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Spinal Cord Stimulation literature

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25 papers 25 to 100 followers
By Andreas Tarnaris Consultant Neurosurgeon
https://www.readbyqxmd.com/read/29126228/prospective-randomized-blind-effect-on-outcome-study-of-conventional-vs-high-frequency-spinal-cord-stimulation-in-patients-with-pain-and-disability-due-to-failed-back-surgery-syndrome
#1
Jose De Andres, Vicente Monsalve-Dolz, Gustavo Fabregat-Cid, Vicente Villanueva-Perez, Anushik Harutyunyan, Juan Marcos Asensio-Samper, Nerea Sanchis-Lopez
Objectives: Spinal cord stimulation (SCS) for patients with failed back surgery syndrome (FBSS) show variable results and limited to moderate evidence. In the last years the stimulation of high frequency (HF) has been considered as a better alternative in this pathology for its supposed benefits compared to the stimulation with conventional frequency (CF). To compare in one year follow-up, the efficacy of high-frequency SCS (HF) versus conventional frequency SCS (CF) on the patients with FBSS...
November 4, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29224084/bipolar-dual-lead-spinal-cord-stimulation-between-two-electrodes-on-the-ventral-and-dorsal-sides-of-the-spinal-cord-consideration-of-putative-mechanisms
#2
Mitsuru Watanabe, Takamitsu Yamamoto, Chikashi Fukaya, Toshiki Obuchi, Toshikazu Kano, Kazutaka Kobayashi, Hideki Oshima, Atsuo Yoshino
We have applied bipolar dual-lead spinal cord stimulation (SCS) between two cylinder-type electrodes placed on the ventral and dorsal sides of the spinal cord (dual-VD-SCS). A 36-year-old man suffered from burning pain from his right elbow down to his hand after brachial plexus avulsion. The areas with paresthesia induced by conventional SCS did not include the painful hand area. However, dual-VD-SCS completely induced paresthesia in the painful hand area. We speculate that dual-VD-SCS can be applied to stimulate deeper sites of the dorsal column and dorsal horn than conventional SCS and is useful for pain reduction...
December 9, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29244102/association-of-opioid-usage-with-spinal-cord-stimulation-outcomes
#3
Ashwini D Sharan, Jonathan Riley, Steven Falowski, Jason E Pope, Allison T Connolly, Edward Karst, Nirav Dalal, David A Provenzano
Study Design: Observational study using insurance claims. Objective: To quantify opioid usage leading up to spinal cord stimulation (SCS) and the potential impact on outcomes of SCS. Setting: SCS is an interventional therapy that often follows opioid usage in the care continuum for chronic pain. Methods: This study identified SCS patients using the Truven Health MarketScan databases from January 2010 to December 2014...
December 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29249191/burst-and-high-frequency-stimulation-underlying-mechanism-of-action
#4
Shaheen Ahmed, Thomas Yearwood, Dirk De Ridder, Sven Vanneste
Paresthesia-free spinal cord stimulation (SCS) techniques, such as burst and high-frequency (HF) SCS, have been developed and demonstrated to be successful for treating chronic pain, albeit via different mechanisms of action. The goal of this review is to discuss the mechanisms of action for pain suppression at both the cellular and systems levels for burst and HF SCS. In addition, we also discuss the neuromodulation devices that mimic these paradigms. Areas covered: The authors performed a literature review to unravel the mechanisms of action for burst and HF SCS coupled with booklets and user manuals from neuromodulation companies to understand the programmable parameters and operating ranges...
January 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29131488/dorsal-root-ganglion-stimulation-used-for-the-treatment-of-chronic-neuropathic-pain-in-the-groin-a-single-center-study-with-long-term-prospective-results-in-34-cases
#5
Matthias Hubert Morgalla, Anil Bolat, Marcos Fortunato, Guilherme Lepski, Bankim Subhash Chander
OBJECTIVE: Chronic neuropathic pain in the groin is a severe condition and difficult to treat. Dorsal root ganglion stimulation (DRGS) covers discrete painful areas precisely with its stimulation power in comparison to spinal cord stimulation (SCS). It was our hypothesis that DRGS provides a long-term relief of chronic groin pain over a period of more than three years. MATERIALS AND METHODS: Patients (age >18 years) with chronic neuropathic groin pain were prospectively examined...
