collection
MENU ▼
Read by QxMD icon Read
search

Deep Brain Stimulation literature

shared collection
169 papers 25 to 100 followers
https://www.readbyqxmd.com/read/27104841/effect-of-low-frequency-deep-brain-stimulation-on-sensory-thresholds-in-parkinson-s-disease
#1
Abigail Belasen, Khizer Rizvi, Lucy E Gee, Philip Yeung, Julia Prusik, Adolfo Ramirez-Zamora, Era Hanspal, Priscilla Paiva, Jennifer Durphy, Charles E Argoff, Julie G Pilitsis
OBJECTIVE Chronic pain is a major distressing symptom of Parkinson's disease (PD) that is often undertreated. Subthalamic nucleus (STN) deep brain stimulation (DBS) delivers high-frequency stimulation (HFS) to patients with PD and has been effective in pain relief in a subset of these patients. However, up to 74% of patients develop new pain concerns while receiving STN DBS. Here the authors explore whether altering the frequency of STN DBS changes pain perception as measured through quantitative sensory testing (QST)...
April 22, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27739021/surgical-treatment-of-parkinson-s-disease
#2
Leo Verhagen Metman, Gian Pal, Konstantin Slavin
Deep brain stimulation is now an established therapy for Parkinson's disease, and DBS continues to be refined. Well-established targets, such as the STN and GPi, have shown clear benefit in reducing motor complications in PD, and other more novel targets, such as PPN are being explored. Furthermore, there have been advances in imaging which allow for improved lead placement and also can reduce patient discomfort. The way electrical current is delivered through the DBS lead is also undergoing a transformation, allowing for more options regarding current shaping, steering, and new stimulation paradigms...
November 2016: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/27784023/deep-brain-stimulation-of-the-caudal-zona-incerta-tremor-control-in-relation-to-the-location-of-stimulation-fields
#3
Anders Fytagoridis, Mattias Åström, Jennifer Samuelsson, Patric Blomstedt
BACKGROUND: The caudal zona incerta (cZi) and posterior subthalamic area (PSA) are an emerging deep brain stimulation (DBS) target for essential tremor (ET). OBJECTIVES: To evaluate the efficacy of tremor control in relation to the anatomical locations of stimulation fields in 50 patients with ET and DBS of the cZi. METHODS: A total of 240 contacts were evaluated separately with monopolar stimulation, and amplitudes were optimized for improvement of tremor and hand function...
October 27, 2016: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/27797157/local-sar-near-deep-brain-stimulation-dbs-electrodes-at-64-and-127-mhz-a-simulation-study-of-the-effect-of-extracranial-loops
#4
Laleh Golestanirad, Leonardo M Angelone, Maria Ida Iacono, Husam Katnani, Lawrence L Wald, Giorgio Bonmassar
PURPOSE: MRI may cause brain tissue around deep brain stimulation (DBS) electrodes to become excessively hot, causing lesions. The presence of extracranial loops in the DBS lead trajectory has been shown to affect the specific absorption rate (SAR) of the radiofrequency energy at the electrode tip, but experimental studies have reported controversial results. The goal of this study was to perform a systematic numerical study to provide a better understanding of the effects of extracranial loops in DBS leads on the local SAR during MRI at 64 and 127 MHz...
October 31, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27798944/deep-brain-stimulation-of-the-anterior-limb-of-the-internal-capsule-may-be-efficacious-for-explosive-aggressive-behaviour
#5
Flavio Giordano, Michele Cavallo, Barbara Spacca, Stefano Pallanti, Francesco Tomaiuolo, Fulvio Pieraccini, Andrea Fagiolini, Manuela Grandoni, Federico Melani, Anna Zicca, Stelvio Sestini, Lorenzo Genitori
BACKGROUND: Intermittent explosive disease (IED) is a psychiatric disorder characterized by intermittent attacks of rage and violence frequently resistant to pharmacological therapy. Deep brain stimulation (DBS) of the posteromedial hypothalamus has been applied with fair results and clinical improvement with some surgical morbidity due to neurovegetative side effects. The anterior limb of the internal capsule/ventral capsule/ventral striatum (VC/VS) has never been used alone as a target for this disease...
