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Obstetrícia

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5 papers 0 to 25 followers
https://www.readbyqxmd.com/read/27661655/practice-bulletin-no-172-premature-rupture-of-membranes
#1
(no author information available yet)
Preterm delivery occurs in approximately 12% of all births in the United States and is a major factor that contributes to perinatal morbidity and mortality (1, 2). Preterm premature rupture of membranes (PROM) complicates approximately 3% of all pregnancies in the United States (3). The optimal approach to clinical assessment and treatment of women with term and preterm PROM remains controversial. Management hinges on knowledge of gestational age and evaluation of the relative risks of delivery versus the risks of expectant management (eg, infection, abruptio placentae, and umbilical cord accident)...
October 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26114726/committee-opinion-no-640-cell-free-dna-screening-for-fetal-aneuploidy
#2
(no author information available yet)
Noninvasive prenatal screening that uses cell-free DNA from the plasma of pregnant women offers tremendous potential as a screening method for fetal aneuploidy. A number of laboratories have validated different techniques for the use of cell-free DNA as a screening test for fetal aneuploidy. All tests have a high sensitivity and specificity for trisomy 18 and trisomy 21, regardless of which molecular technique is used. Women whose results are not reported, indeterminate, or uninterpretable (a "no call" test result) from cell-free DNA screening should receive further genetic counseling and be offered comprehensive ultrasound evaluation and diagnostic testing because of an increased risk of aneuploidy...
June 29, 2015: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/26113227/the-importance-of-the-cerebroplacental-ratio-in-the-evaluation-of-fetal-well-being-in-sga-and-aga-fetuses
#3
REVIEW
Greggory R DeVore
The cerebroplacental ratio (CPR) is emerging as an important predictor of adverse pregnancy outcome, and this has implications for the assessment of fetal well-being in fetuses diagnosed as small for gestational age (SGA) and those appropriate for gestational age close to term. Interest in this assessment tool has been rekindled because of recent reports associating an abnormal ratio with adverse perinatal events and associated postnatal neurological outcome. Fetuses with an abnormal CPR that are appropriate for gestational age or have late-onset SGA (>34 weeks of gestation) have a higher incidence of fetal distress in labor requiring emergency cesarean delivery, a lower cord pH, and an increased admission rate to the newborn intensive care unit when compared with fetuses with a normal CPR...
July 2015: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/24832366/oral-antihypertensive-therapy-for-severe-hypertension-in-pregnancy-and-postpartum-a-systematic-review
#4
REVIEW
T Firoz, L A Magee, K MacDonell, B A Payne, R Gordon, M Vidler, P von Dadelszen
BACKGROUND: Pregnant and postpartum women with severe hypertension are at increased risk of stroke and require blood pressure (BP) reduction. Parenteral antihypertensives have been most commonly studied, but oral agents would be ideal for use in busy and resource-constrained settings. OBJECTIVES: To review systematically, the effectiveness of oral antihypertensive agents for treatment of severe pregnancy/postpartum hypertension. SEARCH STRATEGY: A systematic search of MEDLINE, EMBASE and the Cochrane Library was performed...
September 2014: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/22284156/vaginal-progesterone-in-women-with-an-asymptomatic-sonographic-short-cervix-in-the-midtrimester-decreases-preterm-delivery-and-neonatal-morbidity-a-systematic-review-and-metaanalysis-of-individual-patient-data
#5
REVIEW
Roberto Romero, Kypros Nicolaides, Agustin Conde-Agudelo, Ann Tabor, John M O'Brien, Elcin Cetingoz, Eduardo Da Fonseca, George W Creasy, Katharina Klein, Line Rode, Priya Soma-Pillay, Shalini Fusey, Cetin Cam, Zarko Alfirevic, Sonia S Hassan
OBJECTIVE: To determine whether the use of vaginal progesterone in asymptomatic women with a sonographic short cervix (≤ 25 mm) in the midtrimester reduces the risk of preterm birth and improves neonatal morbidity and mortality. STUDY DESIGN: Individual patient data metaanalysis of randomized controlled trials. RESULTS: Five trials of high quality were included with a total of 775 women and 827 infants. Treatment with vaginal progesterone was associated with a significant reduction in the rate of preterm birth <33 weeks (relative risk [RR], 0...
February 2012: American Journal of Obstetrics and Gynecology
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