December 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29139079/neuromodulatory-procedures-for-gait-disorders-in-parkinson-s-disease
#6
REVIEW
Patrick Santens
The neurophysiology of gait is complex and involves numerous structures in the central nervous system. Gait disorders occur frequently in Parkinson's disease (PD), and their management may become cumbersome, especially in the more advanced stages. Neuromodulatory treatments, including deep brain stimulation, cortical stimulation and spinal cord stimulation, are reviewed with respect to their effectiveness to improve gait in PD patients. Although positive effects have been reported for all of these procedures, many issues remain in view of methodological heterogeneity, variability in outcome measures and sample size...
November 14, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29149152/loss-of-efficacy-to-spinal-cord-stimulator-therapy-clinical-evidence-and-possible-causes
#7
Christopher M Aiudi, Roger Y Dunn, Sara M Burns, Sarah A Roth, Arissa Opalacz, Yi Zhang, Lucy Chen, Jianren Mao, Shihab U Ahmed
BACKGROUND: Although spinal cord stimulation (SCS) therapy has been shown to be efficacious in various pain conditions, the ability for SCS therapy to maintain long-term efficacy has been questioned. OBJECTIVE: The purpose of this study was to investigate whether a loss of efficacy (LOE) phenomenon exists with SCS therapy and to investigate if this phenomenon is more apparent in any specific patient population. STUDY DESIGN: A retrospective, observation chart review was conducted to evaluate the patient response to SCS therapy over time...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29038061/structural-and-functional-brain-changes-at-early-and-late-stages-of-complex-regional-pain-syndrome
#8
Mahsa Shokouhi, Collin Clarke, Patricia Morley-Forster, Dwight E Moulin, Karen D Davis, Keith St Lawrence
Brain plasticity is demonstrated in complex regional pain syndrome (CRPS), although it is unclear how it modulates at different stages of CRPS. The observation that symptoms can progress over time suggests that the pattern of brain changes might also evolve. We measured structural and functional changes as well as sensorimotor integration at the early stage (ES) and late stage (LS) of CRPS. Twelve ES patients, 16 LS patients, and 16 age- and sex-matched controls were recruited. Gray matter (GM) volume was estimated using voxel-based morphometry...
October 14, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29077889/long-term-improvements-in-chronic-axial-low-back-pain-patients-without-previous-spinal-surgery-a-cohort-analysis-of-10-khz-high-frequency-spinal-cord-stimulation-over-36%C3%A2-months
#9
Adnan Al-Kaisy, Stefano Palmisani, Thomas E Smith, Roy Carganillo, Russell Houghton, David Pang, William Burgoyne, Khai Lam, Jonathan Lucas
Objective: This prospective, open-label study was designed to evaluate the long-term effectiveness of 10-kHz high-frequency spinal cord stimulation (SCS) in the treatment of chronic axial low back pain with no history of spinal surgery. Methods: Patients with chronic low back pain without previous spinal surgery underwent assessment by a multidisciplinary pain and surgical team to confirm eligibility. After a successful temporary trial of 10-kHz HF-SCS therapy, defined by ≥50% back pain reduction, enrolled subjects underwent permanent system implantation and were followed up for 36 months...
October 24, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28980364/neuropathic-pain-medication-use-does-not-alter-outcomes-of-spinal-cord-stimulation-for-lower-extremity-pain
#10
Dermot P Maher, Yuri Chaves Martins, Tina Doshi, Mark Bicket, Kui Zhang, George Hanna, Shihab Ahmed
INTRODUCTION: Spinal cord stimulation (SCS) for the treatment of lower extremity pain is believed to the result of increased activity in the descending inhibitory and decreased activity in the ascending excitatory tracts. Evidence suggests that the analgesia afforded by SCS may be altered using certain neuropathic pain medications that also modulate neurotransmitters in these sensory tracts. We hypothesize that neuropathic pain medications may alter the response to SCS therapy. METHODS: One hundred and fifteen subjects undergoing SCS therapy for lower extremity pain were retrospectively examined...
