Catherine G Coughlin, Stephanie C Cohen, Jilian M Mulqueen, Eduardo Ferracioli-Oda, Zachary D Stuckelman, Michael H Bloch
OBJECTIVE: Anxiety is a commonly reported side-effect of psychostimulant treatment. Our goal was to quantify the risk of anxiety as a side effect of psychostimulant treatment for attention-deficit/hyperactivity disorder (ADHD). METHODS: We conducted a PubMed search to identify all double-blind, randomized, placebo-controlled trials examining the efficacy of psychostimulant medications in the treatment of children with ADHD. We used a fixed-effects meta-analysis to examine the risk ratio of anxiety reported as a side effect in children treated with psychostimulants compared with those treated with placebo...
October 2015: Journal of Child and Adolescent Psychopharmacology