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https://www.readbyqxmd.com/read/27886895/update-on-idiopathic-intracranial-hypertension
#1
REVIEW
Michael Wall
Idiopathic intracranial hypertension (IIH) is a disorder of elevated intracranial pressure of unknown cause occurring predominantly in young women of childbearing age. The typical patient symptom profile is the presence of daily headache, pulse synchronous tinnitus, transient visual obscurations, and papilledema with its associated visual loss. Although surgical procedures are performed for those who fail medical therapy, their relative efficacy remains unclear. The main morbidity of IIH is from visual loss...
February 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/27660695/update-on-the-treatment-of-type-2-diabetes-mellitus
#2
REVIEW
Juan José Marín-Peñalver, Iciar Martín-Timón, Cristina Sevillano-Collantes, Francisco Javier Del Cañizo-Gómez
To achieve good metabolic control in diabetes and keep long term, a combination of changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal glycated hemoglobin significantly, decreases risk of macrovascular and microvascular complications. At present there are different treatments, both oral and injectable, available for the treatment of type 2 diabetes mellitus (T2DM). Treatment algorithms designed to reduce the development or progression of the complications of diabetes emphasizes the need for good glycaemic control...
September 15, 2016: World Journal of Diabetes
https://www.readbyqxmd.com/read/27766049/management-of-venous-thromboembolism-an-update
#3
REVIEW
Siavash Piran, Sam Schulman
Venous thromboembolism (VTE), which constitutes pulmonary embolism and deep vein thrombosis, is a common disorder associated with significant morbidity and mortality. Landmark trials have shown that direct oral anticoagulants (DOACs) are as effective as conventional anticoagulation with vitamin K antagonists (VKA) in prevention of VTE recurrence and associated with less bleeding. This has paved the way for the recently published guidelines to change their recommendations in favor of DOACs in acute and long-term treatment of VTE in patients without cancer...
2016: Thrombosis Journal
https://www.readbyqxmd.com/read/22287700/medical-management-of-hepatorenal-syndrome
#4
REVIEW
Andrew Davenport, Jawad Ahmad, Ali Al-Khafaji, John A Kellum, Yuri S Genyk, Mitra K Nadim
Hepatorenal syndrome (HRS) is defined as the occurrence of renal dysfunction in a patient with end-stage liver cirrhosis in the absence of another identifiable cause of renal failure. The prognosis of HRS remains poor, with a median survival without liver transplantation of <6 months. However, understanding the pathogenesis of HRS has led to the introduction of treatments designed to increase renal perfusion and mean arterial blood pressure using vasopressors and albumin, which has led to improvement in renal function in ∼50% of patients...
January 2012: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27923816/what-s-new-in-the-2016-esc-guidelines-on-atrial-fibrillation
#5
Dipak Kotecha, Paulus Kirchhof
No abstract text is available yet for this article.
October 7, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27999003/diabetic-neuropathy-a-position-statement-by-the-american-diabetes-association
#6
REVIEW
Rodica Pop-Busui, Andrew J M Boulton, Eva L Feldman, Vera Bril, Roy Freeman, Rayaz A Malik, Jay M Sosenko, Dan Ziegler
No abstract text is available yet for this article.
January 2017: Diabetes Care
https://www.readbyqxmd.com/read/27979889/2-classification-and-diagnosis-of-diabetes
#7
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Diabetes Care
https://www.readbyqxmd.com/read/27880878/neurocysticercosis-infection-and-disease-a-review
#8
REVIEW
Lucy B Gripper, Susan C Welburn
Neurocysticercosis (NCC) is the most common parasitic disease of the human central nervous system (CNS), a pleomorphic disease with a diverse array of clinical manifestations. The infection is pleomorphic and dependent on a complex range of interconnecting factors, including number and size of the cysticerci, their stage of development and localisation within the brain with resulting difficulties in accurate diagnosis and staging of the disease. This review examines the factors that contribute to the accurate assessment of NCC distribution and transmission that are critical to achieving robust disease burden calculations...
February 2017: Acta Tropica
https://www.readbyqxmd.com/read/25524603/sporadic-late-onset-nemaline-myopathy-in-a-woman-with-multiple-myeloma-successfully-treated-with-lenalidomide-dexamethasone
#9
LETTER
Federica Montagnese, Simona Portaro, Olimpia Musumeci, Alba Migliorato, Maurizio Moggio, Gigliola Fagiolari, Carmelo Rodolico
No abstract text is available yet for this article.
June 2015: Muscle & Nerve
https://www.readbyqxmd.com/read/26948435/guillain-barr%C3%A3-syndrome
#10
REVIEW
Hugh J Willison, Bart C Jacobs, Pieter A van Doorn
Guillain-Barré syndrome is the most common and most severe acute paralytic neuropathy, with about 100,000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barré syndrome are several recognisable variants with distinct clinical and pathological features. The severe, generalised manifestation of Guillain-Barré syndrome with respiratory failure affects 20-30% of cases. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care...
August 13, 2016: Lancet
https://www.readbyqxmd.com/read/26886206/clinical-features-pathogenesis-and-treatment-of-myasthenia-gravis-a-supplement-to-the-guidelines-of-the-german-neurological-society
#11
REVIEW
Nico Melzer, Tobias Ruck, Peter Fuhr, Ralf Gold, Reinhard Hohlfeld, Alexander Marx, Arthur Melms, Björn Tackenberg, Berthold Schalke, Christiane Schneider-Gold, Fritz Zimprich, Sven G Meuth, Heinz Wiendl
Myasthenia gravis (MG) is an autoimmune antibody-mediated disorder of neuromuscular synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and weakness affecting ocular, bulbar and (proximal) limb skeletal muscle groups. MG may either occur as an autoimmune disease with distinct immunogenetic characteristics or as a paraneoplastic syndrome associated with tumors of the thymus. Impairment of central thymic and peripheral self-tolerance mechanisms in both cases is thought to favor an autoimmune CD4(+) T cell-mediated B cell activation and synthesis of pathogenic high-affinity autoantibodies of either the IgG1 and 3 or IgG4 subclass...