October 4, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28961366/success-using-neuromodulation-with-burst-sunburst-study-results-from-a-prospective-randomized-controlled-trial-using-a-novel-burst-waveform
#11
Timothy Deer, Konstantin V Slavin, Kasra Amirdelfan, Richard B North, Allen W Burton, Thomas L Yearwood, Ed Tavel, Peter Staats, Steven Falowski, Jason Pope, Rafael Justiz, Alain Y Fabi, Alexander Taghva, Richard Paicius, Timothy Houden, Derron Wilson
OBJECTIVE: The purpose of the multicenter, randomized, unblinded, crossover success using neuromodulation with BURST (SUNBURST) study was to determine the safety and efficacy of a device delivering both traditional tonic stimulation and burst stimulation to patients with chronic pain of the trunk and/or limbs. METHODS: Following a successful tonic trial, 100 subjects were randomized to receive one stimulation mode for the first 12 weeks, and then the other stimulation mode for the next 12 weeks...
September 29, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28547853/the-efficacy-of-high-density-spinal-cord-stimulation-among-trial-implant-and-conversion-patients-a-retrospective-case-series
#12
David A Provenzano, Jared Rebman, Cody Kuhel, Hilary Trenz, Jason Kilgore
OBJECTIVES: Methods of energy delivery for traditional spinal cord stimulation (SCS) systems consist of adjusting programming parameters to affect the total charge delivered per unit time. One high electrical charge delivery method being considered is subthreshold high density (HD) programming. To date, there is limited clinical evidence for the efficacy and safety of paresthesia-free HD programming. The aim of this study was to examine the efficacy and safety of HD programming. MATERIALS AND METHODS: A retrospective review was performed on HD-programmed SCS patients with a minimum of one year follow-up...
October 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/27296055/bleeding-complications-in-patients-undergoing-percutaneous-spinal-cord-stimulator-trials-and-implantations
#13
Susan M Moeschler, Nafisseh S Warner, Tim J Lamer, Markus A Bendel, Matthew A Warner, Jason S Eldrige, William D Mauck, Halena M Gazelka, Daryl J Kor, Bryan C Hoelzer
INTRODUCTION: Spinal cord stimulators (SCS) are indicated for the management of multiple pain states with strong evidence. Recent guidelines recommend discontinuing aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) for the described procedures. The goal of this investigation is to assess the rate of bleeding and neurologic sequelae in patients undergoing SCS trials and implantation. METHODS: This is a retrospective review from 2005 through 2014 of all patients 18 years or older undergoing the following procedures: Percutaneous SCS implantations, SCS revisions, and SCS trials...
November 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/26219854/spinal-cord-stimulation-for-parkinson-s-disease-a-systematic-review
#14
REVIEW
Emerson Magno de Andrade, Maria Gabriela Ghilardi, Rubens Gisbert Cury, Egberto Reis Barbosa, Romulo Fuentes, Manoel Jacobsen Teixeira, Erich Talamoni Fonoff
Axial symptoms are a late-developing phenomenon in the course of Parkinson's disease (PD) and represent a therapeutic challenge given their poor response to levodopa therapy and deep brain stimulation. Spinal cord stimulation (SCS) may be a new therapeutic approach for the alleviation of levodopa-resistant motor symptoms of PD. Our purpose was to systematically review the effectiveness of SCS for the treatment of motor symptoms of PD and to evaluate the technical and pathophysiological mechanisms that may influence the outcome efficacy of SCS...
January 2016: Neurosurgical Review
https://www.readbyqxmd.com/read/27228537/late-extrusion-of-an-implantable-pulse-generator-of-a-spinal-cord-stimulator
#15
Joseph Rabi, Magdalena Anitescu
UNLABELLED: The objective of this manuscript was to report a case of a patient with extruded pulse generator 3 years after implantation of a spinal cord stimulator system.With the increasing incidence of chronic pain, spinal cord stimulation (SCS) is becoming more commonly utilized by pain physicians. SCS is a generally safe intervention with minimal adverse effects; however, there are risks of complications which practitioners should be aware of prior to and after placement of the SCS...
