heckman, Dhinu Jayaseelan, Nick Moats, Andrew Nava
SUMMARY The objective of this article was to perform a narrative review regarding the treatment of myofascial pain syndrome and to provide clinicians with treatment recommendations. This paper reviews the efficacy of various myofascial pain syndrome treatment modalities, including pharmacological therapy, injection-based therapies and physical therapy interventions. Outcomes evaluated included pain (visual analog scale), pain pressure threshold and range of motion. The evidence found significant benefit with multiple treatments, including diclofenac patch, thiocolchicoside and lidocaine patches...
January 2013: Pain Management
https://www.readbyqxmd.com/read/24407900/the-substantial-impact-of-ultrasound-guided-regional-anaesthesia-on-the-clinical-practice-of-peripheral-nerve-blocks
#12
Piotr Nowakowski, Andrzej Bieryło, Larysa Duniec, Dariusz Kosson, Tomasz Łazowski
BACKGROUND: Ultrasound-guided (US-guided) regional anaesthesia has gained worldwide popularity in recent years owing to the benefits the method offers to patients. The 1st Department of Anaesthesiology and Intensive Care of Warsaw Medical University was one of the first centres in Poland to employ US-guided peripheral nerve blocks (PNB) on a routine basis. The technique was incorporated into the institution's clinical practice from 2007. The purpose of this study was to retrospectively assess changes in the clinical practice of US-guided versus non US-guided PNBs over six years of experience with the technique...
October 2013: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/21138388/a-randomized-controlled-trial-of-intra-articular-prolotherapy-versus-steroid-injection-for-sacroiliac-joint-pain
#13
RANDOMIZED CONTROLLED TRIAL
Woong Mo Kim, Hyung Gon Lee, Cheol Won Jeong, Chang Mo Kim, Myung Ha Yoon
OBJECTIVES: Controversy exists regarding the efficacy of ligament prolotherapy in alleviating sacroiliac joint pain. The inconsistent success rates reported in previous studies may be attributed to variability in patient selection and techniques between studies. It was hypothesized that intra-articular prolotherapy for patients with a positive response to diagnostic block may mitigate the drawbacks of ligament prolotherapy. The purpose of this study was to evaluate the efficacy and long-term effectiveness of intra-articular prolotherapy in relieving sacroiliac joint pain, compared with intra-articular steroid injection...
December 2010: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
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