November 1, 2016: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/27799482/teaching-neuroimages-noninfectious-cyst-as-an-unusual-complication-of-deep-brain-stimulation
#6
Harsh V Gupta, Mark K Lyons, Shyamal H Mehta
No abstract text is available yet for this article.
November 1, 2016: Neurology
https://www.readbyqxmd.com/read/27800157/the-study-of-brain-functional-connectivity-in-parkinson-s-disease
#7
REVIEW
Lin-Lin Gao, Tao Wu
Parkinson's disease (PD) is a neurodegenerative disorder primarily affecting the aging population. The neurophysiological mechanisms underlying parkinsonian symptoms remain unclear. PD affects extensive neural networks and a more thorough understanding of network disruption will help bridge the gap between known pathological changes and observed clinical presentations in PD. Development of neuroimaging techniques, especially functional magnetic resonance imaging, allows for detection of the functional connectivity of neural networks in patients with PD...
2016: Translational Neurodegeneration
https://www.readbyqxmd.com/read/27807672/nucleus-accumbens-deep-brain-stimulation-for-a-patient-with-self-injurious-behavior-and-autism-spectrum-disorder-functional-and-structural-changes-of-the-brain-report-of-a-case-and-review-of-literature
#8
Hye Ran Park, In Hyang Kim, Hyejin Kang, Dong Soo Lee, Bung-Nyun Kim, Dong Gyu Kim, Sun Ha Paek
The aim of this report was to investigate the clinical outcome of deep brain stimulation (DBS) for autism spectrum disorder (ASD) and the functional and structural changes in the brain after DBS. We present a 14-year-old boy with ASD and self-injurious behavior (SIB) refractory with medical and behavioral therapy. He was treated by bilateral nucleus accumbens (NAc) DBS. Remarkable clinical improvement was observed following NAc DBS. Brain fluorodeoxyglucose-positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) volumetric studies revealed that the metabolism in the prefrontal and the frontal cortex as well as the occipital cortex was markedly decreased in association with the decreased cortical volumes in those areas 2 years after NAc DBS...
November 3, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27812317/trigeminal-cardiac-reflex-and-cerebral-blood-flow-regulation
#9
REVIEW
Dominga Lapi, Rossana Scuri, Antonio Colantuoni
The stimulation of some facial regions is known to trigger the trigemino-cardiac reflex: the main stimulus is represented by the contact of the face with water. This phenomenon called diving reflex induces a set of reactions in the cardiovascular and respiratory systems occurring in all mammals, especially marine (whales, seals). During the immersion of the face in the water, the main responses are aimed at reducing the oxygen consumption of the organism. Accordingly reduction in heart rate, peripheral vasoconstriction, blood pooling in certain organs, especially the heart, and brain and an increase in blood pressure have been reported...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27812714/deep-brain-stimulation-for-treatment-refractory-depression
#10
Puneet Narang, Amber Retzlaff, Kanwarjeet Brar, Steven Lippmann
Depression has a high lifetime prevalence and recurrence rate, with more than one-third of affected patients experiencing treatment-refractory depression. These individuals should benefit from additional treatment options such as deep brain stimulation (DBS), a research-grade intervention. DBS is being investigated for its efficacy in treatment-refractory cases. We reviewed the English-language literature published between the years 2010 and 2015 regarding the utility of DBS for patients with treatment-refractory depression...
November 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27815831/current-perspective-of-stem-cell-therapy-in-neurodegenerative-and-metabolic-diseases
#11
REVIEW
Ajay Kumar, Karthikeyan Narayanan, Ravi Kumar Chaudhary, Sachin Mishra, Sundramurthy Kumar, Kumar Jayaseelan Vinoth, Parasuraman Padmanabhan, Balázs Gulyás
Neurodegenerative diseases have been an unsolved riddle for quite a while; to date, there are no proper and effective curative treatments and only palliative and symptomatic treatments are available to treat these illnesses. The absence of therapeutic treatments for neurodegenerative ailments has huge economic hit and strain on the society. Pharmacotherapies and various surgical procedures like deep brain stimulation are being given to the patient, but they are only effective for the symptoms and not for the diseases...
