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SPRINT

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38 papers 25 to 100 followers Papers related to the trial "Randomized Trial of Intensive versus Standard Blood-Pressure Control"
By Daniel Schwartz Passionate about knowledge translation http://qxmd.com/read
https://www.readbyqxmd.com/read/27551025/automated-office-blood-pressure-incorporating-sprint-into-clinical-practice
#1
Martin G Myers
No abstract text is available yet for this article.
August 22, 2016: American Journal of Hypertension
https://www.readbyqxmd.com/read/27566331/bp-targets-in-hypertension-what-should-we-do-now-that-sprint-is-out
#2
REVIEW
Hemal Bhatt, Lama Ghazi, David Calhoun, Suzanne Oparil
Systolic blood pressure (SBP) is an important predictor of cardiovascular disease (CVD) outcomes. Lowering SBP has been shown to reduce CVD morbidity and mortality, but the optimal SBP target continues to be a topic of intense debate. The Systolic Blood Pressure Intervention Trial (SPRINT) reported a significantly lower risk for CVD outcomes and all-cause mortality by targeting SBP <120 mmHg compared with <140 mmHg in a population of hypertensive persons at high CV risk. In this review, we discuss the strengths, limitations, and generalizability of SPRINT findings to other hypertensive populations that were excluded from the trial, including those with diabetes or prior stroke, <50 years old, and at lower CVD risk...
October 2016: Current Cardiology Reports
https://www.readbyqxmd.com/read/27619922/should-patients-with-cardiovascular-risk-factors-receive-intensive-treatment-of-hypertension-to-120-80-mm%C3%A2-hg-target-a-protagonist-view-from-the-sprint-trial-systolic-blood-pressure-intervention-trial
#3
https://www.readbyqxmd.com/read/27627731/cost-effectiveness-of-intensive-blood-pressure-management
#4
Ilana B Richman, Michael Fairley, Mads Emil Jørgensen, Alejandro Schuler, Douglas K Owens, Jeremy D Goldhaber-Fiebert
Importance: Among high-risk patients with hypertension, targeting a systolic blood pressure of 120 mm Hg reduces cardiovascular morbidity and mortality compared with a higher target. However, intensive blood pressure management incurs additional costs from treatment and from adverse events. Objective: To evaluate the incremental cost-effectiveness of intensive blood pressure management compared with standard management. Design, Setting, and Participants: This cost-effectiveness analysis conducted from September 2015 to August 2016 used a Markov cohort model to estimate cost-effectiveness of intensive blood pressure management among 68-year-old high-risk adults with hypertension but not diabetes...
November 1, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27633256/more-versus-less-blood-pressure-lowering-an-update
#5
Emily R Atkins, Anthony Rodgers
PURPOSE: This article summarizes the results of a recent systematic review and meta-analysis of the safety and efficacy of intensive blood pressure (BP) lowering, including an update with the SPRINT (Systolic Blood Pressure Intervention Trial) results. We discuss the consistency of results within this set of trials (eg, ACCORD [Action to Control Cardiovascular Risk in Diabetes] and SPRINT) and the results in the context of other BP-lowering trials, including the recently published HOPE3 (Heart Outcomes Prevention Evaluation-3) study...
September 12, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27639873/isolated-systolic-hypertension-an-update-after-sprint
#6
REVIEW
Chirag Bavishi, Sangita Goel, Franz H Messerli
Isolated systolic hypertension is the most common hemodynamic form of hypertension in the elderly. With a rapidly aging population, the prevalence of hypertension, particularly isolated systolic hypertension, is expected to increase substantially. This phenomenon of increasing systolic pressure in the elderly is believed to be secondary to pathophysiological changes of aging as well as modifiable risk factors. Isolated systolic hypertension is associated with substantial mortality and morbidity, particularly of cerebrovascular disease...
December 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27427441/worsening-renal-function-and-outcome-in-heart-failure-patients-with-reduced-and-preserved-ejection-fraction-and-the-impact-of-angiotensin-receptor-blocker-treatment-data-from-the-charm-study-programme
#7
Kevin Damman, Scott D Solomon, Marc A Pfeffer, Karl Swedberg, Salim Yusuf, James B Young, Jean L Rouleau, Christopher B Granger, John J V McMurray
AIMS: We investigated the association between worsening renal function (WRF) that occurs during renin-angiotensin-aldosterone system inhibition initation and outcome in heart failure (HF) patients with preserved ejection fraction (HFPEF) and compared this with HF patients with reduced ejection fraction (HFREF). METHODS AND RESULTS: We examined changes in estimated glomerular filtration rate (GFR) and the relationship between WRF (defined as ≥26.5 µmol/L and ≥25% increase in serum creatinine from baseline to 6 weeks) and outcome, according to randomized treatment, in patients with HFREF (EF <45%; n = 1569) and HFPEF (EF ≥45%; n = 836) in the CHARM programme...
