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Spinal Cord Stimulation literature

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14 papers 25 to 100 followers
By Andreas Tarnaris Consultant Neurosurgeon
David A Provenzano, Jared Rebman, Cody Kuhel, Hilary Trenz, Jason Kilgore
OBJECTIVES: Methods of energy delivery for traditional spinal cord stimulation (SCS) systems consist of adjusting programming parameters to affect the total charge delivered per unit time. One high electrical charge delivery method being considered is subthreshold high density (HD) programming. To date, there is limited clinical evidence for the efficacy and safety of paresthesia-free HD programming. The aim of this study was to examine the efficacy and safety of HD programming. MATERIALS AND METHODS: A retrospective review was performed on HD-programmed SCS patients with a minimum of one year follow-up...
May 25, 2017: Neuromodulation: Journal of the International Neuromodulation Society
Susan M Moeschler, Nafisseh S Warner, Tim J Lamer, Markus A Bendel, Matthew A Warner, Jason S Eldrige, William D Mauck, Halena M Gazelka, Daryl J Kor, Bryan C Hoelzer
INTRODUCTION: Spinal cord stimulators (SCS) are indicated for the management of multiple pain states with strong evidence. Recent guidelines recommend discontinuing aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) for the described procedures. The goal of this investigation is to assess the rate of bleeding and neurologic sequelae in patients undergoing SCS trials and implantation. METHODS: This is a retrospective review from 2005 through 2014 of all patients 18 years or older undergoing the following procedures: Percutaneous SCS implantations, SCS revisions, and SCS trials...
November 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Emerson Magno de Andrade, Maria Gabriela Ghilardi, Rubens Gisbert Cury, Egberto Reis Barbosa, Romulo Fuentes, Manoel Jacobsen Teixeira, Erich Talamoni Fonoff
Axial symptoms are a late-developing phenomenon in the course of Parkinson's disease (PD) and represent a therapeutic challenge given their poor response to levodopa therapy and deep brain stimulation. Spinal cord stimulation (SCS) may be a new therapeutic approach for the alleviation of levodopa-resistant motor symptoms of PD. Our purpose was to systematically review the effectiveness of SCS for the treatment of motor symptoms of PD and to evaluate the technical and pathophysiological mechanisms that may influence the outcome efficacy of SCS...
January 2016: Neurosurgical Review
Joseph Rabi, Magdalena Anitescu
UNLABELLED: The objective of this manuscript was to report a case of a patient with extruded pulse generator 3 years after implantation of a spinal cord stimulator system.With the increasing incidence of chronic pain, spinal cord stimulation (SCS) is becoming more commonly utilized by pain physicians. SCS is a generally safe intervention with minimal adverse effects; however, there are risks of complications which practitioners should be aware of prior to and after placement of the SCS...
2016: Pain Physician
R Nardone, Y Höller, P B Langthaler, P Lochner, S Golaszewski, K Schwenker, F Brigo, E Trinka
STUDY DESIGN: Repetitive transcranial magnetic stimulation study. OBJECTIVES: The analgesic effects of repetitive transcranial magnetic stimulation (rTMS) in chronic pain have been the focus of several studies. In particular, rTMS of the premotor cortex/dorsolateral prefrontal cortex (PMC/DLPFC) changes pain perception in healthy subjects and has analgesic effects in acute postoperative pain, as well as in fibromyalgia patients. However, its effect on neuropathic pain in patients with traumatic spinal cord injury (SCI) has not been assessed...
January 2017: Spinal Cord
Rocco Salvatore Calabrò, Antonino Naro, Antonino Leo, Placido Bramanti
CONTEXT: Spinal cord injury (SCI) affects more than 2.5 million people worldwide, often leading to severe disability. Thus, a proper management of individuals with SCI is required either in the acute or in the post-acute rehabilitative phase. FINDINGS: A 31-year-old man, affected by chronic SCI, underwent two different intensive rehabilitation treatments, including either LokomatPro or a paired LokomatPro-rTMS training. We evaluated the clinical, kinetic, and electrophysiological parameters before and after each training session...
January 2017: Journal of Spinal Cord Medicine
Rajivan Maniam, Alan David Kaye, Nalini Vadivelu, Richard D Urman
Craniofacial pain, including trigeminal neuralgia, trigeminal neuropathic pain, and persistent idiopathic facial pain, is difficult to treat and can have severe implications for suffering in patients afflicted with these conditions. In recent years, clinicians have moved beyond treating solely with pharmacological therapies, which are generally not very effective, and focused on new interventional pain procedures. These procedures have evolved as technology has advanced, and thus far, early results have demonstrated efficacy in small patient cohorts with a variety of craniofacial pain states...
