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8 papers 0 to 25 followers DVT
D P Goel, R Buckley, G deVries, G Abelseth, A Ni, R Gray
The incidence of deep-vein thrombosis and the need for thromboprophylaxis following isolated trauma below the knee is uncertain. We have investigated this with a prospective randomised double-blind controlled trial using low molecular weight heparin with saline injection as placebo in patients aged between 18 and 75 years who had sustained an isolated fracture below the knee which required operative fixation. All patients had surgery within 48 hours of injury and were randomised to receive either the placebo or low molecular weight heparin for 14 days, after which they underwent bilateral lower limb venography, interpreted by three independent radiologists...
March 2009: Journal of Bone and Joint Surgery. British Volume
S Patil, J Gandhi, I Curzon, A C W Hui
Stable fractures of the ankle can be successfully treated non-operatively by a below-knee plaster cast. In some centres, patients with this injury are routinely administered low-molecular-weight heparin, to reduce the risk of deep-vein thrombosis (DVT). We have assessed the incidence of DVT in 100 patients in the absence of any thromboprophylaxis. A colour Doppler duplex ultrasound scan was done at the time of the removal of the cast. Five patients did develop DVT, though none had clinical signs suggestive of it...
October 2007: Journal of Bone and Joint Surgery. British Volume
Liv Riisager Wahlsten, Henrik Eckardt, Stig Lyngbæk, Per Føge Jensen, Emil Loldrup Fosbøl, Christian Torp-Pedersen, Gunnar Hilmar Gislason, Jonas Bjerring Olesen
BACKGROUND: Our aims were to determine the incidence of symptomatic deep venous thrombosis (DVT) and pulmonary embolism (PE) that required inpatient or outpatient treatment, and to identify specific risk factors associated with DVT/PE in patients who had undergone surgery for a fracture distal to the knee. METHODS: Using individual linkage of nationwide registries, we included all Danish patients who had undergone surgery for a fracture distal to the knee between 1999 and 2011...
March 18, 2015: Journal of Bone and Joint Surgery. American Volume
Alireza Manafi Rasi, Gholamhossein Kazemian, Mohammad Emami Moghadam, Reza Tavakoli Larestani, Amirhossein Fallahi, Ali Nemati, Maryam Nazari, Fateme Fallahi, Saeed Safari
BACKGROUND: There is controversy regarding routine prophylaxis for deep vein thrombosis (DVT) in patients treated via a short leg cast or splint following lower extremity trauma. OBJECTIVES: The main aim of this study is to evaluate the incidence of DVT and need for chemoprophylaxis in these patients. MATERIALS AND METHODS: Patients with ankle sprains or stable foot/ankle fractures were entered in this cross-sectional study. Serum D-dimer levels were measured 2 weeks following fixation...
2013: Trauma Monthly
Rita Selby, William H Geerts, Hans J Kreder, Mark A Crowther, Lisa Kaus, Faith Sealey
BACKGROUND: Among patients with isolated below-knee fractures, previous studies have detected asymptomatic deep vein thrombosis in 10%-40% using contrast venography. However, the clinical relevance of these thrombi is unknown; there is considerable uncertainty about the risk: benefit of routine thromboprophylaxis and clinical practice guidelines differ in their recommendations. METHODS: In this multicenter, double-blind trial, 265 patients with isolated lower leg fractures requiring surgery were randomized to subcutaneous dalteparin 5000 units or matching placebo once daily for 2 weeks with bilateral Doppler ultrasound (DUS) of the proximal leg veins on postoperative day 14±2 and 3-month follow-up...
May 2015: Journal of Orthopaedic Trauma
Hafiz Javaid Iqbal, Raef Dahab, Simon Barnes
BACKGROUND: Ankle fractures are one of the commonest orthopaedic injuries. A substantial proportion of these are treated non-operatively at outpatient clinics with cast immobilization. We conducted this survey to assess the current practice in UK regarding thromboembolism prophylaxis in these patients. METHODS: A telephonic survey was carried out on junior doctors within orthopaedic departments of 56 hospitals across the UK. A questionnaire was completed regarding venous thromboembolism risk assessment, prophylaxis, hospital guidelines, etc...
September 2012: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Lasse J Lapidus, Sari Ponzer, Anders Elvin, Catharina Levander, Gerd Lärfars, Stefan Rosfors, Edin de Bri
BACKGROUND: Skeletal trauma and immobilization are well-known risk factors for deep vein thrombosis (DVT) and pulmonary embolism (PE). While prophylaxis against thromboembolic complications has become routine after major orthopedic surgery, whether or not prophylaxis after minor surgery and lower limb immobilization is necessary is still under debate. METHODS: In a double-blind, placebo-controlled study, 272 consecutive patients were randomized to receive either thromboprophylaxis with Dalteparin (n = 136) or placebo (n = 136) for 5 weeks after ankle fracture surgery...
August 2007: Acta Orthopaedica
Rita Selby, William H Geerts, Hans J Kreder, Mark A Crowther, Lisa Kaus, Faith Sealey
BACKGROUND: The prevalence of deep vein thrombosis as demonstrated by routine venography in patients with distal lower-extremity injury requiring cast immobilization or surgery is 10% to 40%. These deep vein thromboses are usually asymptomatic and distal, and the need for thromboprophylaxis in these patients is not known. METHODS: We conducted a multicenter prospective cohort study to define the prevalence of symptomatic venous thromboembolism in patients with a tibial, fibular, or ankle fracture (treated nonoperatively) or a patellar or foot fracture (treated operatively or conservatively)...
May 21, 2014: Journal of Bone and Joint Surgery. American Volume
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