December 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27038200/a-short-history-of-automated-office-blood-pressure-15-years-to-sprint
#8
Martin G Myers
No abstract text is available yet for this article.
August 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/27012910/how-does-sprint-systolic-blood-pressure-intervention-trial-direct-hypertension-treatment-targets-for-ckd
#9
EDITORIAL
Sandra J Taler
No abstract text is available yet for this article.
July 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27021011/is-the-sprint-blood-pressure-treatment-target-of-120-80-mm-hg-relevant-for-children
#10
REVIEW
Bonita Falkner, Samuel S Gidding
No abstract text is available yet for this article.
May 2016: Hypertension
https://www.readbyqxmd.com/read/26882581/how-low-can-you-go-what-can-we-take-from-the-sprint-trial
#11
REVIEW
William Hayes, James Clem
No abstract text is available yet for this article.
January 2016: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/26902415/let-s-not-sprint-to-judgment-about-new-blood-pressure-goals
#12
Eduardo Ortiz, Paul A James
No abstract text is available yet for this article.
May 17, 2016: Annals of Internal Medicine
https://www.readbyqxmd.com/read/26911833/recruitment-strategies-and-challenges-in-a-large-intervention-trial-systolic-blood-pressure-intervention-trial
#13
Thomas M Ramsey, Joni K Snyder, Laura C Lovato, Christianne L Roumie, Steven P Glasser, Nora M Cosgrove, Christine M Olney, Rocky H Tang, Karen C Johnson, Carolyn H Still, Lisa H Gren, Jeffery C Childs, Osa L Crago, John H Summerson, Sandy M Walsh, Letitia H Perdue, Denise M Bankowski, David C Goff
BACKGROUND: The Systolic Blood Pressure Intervention Trial is a multicenter, randomized clinical trial of 9361 participants with hypertension who are ≥50 years old. The trial is designed to evaluate the effect of intensive systolic blood pressure control (systolic blood pressure goal <120 mm Hg) compared to standard control (systolic blood pressure goal <140 mm Hg) on cardiovascular events using commonly prescribed antihypertensive medications and lifestyle modification...
June 2016: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/26846945/sprint-to-whom-do-the-results-apply
#14
EDITORIAL
Alan H Gradman
No abstract text is available yet for this article.
February 9, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/26732129/which-patients-does-the-sprint-study-not-apply-to-and-what-are-the-appropriate-blood-pressure-goals-in-these-populations
#15
Debbie L Cohen, Raymond R Townsend
No abstract text is available yet for this article.
May 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/26743157/the-sprint-study-outcome-may-be-driven-by-difference-in-diuretic-treatment-demasking-heart-failure-and-study-design-may-support-systolic-blood-pressure-target-below-140%C3%A2-mmhg-rather-than-below-120%C3%A2-mmhg
#16
EDITORIAL
Sverre E Kjeldsen, Krzysztof Narkiewicz, Thomas Hedner, Giuseppe Mancia
No abstract text is available yet for this article.
2016: Blood Pressure
https://www.readbyqxmd.com/read/26762523/sps3-evidence-supports-intensive-blood-pressure-control
#17
EDITORIAL
Suzanne Oparil
No abstract text is available yet for this article.
February 9, 2016: Circulation
https://www.readbyqxmd.com/read/26774234/are-we-endangering-hypertensive-patients-by-overzealous-treatment-that-induces-diastolic-hypotension-a-sprint-to-the-answer
#18
EDITORIAL
Ross D Feldman, Raj S Padwal
No abstract text is available yet for this article.
May 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/26804018/hypertension-rest-before-blood-pressure-measurement-a-lesson-from-sprint
#19
COMMENT
Rajiv Agarwal
No abstract text is available yet for this article.
March 2016: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/26806825/a-sprint-to-the-finish-or-just-the-beginning-implications-of-the-sprint-results-for-nephrologists
#20
Michael V Rocco, Alfred K Cheung
The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated a significant reduction in major cardiovascular events and all-cause mortality with intensive blood pressure control in older individuals at high cardiovascular risk, including patients with chronic kidney disease and mild proteinuria. Nephrologists should consider the SPRINT results when determining the optimal blood pressure target for patients with chronic kidney disease.
February 2016: Kidney International
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