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38 papers 0 to 25 followers
By Andreas Tarnaris Consultant Neurosurgeon
https://www.readbyqxmd.com/read/28269098/fall-detection-algorithms-for-real-world-falls-harvested-from-lumbar-sensors-in-the-elderly-population-a-machine-learning-approach
#1
Alan K Bourke, Jochen Klenk, Lars Schwickert, Kamiar Aminian, Espen A F Ihlen, Sabato Mellone, Jorunn L Helbostad, Lorenzo Chiari, Clemens Becker
Automatic fall detection will promote independent living and reduce the consequences of falls in the elderly by ensuring people can confidently live safely at home for linger. In laboratory studies inertial sensor technology has been shown capable of distinguishing falls from normal activities. However less than 7% of fall-detection algorithm studies have used fall data recorded from elderly people in real life. The FARSEEING project has compiled a database of real life falls from elderly people, to gain new knowledge about fall events and to develop fall detection algorithms to combat the problems associated with falls...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28193454/new-developments-in-brain-research-of-internet-and-gaming-disorder
#2
REVIEW
Aviv Weinstein, Abigail Livny, Abraham Weizman
There is evidence that the neural mechanisms underlying Internet Gaming Disorder (IGD) resemble those of drug addiction. Functional Magnetic Resonance Imaging (fMRI) studies of the resting state and measures of gray matter volume have shown that Internet game playing was associated with changes to brain regions responsible for attention and control, impulse control, motor function, emotional regulation, sensory-motor coordination. Furthermore, Internet game playing was associated with lower white matter density in brain regions that are involved in decision-making, behavioral inhibition and emotional regulation...
April 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28034986/influence-of-sexual-hormones-on-neural-orofacial-perception
#3
Bruna Alves, Flavia Ibuki, Alyne Simões Gonçalves, Manoel Jacobsen Teixeira, Silvia Regina Dowgan Tesseroli De Siqueira
Objective: To investigate the trigeminal somatosensory (thermal, pain, tactile, vibratory, and electric), gustative (salty, bitter, sweet, sour), and olfactory thresholds in healthy women during the menstrual cycle and investigate any association with estradiol and progesterone levels in saliva. Methods: We examined/tested 39 women between age 19 and 47 years and with regular menstrual cycles and no comorbidities. All women were informed about the purposes of the study, and only those who signed the informed consent were included...
August 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27973434/performance-evaluation-of-state-of-the-art-systems-for-physical-activity-classification-of-older-subjects-using-inertial-sensors-in-a-real-life-scenario-a-benchmark-study
#4
Muhammad Awais, Luca Palmerini, Alan K Bourke, Espen A F Ihlen, Jorunn L Helbostad, Lorenzo Chiari
The popularity of using wearable inertial sensors for physical activity classification has dramatically increased in the last decade due to their versatility, low form factor, and low power requirements. Consequently, various systems have been developed to automatically classify daily life activities. However, the scope and implementation of such systems is limited to laboratory-based investigations. Furthermore, these systems are not directly comparable, due to the large diversity in their design (e.g., number of sensors, placement of sensors, data collection environments, data processing techniques, features set, classifiers, cross-validation methods)...
December 11, 2016: Sensors
https://www.readbyqxmd.com/read/27440524/radiation-protection-for-the-fluoroscopy-operator-and-staff
#5
Quinn C Meisinger, Cosette M Stahl, Michael P Andre, Thomas B Kinney, Isabel G Newton
OBJECTIVE: The purposes of this article are to review available data regarding the range of protection devices and garments with a focus on eye protection and to summarize techniques for reducing scatter radiation exposure. CONCLUSION: Fluoroscopy operators and staff can greatly reduce their radiation exposure by wearing properly fitted protective garments, positioning protective devices to block scatter radiation, and adhering to good radiation practices. By understanding the essentials of radiation physics, protective equipment, and the features of each imaging system, operators and staff can capitalize on opportunities for radiation protection while minimizing ergonomic strain...
October 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27706136/evidence-for-a-limit-to-human-lifespan
#6
Xiao Dong, Brandon Milholland, Jan Vijg
Driven by technological progress, human life expectancy has increased greatly since the nineteenth century. Demographic evidence has revealed an ongoing reduction in old-age mortality and a rise of the maximum age at death, which may gradually extend human longevity. Together with observations that lifespan in various animal species is flexible and can be increased by genetic or pharmaceutical intervention, these results have led to suggestions that longevity may not be subject to strict, species-specific genetic constraints...