April 2016: Current Pain and Headache Reports
Paolo Barbaresi, Emanuela Mensà
Electrical stimulation of the dorsal columns (DCs; spinal cord stimulation; SCS) has been proposed to treat chronic neuropathic pain. SCS may activate a dual mechanism that would affect both the spinal cord and supraspinal levels. Stimulation of DCs or DC nuclei (DCN) in animals where neuropathic pain has been induced causes activation of brainstem centers including the periaqueductal gray (PAG), which is involved in the endogenous pain suppression system. Biotinylated dextran-amine (BDA) was iontophoretically injected into the DCN to analyze the ascending projection directed to the PAG...
August 2016: Neuroscience Research
Anne-Li Lind, Di Wu, Eva Freyhult, Constantin Bodolea, Titti Ekegren, Anders Larsson, Mats G Gustafsson, Lenka Katila, Jonas Bergquist, Torsten Gordh, Ulf Landegren, Masood Kamali-Moghaddam
The objective of this study was to develop and apply a novel multiplex panel of solid-phase proximity ligation assays (SP-PLA) requiring only 20 μL of samples, as a tool for discovering protein biomarkers for neurological disease and treatment thereof in cerebrospinal fluid (CSF). We applied the SP-PLA to samples from two sets of patients with poorly understood nervous system pathologies amyotrophic lateral sclerosis (ALS) and neuropathic pain, where patients were treated with spinal cord stimulation (SCS)...
2016: PloS One
Shivanand P Lad, Frank W Petraglia, Alexander R Kent, Steven Cook, Kelly R Murphy, Nirav Dalal, Edward Karst, Peter Staats, Ashwini Sharan
INTRODUCTION: A shorter delay time from chronic pain diagnosis to spinal cord stimulation (SCS) implantation may make it more likely to achieve lasting therapeutic efficacy with SCS. The objective of this analysis was to determine the impact of pain-to-SCS time on patients' post-implant healthcare resource utilization (HCRU). METHODS: A retrospective observational study was performed using a real-world patient cohort derived from MarketScan(®) Commercial and Medicare Supplemental claims data bases from April 2008 through March 2013...
July 2016: Neuromodulation: Journal of the International Neuromodulation Society
Andrew K Chan, Ethan A Winkler, Line Jacques
OBJECTIVE Cervical spinal cord stimulation (cSCS) is used to treat pain of the cervical region and upper extremities. Case reports and small series have shown a relatively low risk of complication after cSCS, with only a single reported case of perioperative spinal cord injury in the literature. Catastrophic cSCS-associated spinal cord injury remains a concern as a result of underreporting. To aid in preoperative counseling, it is necessary to establish a minimum rate of spinal cord injury and surgical complication following cSCS...
July 2016: Journal of Neurosurgery. Spine
David A Provenzano, Timothy Deer, Amy Luginbuhl Phelps, Zachary C Drennen, Simon Thomson, Salim M Hayek, Samer Narouze, Maunak V Rana, Tyler W Watson, Asokumar Buvanendran
OBJECTIVES: Surgical site infections (SSIs) are associated with significant healthcare costs and morbidity. Limited research exists specific to the prevention of spinal cord stimulation (SCS) SSIs. The objectives of this international survey were to examine current infection control practices for SCS trials and implants and to compare reported responses with evidence-based recommendations. MATERIALS AND METHODS: A 33-question survey was developed based on an extensive literature review for infection control policies...
January 2016: Neuromodulation: Journal of the International Neuromodulation Society
Milind Deogaonkar, Mayur Sharma, Chima Oluigbo, Dylan M Nielson, Xiangyu Yang, Louis Vera-Portocarrero, Gregory F Molnar, Amir Abduljalil, Per B Sederberg, Michael Knopp, Ali R Rezai
INTRODUCTION: The neurophysiological basis of pain relief due to spinal cord stimulation (SCS) and the related cortical processing of sensory information are not completely understood. The aim of this study was to use resting state functional magnetic resonance imaging (rs-fMRI) to detect changes in cortical networks and cortical processing related to the stimulator-induced pain relief. METHODS: Ten patients with complex regional pain syndrome (CRPS) or neuropathic leg pain underwent thoracic epidural spinal cord stimulator implantation...
February 2016: Neuromodulation: Journal of the International Neuromodulation Society
L D Bentley, R V Duarte, P L Furlong, R L Ashford, J H Raphael
BACKGROUND AND OBJECTIVE: Spinal cord stimulation (SCS) is believed to exert supraspinal effects; however, these mechanisms are still far from fully elucidated. This systematic review aims to assess existing neurophysiological and functional neuroimaging literature to reveal current knowledge regarding the effects of SCS for chronic neuropathic pain on brain activity, to identify gaps in knowledge, and to suggest directions for future research. DATABASES AND DATA TREATMENT: Electronic databases and hand-search of reference lists were employed to identify publications investigating brain activity associated with SCS in patients with chronic neuropathic pain, using neurophysiological and functional neuroimaging techniques (fMRI, PET, MEG, EEG)...
April 2016: European Journal of Pain: EJP
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