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Bronquiolitis obliterante

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9 papers 0 to 25 followers
Xueyan Wang, Changshan Liu, Mengjuan Wang, Y I Zhang, Hewen Li, Geli Liu
The aim of the present study was to outline any predisposing factors and clinical and radiological features of post-infectious bronchiolitis obliterans (PIBO) in pediatric patients, and to determine the effect of long-term azithromycin treatment on these factors. In total, 16 cases of children with PIBO were retrospectively reviewed. Adenovirus and Mycoplasma pneumoniae were the most common etiological agents (12/16) in the children with PIBO. The patients presented with persistent dyspnea, a chronic cough, sputum production and wheezing following the initial lung infection...
June 2015: Experimental and Therapeutic Medicine
Jin-Rong Liu, Xue-Feng Xu, Chun-Ju Zhou, Hai-Ming Yang, Shun-Ying Zhao
The most common causes of bronchiolitis obliterans organizing pneumonia (BOOP) are connective tissue diseases, organ transplantation, drug reaction, and infections. Although rare, BOOP due to gastroesophageal reflux (GER) has been reported in adults but not to date in pediatric patients. This study describes 2 pediatric patients who developed GER and BOOP. One patient had superior mesenteric artery syndrome and Helicobacter pylori infection, and the other had a gastroduodenal ulcer with reflux esophagitis. Respiratory symptoms occurred concurrently or after gastrointestinal symptoms...
June 2015: Pediatrics
H M Yoon, J S Lee, J-Y Hwang, Y A Cho, H-K Yoon, J Yu, S-J Hong, C H Yoon
OBJECTIVE: Intravenous pulse methylprednisolone therapy (IPMT) is an important treatment option for post-infectious obliterative bronchiolitis (OB), although it must be used carefully and only in selected patients because of its drawbacks. This study evaluated whether CT and clinical features of children with post-infectious OB can predict their responsiveness to IPMT. METHODS: We searched the medical records for patients (less than 18 years of age) who were diagnosed with post-infectious OB between January 2000 and December 2011...
May 2015: British Journal of Radiology
Alejandro J Colom, Alberto Maffey, Facundo Garcia Bournissen, Alejandro Teper
BACKGROUND: Postinfectious bronchiolitis obliterans (BO) is a chronic respiratory disease that usually follows a severe adenovirus infection. OBJECTIVE: To determine the evolution of pulmonary function and clinical outcome of children with postinfectious BO during childhood. METHODS: The study included patients diagnosed with postinfectious BO in whom at least two spirometries were performed within a minimum interval of 3 months. RESULTS: 46 met the inclusion criteria...
February 2015: Thorax
Ya-Nan Li, Li Liu, Hong-Mei Qiao, Hang Cheng, Huan-Ji Cheng
BACKGROUND: This study aimed to describe the clinical characteristics, radiological features and outcomes of 42 children with post-infectious bronchiolitis obliterans (PIBO). METHODS: Forty-two children diagnosed with PIBO were prospectively studied at the First Hospital of Jilin University in northern China between January, 2008 and January, 2013. Their clinical characteristics, lung high resolution computed tomography (HRCT) findings and pulmonary function tests were reported...
September 25, 2014: BMC Pediatrics
Jose A Castro-Rodriguez, Veronica Giubergia, Gilberto B Fischer, Claudio Castaños, Edgar E Sarria, Ramiro Gonzalez, Rita Mattiello, Luis E Vega-Briceño, Patricia Murtagh
UNLABELLED: Postinfectious bronchiolitis obliterans (PIBO) is an infrequent chronic lung that causes irreversible obstruction and, or, obliteration of the smaller airways. This review particularly focuses on more than 30 studies from South America. CONCLUSION: The initial PIBO event occurs in the early years of life and is strongly associated with adenovirus infection and the need for mechanical ventilator support. Treatment requires a multidisciplinary strategy...
September 2014: Acta Paediatrica
J de Blic, A Deschildre, T Chinet
Post-infectious bronchiolitis obliterans (BO) is characterized by inflammatory and fibrotic lesions of small airways following a pulmonary infection and leading to some degree of airway obstruction. It represents a rare cause of chronic obstructive pulmonary disease, and is probably underestimated, especially when the lesions affect small areas of the lungs. The clinical features differ between children and adults. In children, adenovirus is the most frequently involved infectious agent, especially the more virulent serotypes 3, 7 and 21...
February 2013: Revue des Maladies Respiratoires
Gilberto B Fischer, Edgar E Sarria, Rita Mattiello, Helena T Mocelin, Jose A Castro-Rodriguez
Bronchiolitis Obliterans (BO) is an infrequent chronic and obstructive lung disease secondary to an insult to the terminal airway and its surroundings. In children, the most common presentation is the post-infectious variant, closely related to a severe viral infection in the first three years of life. However, the increase in the number of lung and bone-marrow transplants has also been followed by an increase in post-transplant BO. Post-transplant BO is progressive while post-infectious BO does not seem to be, but both forms share some common pathways that result in a characteristic histopathology of bronchiolar obliteration...
December 2010: Paediatric Respiratory Reviews
V Aguerre, C Castaños, H Gonzalez Pena, M Grenoville, P Murtagh
AIM: Postinfectious bronchiolitis obliterans (PIBO) is an infrequent yet potentially severe disorder following acute lower pulmonary infection (ALRI) in children. In infants and young children PIBO have been strongly associated with Adenovirus (Ad). The purpose of this study was to analyze the clinical features and pulmonary function findings in children with PIBO. Cases caused by Ad were compared with cases in which no viral agent was identified. METHODS: Fifty-eight children with PIBO were prospectively studied...
December 2010: Pediatric Pulmonology
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