collection
https://read.qxmd.com/read/27070064/understanding-bacterial-isolates-in-blood-culture-and-approaches-used-to-define-bacteria-as-contaminants-a-literature-review
#1
REVIEW
Belal Hossain, Mohammad Shahidul Islam, Atiqur Rahman, Mahfuza Marzan, Iftekhar Rafiqullah, Nicholas E Connor, Mohammad Hasanuzzaman, Maksuda Islam, Davidson H Hamer, Patricia L Hibberd, Samir K Saha
BACKGROUND: Interpretation of blood culture isolates is challenging due to a lack of standard methodologies for identifying contaminants. This problem becomes more complex when the specimens are from sick young infants, as a wide range of bacteria can cause illness among this group. METHODS: We used 43 key words to find articles published between 1970 and 2011 on blood culture isolates and possible contaminants in the PubMed database. Experts were also consulted to obtain other relevant articles...
May 2016: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/27085369/association-of-fluid-resuscitation-initiation-within-30-minutes-of-severe-sepsis-and-septic-shock-recognition-with-reduced-mortality-and-length-of-stay
#2
JOURNAL ARTICLE
Daniel Leisman, Benjamin Wie, Martin Doerfler, Andrea Bianculli, Mary Frances Ward, Meredith Akerman, John K D'Angelo, Jason A Zemmel D'Amore
STUDY OBJECTIVE: We evaluate the association of intravenous fluid resuscitation initiation within 30 minutes of severe sepsis or septic shock identification in the emergency department (ED) with inhospital mortality and hospital length of stay. We also compare intravenous fluid resuscitation initiated at various times from severe sepsis or septic shock identification's association with the same outcomes. METHODS: This was a review of a prospective, observational cohort of all ED severe sepsis or septic shock patients during 13 months, captured in a performance improvement database at a single, urban, tertiary care facility (90,000 ED visits/year)...
September 2016: Annals of Emergency Medicine
https://read.qxmd.com/read/27130800/utility-of-central-venous-pressure-as-a-predictor-of-fluid-responsiveness
#3
EDITORIAL
Michael Gottlieb, Benton Hunter
No abstract text is available yet for this article.
July 2016: Annals of Emergency Medicine
https://read.qxmd.com/read/26903338/the-third-international-consensus-definitions-for-sepsis-and-septic-shock-sepsis-3
#4
JOURNAL ARTICLE
Mervyn Singer, Clifford S Deutschman, Christopher Warren Seymour, Manu Shankar-Hari, Djillali Annane, Michael Bauer, Rinaldo Bellomo, Gordon R Bernard, Jean-Daniel Chiche, Craig M Coopersmith, Richard S Hotchkiss, Mitchell M Levy, John C Marshall, Greg S Martin, Steven M Opal, Gordon D Rubenfeld, Tom van der Poll, Jean-Louis Vincent, Derek C Angus
IMPORTANCE: Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the pathobiology (changes in organ function, morphology, cell biology, biochemistry, immunology, and circulation), management, and epidemiology of sepsis, suggesting the need for reexamination. OBJECTIVE: To evaluate and, as needed, update definitions for sepsis and septic shock. PROCESS: A task force (n = 19) with expertise in sepsis pathobiology, clinical trials, and epidemiology was convened by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine...
February 23, 2016: JAMA
https://read.qxmd.com/read/27058468/early-liberal-fluids-for-sepsis-patients-are-harmful
#5
JOURNAL ARTICLE
Kelly Genga, James A Russell
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://read.qxmd.com/read/26378980/lactic-acidosis-in-sepsis-it-s-not-all-anaerobic-implications-for-diagnosis-and-management
#6
REVIEW
Bandarn Suetrong, Keith R Walley
Increased blood lactate concentration (hyperlactatemia) and lactic acidosis (hyperlactatemia and serum pH < 7.35) are common in patients with severe sepsis or septic shock and are associated with significant morbidity and mortality. In some patients, most of the lactate that is produced in shock states is due to inadequate oxygen delivery resulting in tissue hypoxia and causing anaerobic glycolysis. However, lactate formation during sepsis is not entirely related to tissue hypoxia or reversible by increasing oxygen delivery...
January 2016: Chest
https://read.qxmd.com/read/25959848/improved-sepsis-bundles-in-the-treatment-of-septic-shock-a-prospective-clinical-study
#7
RANDOMIZED CONTROLLED TRIAL
Nian-Fang Lu, Rui-Qiang Zheng, Hua Lin, Jun Shao, Jiang-Quan Yu, De-Gang Yang
BACKGROUND: Sepsis bundles can decrease mortality in patients with severe sepsis or septic shock. However, current methods of measuring pressure, such as central venous pressure, are inadequate. This study investigated the effect of improved sepsis bundles informed by pulse-indicated continuous cardiac output. METHODS: We compared the outcome of treatment with sepsis bundles informed by either conventional pressure measurements or pulse-indicated continuous cardiac output...
August 2015: American Journal of Emergency Medicine
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