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https://www.readbyqxmd.com/read/27075872/after-topcat-what-to-do-now-in-heart-failure-with-preserved-ejection-fraction
#1
REVIEW
Akshay S Desai, Pardeep S Jhund
Although patients with heart failure and preserved ejection fraction (HF-PEF) represent nearly half of the population with chronic heart failure, few evidence-based medical therapies are available. The neutral overall results of the TOPCAT trial of spironolactone in HF-PEF leave clinicians who treat heart failure with an ongoing clinical dilemma. In this review, we outline an approach to the clinical management of the patient with HF-PEF synthesizing data from available clinical trials and expert consensus.
November 1, 2016: European Heart Journal
https://www.readbyqxmd.com/read/18158481/acute-decompensated-heart-failure-and-the-cardiorenal-syndrome
#2
REVIEW
Kelly V Liang, Amy W Williams, Eddie L Greene, Margaret M Redfield
Heart failure is one of the leading causes of hospitalizations in the United States. Concomitant and significant renal dysfunction is common in patients with heart failure. Increasingly, the syndrome of heart failure is one of cardiorenal failure, in which concomitant cardiac and renal dysfunctions exist, with each accelerating the progression of the other. One fourth of patients hospitalized for the treatment of acute decompensated heart failure will experience significant worsening of renal function, which is associated with worse outcomes...
January 2008: Critical Care Medicine
https://www.readbyqxmd.com/read/25552544/can-vbg-analysis-replace-abg-analysis-in-emergency-care
#3
REVIEW
Anne-Maree Kelly
Blood gas analysis is an integral part of the assessment of emergency department (ED) patients with acute respiratory or metabolic disease. Traditionally ABG analyses have been used, but increasingly, emergency clinicians are using venous blood gas (VBG) analyses. This has been challenged, especially by respiratory physicians, as being too inaccurate. This clinical review, using case examples, summarises the evidence supporting use of VBG to guide management decisions. Arteriovenous agreement for pH is such that values are clinically interchangeable and agreement for bicarbonate is also close...
February 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/26822746/mri-criteria-for-the-diagnosis-of-multiple-sclerosis-magnims-consensus-guidelines
#4
REVIEW
Massimo Filippi, Maria A Rocca, Olga Ciccarelli, Nicola De Stefano, Nikos Evangelou, Ludwig Kappos, Alex Rovira, Jaume Sastre-Garriga, Mar Tintorè, Jette L Frederiksen, Claudio Gasperini, Jacqueline Palace, Daniel S Reich, Brenda Banwell, Xavier Montalban, Frederik Barkhof
In patients presenting with a clinically isolated syndrome, MRI can support and substitute clinical information in the diagnosis of multiple sclerosis by showing disease dissemination in space and time and by helping to exclude disorders that can mimic multiple sclerosis. MRI criteria were first included in the diagnostic work-up for multiple sclerosis in 2001, and since then several modifications to the criteria have been proposed in an attempt to simplify lesion-count models for showing disease dissemination in space, change the timing of MRI scanning to show dissemination in time, and increase the value of spinal cord imaging...
March 2016: Lancet Neurology
https://www.readbyqxmd.com/read/25698681/do-not-drown-the-patient-appropriate-fluid-management-in-critical-illness
#5
Kees H Polderman, Joseph Varon
Administering intravenous fluids to support the circulation in critically ill patients has been a mainstay of emergency medicine and critical care for decades, especially (but not exclusively) in patients with distributive or hypovolemic shock. However, in recent years, this automatic use of large fluid volumes is beginning to be questioned. Analysis from several large trials in severe sepsis and/or acute respiratory distress syndrome have shown independent links between volumes of fluid administered and outcome; conservative fluid strategies have also been associated with lower mortality in trauma patients...
March 2015: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/26108552/the-great-fluid-debate-saline-or-so-called-balanced-salt-solutions
#6
REVIEW
Maristella Santi, Sebastiano A G Lava, Pietro Camozzi, Olivier Giannini, Gregorio P Milani, Giacomo D Simonetti, Emilio F Fossali, Mario G Bianchetti, Pietro B Faré
BACKGROUND: Intravenous fluids are commonly prescribed in childhood. 0.9 % saline is the most-used fluid in pediatrics as resuscitation or maintenance solution. Experimental studies and observations in adults suggest that 0.9 % saline is a poor candidate for fluid resuscitation. Although anesthesiologists, intensive care specialists, perioperative physicians and nephrologists have been the most active in this debate, this issue deserves some physiopathological considerations also among pediatricians...
June 25, 2015: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/26545940/2015-american-college-of-rheumatology-guideline-for-the-treatment-of-rheumatoid-arthritis
#7
REVIEW
Jasvinder A Singh, Kenneth G Saag, S Louis Bridges, Elie A Akl, Raveendhara R Bannuru, Matthew C Sullivan, Elizaveta Vaysbrot, Christine McNaughton, Mikala Osani, Robert H Shmerling, Jeffrey R Curtis, Daniel E Furst, Deborah Parks, Arthur Kavanaugh, James O'Dell, Charles King, Amye Leong, Eric L Matteson, John T Schousboe, Barbara Drevlow, Seth Ginsberg, James Grober, E William St Clair, Elizabeth Tindall, Amy S Miller, Timothy McAlindon
OBJECTIVE: To develop a new evidence-based, pharmacologic treatment guideline for rheumatoid arthritis (RA). METHODS: We conducted systematic reviews to synthesize the evidence for the benefits and harms of various treatment options. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology to rate the quality of evidence. We employed a group consensus process to grade the strength of recommendations (either strong or conditional)...
January 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/26559575/case-records-of-the-massachusetts-general-hospital-case-35-2015-a-72-year-old-woman-with-proteinuria-and-a-kidney-mass
#8
D Bora Hazar, Nwamaka D Eneanya, Aoife Kilcoyne, Ivy A Rosales
A 72-year-old woman presented with flank pain, proteinuria, and a new kidney mass. Magnetic resonance imaging of the kidney revealed a complex, solid mass (3 cm x 2.9 cm x 2.9 cm) in the lower pole of the right kidney. Diagnostic tests were performed.
November 12, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/26068897/fluid-therapy-in-2015-and-beyond-the-mini-fluid-challenge-and-mini-fluid-bolus-approach
#9
EDITORIAL
P E Marik
No abstract text is available yet for this article.
September 2015: British Journal of Anaesthesia
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