August 2016: Journal of Neurology
https://www.readbyqxmd.com/read/26958738/zika-virus-associated-with-meningoencephalitis
#12
LETTER
Guillaume Carteaux, Marianne Maquart, Alexandre Bedet, Damien Contou, Pierre Brugières, Slim Fourati, Laurent Cleret de Langavant, Thomas de Broucker, Christian Brun-Buisson, Isabelle Leparc-Goffart, Armand Mekontso Dessap
No abstract text is available yet for this article.
April 21, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/26959308/zika-virus-as-a-cause-of-neurologic-disorders
#13
Nathalie Broutet, Fabienne Krauer, Maurane Riesen, Asheena Khalakdina, Maria Almiron, Sylvain Aldighieri, Marcos Espinal, Nicola Low, Christopher Dye
Zika virus infections have been known in Africa and Asia since the 1940s, but the virus’s geographic range has expanded dramatically since 2007. Between January 1, 2007, and March 1, 2016, local transmission was reported in an additional 52 countries and territories, mainly in the Americas and the..
April 21, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/26857957/teaching-neuroimages-leukodystrophy-and-progressive-myoclonic-epilepsy-disclosing-drpla
#14
EDITORIAL
Paulo Victor Sgobbi de Souza, Gabriel Novaes de Rezende Batistella, Wladimir Bocca Vieira de Rezende Pinto, Acary Souza Bulle Oliveira
No abstract text is available yet for this article.
February 9, 2016: Neurology
https://www.readbyqxmd.com/read/26880813/teaching-neuroimages-red-forehead-dot-syndrome-and-migraine-revisited
#15
LETTER
Bernadette M Monaghan, Shane Smyth
No abstract text is available yet for this article.
February 16, 2016: Neurology
https://www.readbyqxmd.com/read/26692392/antibody-mediated-autoimmune-encephalopathies-and-immunotherapies
#16
REVIEW
Matteo Gastaldi, Anaïs Thouin, Angela Vincent
Over the last 15 years it has become clear that rare but highly recognizable diseases of the central nervous system (CNS), including newly identified forms of limbic encephalitis and other encephalopathies, are likely to be mediated by antibodies (Abs) to CNS proteins. The Abs are directed against membrane receptors and ion channel-associated proteins that are expressed on the surface of neurons in the CNS, such as N-methyl D-aspartate receptors and leucine-rich, glioma inactivated 1 protein and contactin-associated protein like 2, that are associated with voltage-gated potassium channels...
January 2016: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/26705120/myasthenia-gravis-a-clinical-immunological-update
#17
REVIEW
Sophie Binks, Angela Vincent, Jacqueline Palace
Myasthenia gravis (MG) is the archetypic disorder of both the neuromuscular junction and autoantibody-mediated disease. In most patients, IgG1-dominant antibodies to acetylcholine receptors cause fatigable weakness of skeletal muscles. In the rest, a variable proportion possesses antibodies to muscle-specific tyrosine kinase while the remainder of seronegative MG is being explained through cell-based assays using a receptor-clustering technique and, to a lesser extent, proposed new antigenic targets. The incidence and prevalence of MG are increasing, particularly in the elderly...
April 2016: Journal of Neurology
https://www.readbyqxmd.com/read/26609145/chikungunya-virus-associated-encephalitis-a-cohort-study-on-la-r%C3%A3-union-island-2005-2009
#18
Patrick Gérardin, Thérèse Couderc, Marc Bintner, Patrice Tournebize, Michel Renouil, Jérome Lémant, Véronique Boisson, Gianandrea Borgherini, Frédérik Staikowsky, Frédéric Schramm, Marc Lecuit, Alain Michault
OBJECTIVE: To estimate the cumulative incidence rate (CIR) of Chikungunya virus (CHIKV)-associated CNS disease during the La Réunion outbreak, and assess the disease burden and patient outcome after 3 years. METHODS: CHIKV-associated CNS disease was characterized retrospectively in a cohort of patients with positive CHIKV reverse transcriptase PCR or anti-CHIKV immunoglobulin M antibodies in the CSF and fulfilling International Encephalitis Consortium criteria for encephalitis or encephalopathy...
January 5, 2016: Neurology
https://www.readbyqxmd.com/read/26372826/treatment-of-helicobacter-pylori-infection-2015
#19
REVIEW
Anthony O'Connor, Javier P Gisbert, Colm O'Morain, Spiros Ladas
Many interesting articles have been published from many parts of the world over the last year assessing different issues around Helicobacter pylori eradication therapy. This article will address the published literature over the last year pertaining to the topic of treatment of H. pylori infection. The main themes that emerge are assessing the efficacy of standard triple therapy, as well as exploring new first-line treatments, mainly optimized nonbismuth- and bismuth-containing quadruple therapies with some promising data also emerging on dual therapy...
September 2015: Helicobacter
https://www.readbyqxmd.com/read/25971722/diaphragm-ultrasound-in-amyotrophic-lateral-sclerosis-and-other-neuromuscular-disorders
#20
EDITORIAL
Neil G Simon, Matthew C Kiernan
No abstract text is available yet for this article.
January 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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