2016: Pain Physician
https://www.readbyqxmd.com/read/27241450/rtms-of-the-prefrontal-cortex-has-analgesic-effects-on-neuropathic-pain-in-subjects-with-spinal-cord-injury
#16
RANDOMIZED CONTROLLED TRIAL
R Nardone, Y Höller, P B Langthaler, P Lochner, S Golaszewski, K Schwenker, F Brigo, E Trinka
STUDY DESIGN: Repetitive transcranial magnetic stimulation study. OBJECTIVES: The analgesic effects of repetitive transcranial magnetic stimulation (rTMS) in chronic pain have been the focus of several studies. In particular, rTMS of the premotor cortex/dorsolateral prefrontal cortex (PMC/DLPFC) changes pain perception in healthy subjects and has analgesic effects in acute postoperative pain, as well as in fibromyalgia patients. However, its effect on neuropathic pain in patients with traumatic spinal cord injury (SCI) has not been assessed...
January 2017: Spinal Cord
https://www.readbyqxmd.com/read/27077568/usefulness-of-robotic-gait-training-plus-neuromodulation-in-chronic-spinal-cord-injury-a-case-report
#17
Rocco Salvatore Calabrò, Antonino Naro, Antonino Leo, Placido Bramanti
CONTEXT: Spinal cord injury (SCI) affects more than 2.5 million people worldwide, often leading to severe disability. Thus, a proper management of individuals with SCI is required either in the acute or in the post-acute rehabilitative phase. FINDINGS: A 31-year-old man, affected by chronic SCI, underwent two different intensive rehabilitation treatments, including either LokomatPro or a paired LokomatPro-rTMS training. We evaluated the clinical, kinetic, and electrophysiological parameters before and after each training session...
January 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/26896948/facial-pain-update-advances-in-neurostimulation-for-the-treatment-of-facial-pain
#18
REVIEW
Rajivan Maniam, Alan David Kaye, Nalini Vadivelu, Richard D Urman
Craniofacial pain, including trigeminal neuralgia, trigeminal neuropathic pain, and persistent idiopathic facial pain, is difficult to treat and can have severe implications for suffering in patients afflicted with these conditions. In recent years, clinicians have moved beyond treating solely with pharmacological therapies, which are generally not very effective, and focused on new interventional pain procedures. These procedures have evolved as technology has advanced, and thus far, early results have demonstrated efficacy in small patient cohorts with a variety of craniofacial pain states...
April 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/26902642/connections-from-the-rat-dorsal-column-nuclei-dcn-to-the-periaqueductal-gray-matter-pag
#19
Paolo Barbaresi, Emanuela Mensà
Electrical stimulation of the dorsal columns (DCs; spinal cord stimulation; SCS) has been proposed to treat chronic neuropathic pain. SCS may activate a dual mechanism that would affect both the spinal cord and supraspinal levels. Stimulation of DCs or DC nuclei (DCN) in animals where neuropathic pain has been induced causes activation of brainstem centers including the periaqueductal gray (PAG), which is involved in the endogenous pain suppression system. Biotinylated dextran-amine (BDA) was iontophoretically injected into the DCN to analyze the ascending projection directed to the PAG...
August 2016: Neuroscience Research
https://www.readbyqxmd.com/read/26914813/a-multiplex-protein-panel-applied-to-cerebrospinal-fluid-reveals-three-new-biomarker-candidates-in-als-but-none-in-neuropathic-pain-patients
#20
Anne-Li Lind, Di Wu, Eva Freyhult, Constantin Bodolea, Titti Ekegren, Anders Larsson, Mats G Gustafsson, Lenka Katila, Jonas Bergquist, Torsten Gordh, Ulf Landegren, Masood Kamali-Moghaddam
The objective of this study was to develop and apply a novel multiplex panel of solid-phase proximity ligation assays (SP-PLA) requiring only 20 μL of samples, as a tool for discovering protein biomarkers for neurological disease and treatment thereof in cerebrospinal fluid (CSF). We applied the SP-PLA to samples from two sets of patients with poorly understood nervous system pathologies amyotrophic lateral sclerosis (ALS) and neuropathic pain, where patients were treated with spinal cord stimulation (SCS)...
2016: PloS One
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