November 4, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27818350/modulations-on-cortical-oscillations-by-subthalamic-deep-brain-stimulation-in-patients-with-parkinson-disease-a-meg-study
#12
Chun-Yan Cao, Ke Zeng, Dian-You Li, Shi-Kun Zhan, Xiao-Li Li, Bo-Min Sun
OBJECTIVE: The study aimed to explore the modification to cortical oscillations of Parkinson disease (PD) patients by subthalamic nucleus deep brain stimulation (STN DBS). METHODS: With Magnetoencephalogram (MEG) detection, we examined the changes in absolute power spectrum of cortical oscillations in the PD patients with the treatment of STN DBS. RESULTS: The power analysis of PD patients showed a dominant over-synchronization of alpha and beta bands in temporal and occipital areas relative to the healthy control subjects...
November 3, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27820615/the-problem-of-funding-off-label-deep-brain-stimulation-bait-and-switch-tactics-and-the-need-for-policy-reform
#13
P Justin Rossi, James Giordano, Michael S Okun
No abstract text is available yet for this article.
November 7, 2016: JAMA Neurology
https://www.readbyqxmd.com/read/27821134/asphyxia-due-to-laryngeal-spasm-as-a-severe-complication-of-awake-deep-brain-stimulation-for-parkinson-s-disease-a-case-report
#14
Kajetan L von Eckardstein, Friederike Sixel-Döring, Stephan Kazmaier, Claudia Trenkwalder, Jason M Hoover, Veit Rohde
BACKGROUND: In accordance with German neurosurgical and neurological consensus recommendations, lead placements for deep brain stimulation (DBS) in patients with Parkinson's disease (PD) are usually performed with the patient awake and in "medication off" state. This allows for optimal lead position adjustment according to the clinical response to intraoperative test stimulation. However, exacerbation of Parkinsonian symptoms after withdrawal of dopaminergic medication may endanger the patient by inducing severe "off" state motor phenomena...
November 8, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27825979/functional-circuit-mapping-of-striatal-output-nuclei-using-simultaneous-deep-brain-stimulation-and-fmri
#15
Nathalie Van Den Berge, Daniel L Albaugh, Andrew Salzwedel, Christian Vanhove, Roel Van Holen, Wei Gao, Garret D Stuber, Yen-Yu Ian Shih
The substantia nigra pars reticulata (SNr) and external globus pallidus (GPe) constitute the two major output targets of the rodent striatum. Both the SNr and GPe converge upon thalamic relay nuclei (directly or indirectly, respectively), and are traditionally modeled as functionally antagonistic relay inputs. However, recent anatomical and functional studies have identified unanticipated circuit connectivity in both the SNr and GPe, demonstrating their potential as far more than relay nuclei. In the present study, we employed simultaneous deep brain stimulation and functional magnetic resonance imaging (DBS-fMRI) with cerebral blood volume (CBV) measurements to functionally and unbiasedly map the circuit- and network level connectivity of the SNr and GPe...
November 5, 2016: NeuroImage
https://www.readbyqxmd.com/read/27826085/short-term-adverse-outcomes-following-deep-brain-stimulation-treatment-in-parkinson-s-disease-patients
#16
Kejia Hu, Ziev B Moses, Matthew Hutter, Ziv Williams
BACKGROUND: Despite ongoing progress in our understanding of long-term outcomes following neuromodulation procedures, acute adverse outcomes shortly after deep brain stimulation (DBS) treatment have remained remarkably limited. OBJECTIVE: To identify risk factors associated with acute 30-day outcomes following DBS treatment in Parkinson's disease (PD) patients. METHODS: We evaluated patients who underwent DBS treatment for PD from 2005 to 2014 through the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database...
