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Diffusion

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2 papers 0 to 25 followers
By BRUNO TRIAIRE CMO at OLEA MEDICAL
https://www.readbyqxmd.com/read/28856177/intravoxel-incoherent-motion-ivim-histogram-biomarkers-for-prediction-of-neoadjuvant-treatment-response-in-breast-cancer-patients
#1
Gene Y Cho, Lucas Gennaro, Elizabeth J Sutton, Emily C Zabor, Zhigang Zhang, Dilip Giri, Linda Moy, Daniel K Sodickson, Elizabeth A Morris, Eric E Sigmund, Sunitha B Thakur
OBJECTIVE: To examine the prognostic capabilities of intravoxel incoherent motion (IVIM) metrics and their ability to predict response to neoadjuvant treatment (NAT). Additionally, to observe changes in IVIM metrics between pre- and post-treatment MRI. METHODS: This IRB-approved, HIPAA-compliant retrospective study observed 31 breast cancer patients (32 lesions). Patients underwent standard bilateral breast MRI along with diffusion-weighted imaging before and after NAT...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/25260092/quantitative-non-gaussian-diffusion-and-intravoxel-incoherent-motion-magnetic-resonance-imaging-differentiation-of-malignant-and-benign-breast-lesions
#2
Mami Iima, Kojiro Yano, Masako Kataoka, Masaki Umehana, Katsutoshi Murata, Shotaro Kanao, Kaori Togashi, Denis Le Bihan
OBJECTIVES: The purpose of this study was to explore the potential of non-Gaussian diffusion and perfusion magnetic resonance imaging (MRI) using intravoxel incoherent motion (IVIM) MRI for the diagnosis of breast lesions. MATERIALS AND METHODS: This study included 26 women with breast lesions. Diffusion-weighted images were acquired using 16 b values up to 2500 s/mm and analyzed using a kurtosis diffusion model (apparent diffusion coefficient [ADC0] and kurtosis [K]) for the diffusion component and IVIM model (perfusion fraction [fIVIM] and pseudodiffusion coefficient [D*]) for the perfusion component...
April 2015: Investigative Radiology
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