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Neuropathic Pain literature

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40 papers 25 to 100 followers
By Andreas Tarnaris Consultant Neurosurgeon
https://www.readbyqxmd.com/read/28416992/sphenopalatine-ganglion-block-for-relieving-postdural-puncture-headache-technique-and-mechanism-of-action-of-block-with-a-narrative-review-of-efficacy
#1
REVIEW
Abhijit S Nair, Basanth Kumar Rayani
The sphenopalatine ganglion (SPG) is a parasympathetic ganglion, located in the pterygopalatine fossa. The SPG block has been used for a long time for treating headaches of varying etiologies. For anesthesiologists, treating postdural puncture headaches (PDPH) has always been challenging. The epidural block patch (EBP) was the only option until researchers explored the role of the SPG block as a relatively simple and effective way to treat PDPH. Also, since the existing evidence proving the efficacy of the SPG block in PDPH is scarce, the block cannot be offered to all patients...
April 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28527055/cluster-headache-present-and-future-therapy
#2
Massimo Leone, Alessandro Giustiniani, Alberto Proietti Cecchini
Cluster headache is characterized by severe, unilateral headache attacks of orbital, supraorbital or temporal pain lasting 15-180 min accompanied by ipsilateral lacrimation, rhinorrhea and other cranial autonomic manifestations. Cluster headache attacks need fast-acting abortive agents because the pain peaks very quickly; sumatriptan injection is the gold standard acute treatment. First-line preventative drugs include verapamil and carbolithium. Other drugs demonstrated effective in open trials include topiramate, valproic acid, gabapentin and others...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28267062/allodynia-in-cluster-headache
#3
Leopoldine A Wilbrink, Mark A Louter, Onno P M Teernstra, Erik W van Zwet, Frank J P M Huygen, Joost Haan, Michel D Ferrari, Gisela M Terwindt
Cutaneous allodynia is an established marker for central sensitization in migraine. There is debate whether cutaneous allodynia may also occur in cluster headache, another episodic headache disorder. Here, we examined the presence and severity of allodynia in a large well-defined nationwide population of people with cluster headache. Using validated questionnaires we assessed, cross-sectionally, ictal allodynia and comorbid depression and migraine in the nationwide "Leiden University Cluster headache neuro-Analysis" (LUCA) study...
June 2017: Pain
https://www.readbyqxmd.com/read/28328575/predictors-and-social-consequences-of-daily-pain-expectancy-among-adults-with-chronic-pain
#4
Chung Jung Mun, Kirti Thummala, Mary C Davis, Paul Karoly, Howard Tennen, Alex J Zautra
Previous research suggests that for people living with chronic pain, pain expectancy can undermine access to adaptive resources and functioning. We tested and replicated the unique effect of pain expectancy on subsequent pain through 2 daily diary studies. We also extended previous findings by examining cognitive and affective antecedents of pain expectancy and the consequences of pain expectancy for daily social enjoyment and stress. In study 1, 231 individuals with rheumatoid arthritis completed 30 end-of-day diaries...
July 2017: Pain
https://www.readbyqxmd.com/read/28394850/the-pain-course-a-randomised-controlled-trial-comparing-a-remote-delivered-chronic-pain-management-program-when-provided-in-online-and-workbook-formats
#5
B F Dear, M Gandy, E Karin, T Ricciardi, V J Fogliati, S McDonald, L G Staples, K Nicholson Perry, L Sharpe, M K Nicholas, N Titov
This study compared a remote-delivered pain management program, the Pain Course, when delivered in online and workbook formats. Participants (n = 178) were randomised into 2 groups: (1) an Internet Group (n = 84) who were provided with secure accounts to the program in an online format; or (2) a Workbook Group (n = 94) who were mailed workbook versions of the program. The content of both programs was identical and comprised 5 core lessons, which participants were encouraged to work through over an 8-week period, according to a prescribed timetable...
July 2017: Pain
https://www.readbyqxmd.com/read/28444208/adverse-impacts-of-chronic-pain-on-health-related-quality-of-life-work-productivity-depression-and-anxiety-in-a-community-based-study
#6
Kosuke Kawai, Alison Tse Kawai, Peter Wollan, Barbara P Yawn
Background.: Chronic pain has major clinical and social consequences. Few studies have examined any variation in the extent of impairment on quality of life and work productivity by site and type of chronic pain. Objective.: The objective of our study is to examine adverse impacts of chronic pain on physical and psychological health and work productivity. Methods.: Our community-population study was based on a phone-interview of adults with chronic pain, residing in Olmsted County, MN...
April 22, 2017: Family Practice
https://www.readbyqxmd.com/read/28451808/neuropathic-pain-and-spinal-cord-injury-phenotypes-and-pharmacological-management
#7
REVIEW
Eva Widerström-Noga
Chronic neuropathic pain is a complicated condition after a spinal cord injury (SCI) that often has a lifelong and significant negative impact on life after the injury; therefore, improved pain management is considered a significant and unmet need. Neuropathic pain mechanisms are heterogeneous and the difficulty in determining their individual contribution to specific pain types may contribute to poor treatment outcomes in this population. Thus, identifying human neuropathic pain phenotypes based on pain symptoms, somatosensory changes, or cognitive and psychosocial factors that reflect specific spinal cord or brain mechanisms of neuropathic pain is an important goal...