November 5, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27826233/the-parkinsonian-subthalamic-network-measures-of-power-linear-and-non-linear-synchronization-and-their-relationship-to-l-dopa-treatment-and-off-state-motor-severity
#17
Timothy West, Simon Farmer, Luc Berthouze, Ashwani Jha, Martijn Beudel, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Peter Brown, Vladimir Litvak
In this paper we investigated the dopaminergic modulation of neuronal interactions occurring in the subthalamic nucleus (STN) during Parkinson's disease (PD). We utilized linear measures of local and long range synchrony such as power and coherence, as well as Detrended Fluctuation Analysis for Phase Synchrony (DFA-PS)- a recently developed non-linear method that computes the extent of long tailed autocorrelations present in the phase interactions between two coupled signals. Through analysis of local field potentials (LFPs) taken from the STN we seek to determine changes in the neurodynamics that may underpin the pathophysiology of PD in a group of 12 patients who had undergone surgery for deep brain stimulation...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27843765/t2-relaxometry-predicts-outcome-of-dbs-in-idiopathic-parkinson-s-disease
#18
Tarja Lönnfors-Weitzel, Thilo Weitzel, Johannes Slotboom, Claus Kiefer, Claudio Pollo, Michael Schüpbach, Markus Oertel, Alain Kaelin, Roland Wiest
INTRODUCTION: Deep brain stimulation (DBS) nowadays is a well-established treatment of motor symptoms in Parkinson's disease. The subthalamic nucleus (STN) is a common target for DBS, because motor improvements have been shown to be superior to best medical therapy, if DBS electrodes have been appropriately positioned. DBS target identification can be assisted by MRI beyond structural imaging by spatially resolved measurement of T2-relaxation times (T2r). AIM: We pose the question, whether T2r of the STN is linked to the severity of the disease and whether outcome of DBS may be correlated to an asymmetric manifestation of the disease...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27462207/feasibility-of-diffusion-tractography-for-the-reconstruction-of-intra-thalamic-and-cerebello-thalamic-targets-for-functional-neurosurgery-a-multi-vendor-pilot-study-in-four-subjects
#19
András Jakab, Beat Werner, Marco Piccirelli, Kázmér Kovács, Ernst Martin, John S Thornton, Tarek Yousry, Gabor Szekely, Ruth O'Gorman Tuura
Functional stereotactic neurosurgery by means of deep brain stimulation or ablation provides an effective treatment for movement disorders, but the outcome of surgical interventions depends on the accuracy by which the target structures are reached. The purpose of this pilot study was to evaluate the feasibility of diffusion tensor imaging (DTI) based probabilistic tractography of deep brain structures that are commonly used for pre- and perioperative targeting for functional neurosurgery. Three targets were reconstructed based on their significance as intervention sites or as a no-go area to avoid adverse side effects: the connections propagating from the thalamus to (1) primary and supplementary motor areas, (2) to somatosensory areas and the cerebello-thalamic tract (CTT)...
2016: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/27465487/modeling-laterality-of-the-globus-pallidus-internus-in-patients-with-parkinson-s-disease
#20
Justin Sharim, Daniel Yazdi, Amy Baohan, Eric Behnke, Nader Pouratian
OBJECTIVE: Neurosurgical interventions such as deep brain stimulation surgery of the globus pallidus internus (GPi) play an important role in the treatment of medically refractory Parkinson's disease (PD), and require high targeting accuracy. Variability in the laterality of the GPi across patients with PD has not been well characterized. The aim of this report is to identify factors that may contribute to differences in position of the motor region of GPi. MATERIALS AND METHODS: The charts and operative reports of 101 PD patients following deep brain stimulation surgery (70 males, aged 11-78 years) representing 201 GPi were retrospectively reviewed...
July 28, 2016: Neuromodulation: Journal of the International Neuromodulation Society
label_collection
label_collection
5503
1
2
2016-08-05 06:59:48
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"