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Sunitinib Ca Prostata

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J L Lee, M K Kim, I Park, J-H Ahn, D H Lee, H M Ryoo, C Song, B Hong, J H Hong, H Ahn
BACKGROUND: The standard sunitinib schedule, 4 weeks on, followed by 2 weeks off (4/2 schedule), is associated with troublesome toxicities, and maintenance of adequate sunitinib dosing and drug levels, which are essential for achieving an optimal treatment outcome, is challenging. The objective of this study was to investigate the efficacy and safety of an alternative sunitinib dosing schedule of 2 weeks on and 1 week off (2/1 schedule) compared with the standard sunitinib schedule of 4 weeks on and 2 weeks off (4/2 schedule)...
November 2015: Annals of Oncology: Official Journal of the European Society for Medical Oncology
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