October 13, 2016: Nature
https://www.readbyqxmd.com/read/27830790/a-brain-spine-interface-alleviating-gait-deficits-after-spinal-cord-injury-in-primates
#7
Marco Capogrosso, Tomislav Milekovic, David Borton, Fabien Wagner, Eduardo Martin Moraud, Jean-Baptiste Mignardot, Nicolas Buse, Jerome Gandar, Quentin Barraud, David Xing, Elodie Rey, Simone Duis, Yang Jianzhong, Wai Kin D Ko, Qin Li, Peter Detemple, Tim Denison, Silvestro Micera, Erwan Bezard, Jocelyne Bloch, Grégoire Courtine
Spinal cord injury disrupts the communication between the brain and the spinal circuits that orchestrate movement. To bypass the lesion, brain-computer interfaces have directly linked cortical activity to electrical stimulation of muscles, and have thus restored grasping abilities after hand paralysis. Theoretically, this strategy could also restore control over leg muscle activity for walking. However, replicating the complex sequence of individual muscle activation patterns underlying natural and adaptive locomotor movements poses formidable conceptual and technological challenges...
November 10, 2016: Nature
https://www.readbyqxmd.com/read/27804259/neuromodulation-by-cerebrovasculature-bdnf-is-it-much-greater-than-we-think
#8
EDITORIAL
C J Ek
No abstract text is available yet for this article.
November 2, 2016: Acta Physiologica
https://www.readbyqxmd.com/read/27803649/two-photon-holographic-stimulation-of-reachr
#9
Emmanuelle Chaigneau, Emiliano Ronzitti, Marta A Gajowa, Gilberto J Soler-Llavina, Dimitrii Tanese, Anthony Y B Brureau, Eirini Papagiakoumou, Hongkui Zeng, Valentina Emiliani
Optogenetics provides a unique approach to remotely manipulate brain activity with light. Reaching the degree of spatiotemporal control necessary to dissect the role of individual cells in neuronal networks, some of which reside deep in the brain, requires joint progress in opsin engineering and light sculpting methods. Here we investigate for the first time two-photon stimulation of the red-shifted opsin ReaChR. We use two-photon (2P) holographic illumination to control the activation of individually chosen neurons expressing ReaChR in acute brain slices...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27504261/disrupted-functional-connectivity-in-adolescent-obesity
#10
Laura Moreno-Lopez, Oren Contreras-Rodriguez, Carles Soriano-Mas, Emmanuel A Stamatakis, Antonio Verdejo-Garcia
BACKGROUND/OBJECTIVE: Obesity has been associated with brain alterations characterised by poorer interaction between a hypersensitive reward system and a comparatively weaker prefrontal-cognitive control system. These alterations may occur as early as in adolescence, but this notion remains unclear, as no studies so far have examined global functional connectivity in adolescents with excess weight. SUBJECTS/METHODS: We investigated functional connectivity in a sample of 60 adolescents with excess weight and 55 normal weight controls...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27165936/normal-pressure-hydrocephalus-case-report-self-documented-over-8-years-with-the-author-s-observations
#11
Omer Elsabbagh
Normal-pressure hydrocephalus is an almost curable disease, but the results of management are still not encouraging owing to the deceptive nature of the disease and its sensitivity to treatment. This has made the management of the disease controversial. The following self-documented report clarifies this. I have reported my experience in a scientific manner so that my colleagues can understand thoroughly certain facts related to intracranial hypertension. Achieving the optimal adjustment of the valve is a real challenge...
2016: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/27302679/intraspinal-transplantation-of-subventricular-zone-derived-neural-progenitor-cells-improves-phrenic-motor-output-after-high-cervical-spinal-cord-injury
#12
M S Sandhu, H H Ross, K Z Lee, B K Ormerod, P J Reier, D D Fuller
Following spinal cord injury (SCI), intraspinal transplantation of neural progenitor cells (NPCs) harvested from the forebrain sub-ventricular zone (SVZ) can improve locomotor outcomes. Cervical SCI often results in respiratory-related impairments, and here we used an established model cervical SCI (C2 hemisection, C2Hx) to confirm the feasibility of mid-cervical transplantation of SVZ-derived NPCs and the hypothesis that that this procedure would improve spontaneous respiratory motor recovery. NPCs were isolated from the SVZ of enhanced green fluorescent protein (GFP) expressing neonatal rats, and then intraspinally delivered immediately caudal to an acute C2Hx lesion in adult non-GFP rats...
January 2017: Experimental Neurology
https://www.readbyqxmd.com/read/27333899/the-major-influence-of-the-atmosphere-on-intracranial-pressure-an-observational-study
#13
Leszek Herbowski
The impact of the atmosphere on human physiology has been studied widely within the last years. In practice, intracranial pressure is a pressure difference between intracranial compartments and the surrounding atmosphere. This means that gauge intracranial pressure uses atmospheric pressure as its zero point, and therefore, this method of pressure measurement excludes the effects of barometric pressure's fluctuation. The comparison of these two physical quantities can only take place through their absolute value relationship...