June 2017: Drugs
https://www.readbyqxmd.com/read/28469663/estrogen-affects-neuropathic-pain-through-upregulating-n-methyl-d-aspartate-acid-receptor-1-expression-in-the-dorsal-root-ganglion-of-rats
#8
Chao Deng, Ya-Juan Gu, Hong Zhang, Jun Zhang
Estrogen affects the generation and transmission of neuropathic pain, but the specific regulatory mechanism is still unclear. Activation of the N-methyl-D-aspartate acid receptor 1 (NMDAR1) plays an important role in the production and maintenance of hyperalgesia and allodynia. The present study was conducted to determine whether a relationship exists between estrogen and NMDAR1 in peripheral nerve pain. A chronic sciatic nerve constriction injury model of chronic neuropathic pain was established in rats. These rats were then subcutaneously injected with 17β-estradiol, the NMDAR1 antagonist D(-)-2-amino-5-phosphonopentanoic acid (AP-5), or both once daily for 15 days...
March 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28263454/neuroplasticity-of-supraspinal-structures-associated-with-pathological-pain
#9
Pere Boadas-Vaello, Judit Homs, Francisco Reina, Ana Carrera, Enrique Verdú
Peripheral nerve and spinal cord injuries, along with other painful syndromes such as fibromyalgia, diabetic neuropathy, chemotherapeutic neuropathy, trigeminal neuralgia, complex regional pain syndrome, and/or irritable bowel syndrome, cause several neuroplasticity changes in the nervous system along its entire axis affecting the different neuronal nuclei. This paper reviews these changes, focusing on the supraspinal structures that are involved in the modulation and processing of pain, including the periaqueductal gray matter, red nucleus, locus coeruleus, rostral ventromedial medulla, thalamus, hypothalamus, basal ganglia, cerebellum, habenula, primary, and secondary somatosensory cortex, motor cortex, mammillary bodies, hippocampus, septum, amygdala, cingulated, and prefrontal cortex...
March 6, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28445862/treatments-of-traumatic-neuropathic-pain-a-systematic-review
#10
Chenglun Yao, Xijie Zhou, Bin Zhao, Chao Sun, Keshav Poonit, Hede Yan
Traumatic neuropathic pain caused by traumatic neuroma has long been bothering both doctors and patients, the mechanisms of traumatic neuropathic pain are widely discussed by researchers and the treatment is challenging. Clinical treatment of painful neuroma is unclear. Numerous treatment modalities have been introduced by experts in this field. However, there is still no single standard recognized treatment.Different forms of treatments have been tested in animals and humans, but pharmacotherapies (antidepressants, antiepileptics) remain the basis of traumatic neuropathic pain management...
April 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28403646/neuropathic-orofacial-pain-facts-and-fiction
#11
Lene Baad-Hansen, Rafael Benoliel
Definition and taxonomy This review deals with neuropathic pain of traumatic origin affecting the trigeminal nerve, i.e. painful post-traumatic trigeminal neuropathy (PTTN). Symptomatology The clinical characteristics of PTTN vary considerably, partly due to the type and extent of injury. Symptoms involve combinations of spontaneous and evoked pain and of positive and negative somatosensory signs. These patients are at risk of going through unnecessary dental/surgical procedures in the attempt to eradicate the cause of the pain, due to the fact that most dentists only rarely encounter PTTN...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28425324/persistent-idiopathic-facial-pain
#12
Rafael Benoliel, Charly Gaul
Background Persistent idiopathic facial pain (PIFP) is a chronic disorder recurring daily for more than two hours per day over more than three months, in the absence of clinical neurological deficit. PIFP is the current terminology for Atypical Facial Pain and is characterized by daily or near daily pain that is initially confined but may subsequently spread. Pain cannot be attributed to any pathological process, although traumatic neuropathic mechanisms are suspected. When present intraorally, PIFP has been termed 'Atypical Odontalgia', and this entity is discussed in a separate article in this special issue...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28432602/sphenopalatine-ganglion-block-in-the-management-of-chronic-headaches
#13
REVIEW
Jeffery Mojica, Bi Mo, Andrew Ng
PURPOSE OF REVIEW: Sphenopalatine ganglion (SPG) block has been used by clinicians in the treatment of a variety of headache disorders, facial pain syndromes, and other facial neuralgias. The sensory and autonomic fibers that travel through the SPG provided the scientific rationale for symptoms associated with these head and neck syndromes. Yet, despite the elucidation of this pathogenic target, the optimal method to block its pain-producing properties has not been determined. Clinicians have developed various invasive and non-invasive techniques, each of which has shown variable rates of success...
