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H A Boyd
No abstract text is available yet for this article.
September 2017: BJOG: An International Journal of Obstetrics and Gynaecology
(no author information available yet)
BACKGROUND: Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. METHODS: In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries...
May 27, 2017: Lancet
S Fawcus, R C Pattinson, J Moodley, N F Moran, M G Schoon, R E Mhlanga, S Baloyi, E Bekker, G S Gebhardt
Maternal deaths associated with caesarean deliveries (CDs) have been increasing in South Africa over the past decade. The objective of this report is to bring national attention to this increasing epidemic of maternal deaths due to bleeding associated with CD in the majority of provinces of the country. Individual chart reviews of women who died from bleeding at or after CD show that 71% had avoidable factors. Among the steps we can take are to improve surgical skills and experience, especially in rural hospitals, to improve clinical observations in the immediate postoperative period and in the postnatal wards, and to ensure that appropriate oxytocic agents are given to prevent postpartum haemorrhage...
April 7, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Eric Jauniaux
No abstract text is available yet for this article.
February 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Meredith M Howley, Tonia C Carter, Marilyn L Browne, Paul A Romitti, Christopher M Cunniff, Charlotte M Druschel
BACKGROUND: Low-dose fluconazole is used commonly to treat vulvovaginal candidiasis, a condition occurring frequently during pregnancy. Conflicting information exists on the association between low-dose fluconazole use among pregnant women and the risk of major birth defects. OBJECTIVE: We used data from the National Birth Defects Prevention Study to examine this association. STUDY DESIGN: The National Birth Defects Prevention Study is a multisite, population-based, case-control study that includes pregnancies with estimated delivery dates from 1997 to 2011...
May 2016: American Journal of Obstetrics and Gynecology
Kavita Shah Arora, Larry E Shields, William A Grobman, Mary E D'Alton, Justin R Lappen, Brian M Mercer
The rise in maternal morbidity and mortality has resulted in national and international attention at optimally organizing systems and teams for pregnancy care. Given that maternal morbidity and mortality can occur unpredictably in any obstetric setting, specialists in general obstetrics and gynecology along with other primary maternal care providers should be integrally involved in efforts to improve the safety of obstetric care delivery. Quality improvement initiatives remain vital to meeting this goal. The evidence-based utilization of triggers, bundles, protocols, and checklists can aid in timely diagnosis and treatment to prevent or limit the severity of morbidity as well as facilitate interdisciplinary, patient-centered care...
April 2016: American Journal of Obstetrics and Gynecology
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