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Polymyalgia rheumatica

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6 papers 0 to 25 followers
https://www.readbyqxmd.com/read/26929219/efficacy-of-first-line-tocilizumab-therapy-in-early-polymyalgia-rheumatica-a-prospective-longitudinal-study
#1
Valérie Devauchelle-Pensec, Jean Marie Berthelot, Divi Cornec, Yves Renaudineau, Thierry Marhadour, Sandrine Jousse-Joulin, Solène Querellou, Florent Garrigues, Michel De Bandt, Maelenn Gouillou, Alain Saraux
BACKGROUND: Glucocorticoids are the cornerstone treatment of polymyalgia rheumatica (PMR) but induce adverse events. OBJECTIVES: To evaluate the efficacy and safety of first-line tocilizumab in PMR. METHODS: In a prospective open-label study (ClinicalTrials.gov: NCT01713842), 20 glucocorticoid-free patients fulfilling Chuang's PMR criteria, with symptom onset within the last 12 months and a PMR activity score (PMR-AS) >10, each received three tocilizumab infusions at 4-week intervals, without glucocorticoids, followed by oral prednisone from weeks 12 to 24 (0...
August 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/26683194/2015-eular-acr-recommendations-for-polymyalgia-rheumatica-the-message-and-next-steps
#2
EDITORIAL
Lauren Steel, Marwan Bukhari, Bhaskar Dasgupta
No abstract text is available yet for this article.
June 2016: Rheumatology
https://www.readbyqxmd.com/read/26352874/2015-recommendations-for-the-management-of-polymyalgia-rheumatica-a-european-league-against-rheumatism-american-college-of-rheumatology-collaborative-initiative
#3
Christian Dejaco, Yogesh P Singh, Pablo Perel, Andrew Hutchings, Dario Camellino, Sarah Mackie, Andy Abril, Artur Bachta, Peter Balint, Kevin Barraclough, Lina Bianconi, Frank Buttgereit, Steven Carsons, Daniel Ching, Maria Cid, Marco Cimmino, Andreas Diamantopoulos, William Docken, Christina Duftner, Billy Fashanu, Kate Gilbert, Pamela Hildreth, Jane Hollywood, David Jayne, Manuella Lima, Ajesh Maharaj, Christian Mallen, Victor Martinez-Taboada, Mehrdad Maz, Steven Merry, Jean Miller, Shunsuke Mori, Lorna Neill, Elisabeth Nordborg, Jennifer Nott, Hannah Padbury, Colin Pease, Carlo Salvarani, Michael Schirmer, Wolfgang Schmidt, Robert Spiera, David Tronnier, Alexandre Wagner, Madeline Whitlock, Eric L Matteson, Bhaskar Dasgupta
Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use...
October 2015: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/26376658/whole-body-mri-of-patients-with-polymyalgia-rheumatica-identifies-a-distinct-subset-with-complete-patient-reported-response-to-glucocorticoids
#4
Sarah Louise Mackie, Colin Thomas Pease, Eiji Fukuba, Emma Harris, Paul Emery, Richard Hodgson, Jane Freeston, Dennis McGonagle
OBJECTIVES: To determine whether whole-body MRI defines clinically relevant subgroups within polymyalgia rheumatica (PMR) including glucocorticoid responsiveness. METHODS: 22 patients with PMR and 16 with rheumatoid arthritis (RA), untreated and diagnosed by consultant rheumatologists, underwent whole-body, multiple-joint MRI, scored by two experts. Patients with PMR reported whether they felt 'back to normal' on glucocorticoid therapy and were followed for a median of 2 years...
December 2015: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/26359489/current-evidence-for-therapeutic-interventions-and-prognostic-factors-in-polymyalgia-rheumatica-a-systematic-literature-review-informing-the-2015-european-league-against-rheumatism-american-college-of-rheumatology-recommendations-for-the-management-of-polymyalgia
#5
REVIEW
Christian Dejaco, Yogesh P Singh, Pablo Perel, Andrew Hutchings, Dario Camellino, Sarah Mackie, Eric L Matteson, Bhaskar Dasgupta
To summarise evidence on therapeutic interventions and prognostic factors in polymyalgia rheumatica (PMR). A systematic literature review was conducted using Ovid Medline, Embase, PubMed, CINAHL, Web of Science and the Cochrane Library (1970 through April 2014). Quality of evidence (QoE) of identified studies was appraised by Grading of Recommendations Assessment, Development and Evaluation (GRADE) (interventions) and the Quality In Prognosis Studies (QUIPS) methodologies (prognostic factors). Out of 10 931 titles identified, 52 articles were finally selected...
October 2015: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/26359488/2015-recommendations-for-the-management-of-polymyalgia-rheumatica-a-european-league-against-rheumatism-american-college-of-rheumatology-collaborative-initiative
#6
Christian Dejaco, Yogesh P Singh, Pablo Perel, Andrew Hutchings, Dario Camellino, Sarah Mackie, Andy Abril, Artur Bachta, Peter Balint, Kevin Barraclough, Lina Bianconi, Frank Buttgereit, Steven Carsons, Daniel Ching, Maria Cid, Marco Cimmino, Andreas Diamantopoulos, William Docken, Christina Duftner, Billy Fashanu, Kate Gilbert, Pamela Hildreth, Jane Hollywood, David Jayne, Manuella Lima, Ajesh Maharaj, Christian Mallen, Victor Martinez-Taboada, Mehrdad Maz, Steven Merry, Jean Miller, Shunsuke Mori, Lorna Neill, Elisabeth Nordborg, Jennifer Nott, Hannah Padbury, Colin Pease, Carlo Salvarani, Michael Schirmer, Wolfgang Schmidt, Robert Spiera, David Tronnier, Alexandre Wagner, Madeline Whitlock, Eric L Matteson, Bhaskar Dasgupta
Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use...
October 2015: Annals of the Rheumatic Diseases
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