January 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/27285540/is-life-worth-living-decompressive-craniectomy-and-the-disability-paradox
#14
Stephen Honeybul, Grant R Gillett, Kwok M Ho, Courtney Janzen, Kate Kruger
No abstract text is available yet for this article.
September 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27083532/google-trends-new-evidence-for-seasonality-of-multiple-sclerosis
#15
LETTER
Marcello Moccia, Raffaele Palladino, Andrea Falco, Francesco Saccà, Roberta Lanzillo, Vincenzo Brescia Morra
No abstract text is available yet for this article.
September 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27118036/-journal-bias-in-peer-reviewed-literature-an-analysis-of-the-surgical-high-grade-glioma-literature
#16
Brian R Hirshman, Laurie A Jones, Jessica A Tang, James A Proudfoot, Kathleen M Carley, Bob S Carter, Clark C Chen
The core premise of evidence-based medicine is that clinical decisions are informed by the peer-reviewed literature. To extract meaningful conclusions from this literature, one must first understand the various forms of biases inherent within the process of peer review. We performed an exhaustive search that identified articles exploring the question of whether survival benefit was associated with maximal high-grade glioma (HGG) resection and analysed this literature for patterns of publication. We found that the distribution of these 108 articles among the 26 journals to be non-random (p<0...
November 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27172939/neuronal-network-disintegration-common-pathways-linking-neurodegenerative-diseases
#17
REVIEW
Rebekah M Ahmed, Emma M Devenney, Muireann Irish, Arne Ittner, Sharon Naismith, Lars M Ittner, Jonathan D Rohrer, Glenda M Halliday, Andrew Eisen, John R Hodges, Matthew C Kiernan
Neurodegeneration refers to a heterogeneous group of brain disorders that progressively evolve. It has been increasingly appreciated that many neurodegenerative conditions overlap at multiple levels and therefore traditional clinicopathological correlation approaches to better classify a disease have met with limited success. Neuronal network disintegration is fundamental to neurodegeneration, and concepts based around such a concept may better explain the overlap between their clinical and pathological phenotypes...
November 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27178897/early-blood-pressure-lowering-in-patients-with-intracerebral-haemorrhage-and-prior-use-of-antithrombotic-agents-pooled-analysis-of-the-interact-studies
#18
RANDOMIZED CONTROLLED TRIAL
Lili Song, Else Charlotte Sandset, Hisatomi Arima, Emma Heeley, Candice Delcourt, Guofeng Chen, Jie Yang, Guojun Wu, Xia Wang, Pablo M Lavados, Yining Huang, Christian Stapf, Jiguang Wang, Thompson G Robinson, John Chalmers, Richard I Lindley, Craig S Anderson
OBJECTIVE: Antithrombotic agents increase risks of intracerebral haemorrhage (ICH) and associated adverse outcomes. We determined differential effects of early blood pressure (BP) lowering in patients with/without antithrombotic-associated ICH in the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trials (INTERACT1 and 2). DESIGN: Post hoc pooled analyses of the INTERACT studies-international, multicentre, prospective, open, blinded end point trials of patients with ICH (<6 h) and elevated systolic BP (SBP 150-180 mm Hg) randomly assigned to intensive (target SBP <140 mm Hg) or guideline-based (SBP <180 mm Hg) BP management...
December 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/26956423/a-subcutaneous-cellular-implant-for-passive-immunization-against-amyloid-%C3%AE-reduces-brain-amyloid-and-tau-pathologies
#19
Aurélien Lathuilière, Vanessa Laversenne, Alberto Astolfo, Erhard Kopetzki, Helmut Jacobsen, Marco Stampanoni, Bernd Bohrmann, Bernard L Schneider, Patrick Aebischer
Passive immunization against misfolded toxic proteins is a promising approach to treat neurodegenerative disorders. For effective immunotherapy against Alzheimer's disease, recent clinical data indicate that monoclonal antibodies directed against the amyloid-β peptide should be administered before the onset of symptoms associated with irreversible brain damage. It is therefore critical to develop technologies for continuous antibody delivery applicable to disease prevention. Here, we addressed this question using a bioactive cellular implant to deliver recombinant anti-amyloid-β antibodies in the subcutaneous tissue...
May 2016: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/27105800/periorbital-rejuvenation-overview-of-nonsurgical-treatment-options
#20
REVIEW
Dee Anna Glaser, Anastasia Kurta
Numerous nonsurgical options for periorbital rejuvenation are available and can be used alone or as adjuncts to other nonsurgical and surgical options. Topicals, chemical peels, laser resurfacing, and dermabrasion therapy, along with neuromodulators and fillers, can be used to enhance the appearance of the periorbital region.
May 2016: Facial Plastic Surgery Clinics of North America
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