June 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27038972/new-chronic-pain-treatments-in-the-outpatient-setting-review-article
#14
REVIEW
R Grandhe, D Souzdalnitski, K Gritsenko
Chronic pain is an issue encountered by many health care providers in their routine clinical practice. In addition to generalized patient suffering, this condition has significant clinical, psychological, and socioeconomic impact due to its widespread occurrence. The landscape of chronic pain management has been changing rapidly with an array of treatment innovations, better understanding of established therapies, and care coordination across specialties. In this article, we have reviewed emerging new modalities as well as transformation of established therapies by interventional, pharmacologic, rehabilitative, psychological, complimentary, and interdisciplinary approaches...
May 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27341614/neuropathic-pain-prevalence-following-spinal-cord-injury-a-systematic-review-and-meta-analysis
#15
REVIEW
D Burke, B M Fullen, D Stokes, O Lennon
Following spinal cord injury (SCI), chronic pain is a common secondary complication with neuropathic pain (NP) cited as one of the most distressing and debilitating conditions leading to poor quality of life, depression and sleep disturbances. Neuropathic pain presenting at or below the level of injury is largely refractory to current pharmacological and physical treatments. No consensus on the prevalence of NP post SCI currently exists, hence this systematic review was undertaken. The review comprised three phases: a methodological assessment of databases [PubMed, Embase, Web of Knowledge, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library and Physiotherapy Evidence Database (PEDro)] identifying potential papers and screening for inclusion criteria by two independent reviewers; data extraction; and finally rating of internal validity and strength of the evidence, using a published valid and reliable scale...
January 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27115670/neuropathic-pain-an-updated-grading-system-for-research-and-clinical-practice
#16
REVIEW
Nanna B Finnerup, Simon Haroutounian, Peter Kamerman, Ralf Baron, David L H Bennett, Didier Bouhassira, Giorgio Cruccu, Roy Freeman, Per Hansson, Turo Nurmikko, Srinivasa N Raja, Andrew S C Rice, Jordi Serra, Blair H Smith, Rolf-Detlef Treede, Troels S Jensen
The redefinition of neuropathic pain as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system," which was suggested by the International Association for the Study of Pain (IASP) Special Interest Group on Neuropathic Pain (NeuPSIG) in 2008, has been widely accepted. In contrast, the proposed grading system of possible, probable, and definite neuropathic pain from 2008 has been used to a lesser extent. Here, we report a citation analysis of the original NeuPSIG grading paper of 2008, followed by an analysis of its use by an expert panel and recommendations for an improved grading system...
August 2016: Pain
https://www.readbyqxmd.com/read/27175563/systematic-review-of-central-post-stroke-pain-what-is-happening-in-the-central-nervous-system
#17
Gulseren Akyuz, Pinar Kuru
Central poststroke pain (CPSP) is one of the most common central neuropathic pain syndromes seen after stroke. It is mainly related with vascular damage at certain brain territory and pain related to corresponding body areas. In the past, it was described as one of the definitive symptoms of thalamic lesion. However, recent findings suggest that it is not only seen after thalamic lesions but also seen after vascular lesions in any part of the central nervous system. Although there are certain hypotheses to explain physiopathologic mechanisms of CPSP, further evidence is needed...
August 2016: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/27093432/symptom-profiles-in-the-paindetect-questionnaire-in-patients-with-peripheral-neuropathic-pain-stratified-according-to-sensory-loss-in-quantitative-sensory-testing
#18
Jan Vollert, Martin Kramer, Alejandro Barroso, Rainer Freynhagen, Maija Haanpää, Per Hansson, Troels S Jensen, Bianca M Kuehler, Christoph Maier, Tina Mainka, Maren Reimer, Märta Segerdahl, Jordi Serra, Romà Solà, Thomas R Tölle, Rolf-Detlef Treede, Ralf Baron
The painDETECT Questionnaire (PDQ) is commonly used as a screening tool to discriminate between neuropathic pain (NP) and nociceptive pain, based on the self-report of symptoms, including pain qualities, numbness, and pain to touch, cold, or heat. However, there are minimal data about whether the PDQ is differentially sensitive to different sensory phenotypes in NP. The aim of the study was to analyze whether the overall PDQ score or its items reflect phenotypes of sensory loss in NP as determined by quantitative sensory testing...
August 2016: Pain
https://www.readbyqxmd.com/read/26423982/physical-examination-tests-for-screening-and-diagnosis-of-cervicogenic-headache-a-systematic-review
#19
REVIEW
J Rubio-Ochoa, J Benítez-Martínez, E Lluch, S Santacruz-Zaragozá, P Gómez-Contreras, C E Cook
It has been suggested that differential diagnosis of headaches should consist of a robust subjective examination and a detailed physical examination of the cervical spine. Cervicogenic headache (CGH) is a form of headache that involves referred pain from the neck. To our knowledge, no studies have summarized the reliability and diagnostic accuracy of physical examination tests for CGH. The aim of this study was to summarize the reliability and diagnostic accuracy of physical examination tests used to diagnose CGH...
February 2016: Manual Therapy
https://www.readbyqxmd.com/read/27028915/opioid-abuse-in-chronic-pain-misconceptions-and-mitigation-strategies
#20
REVIEW
Nora D Volkow, A Thomas McLellan
No abstract text is available yet for this article.
March 31, 2016: New England Journal of Medicine
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