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lung cancer update

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3 papers 25 to 100 followers
By Jason Mann No BS pulmonary critical care fellow
Francesco Fraioli, Irfan Kayani, Laura-Jane Smith, Jamshed B Bomanji, Arrigo Capitanio, Mary Falzon, Bernadette Carroll, Neal Navani, James Brown, Ricky M Thakrar, Philip Jeremy George, Ashley M Groves, Sam M Janes
No abstract text is available yet for this article.
March 1, 2016: American Journal of Respiratory and Critical Care Medicine
Nathan A Pennell
Although immunotherapy has been used for decades in immunogenic tumor types, such as melanoma and renal cell carcinoma, historically immunotherapeutic approaches in other tumor types, including non-small cell lung cancer (NSCLC), have met with failure. Nonetheless, evidence exists supporting the role of the immune system in tumor suppression, even in tumor types believed to be non-immunogenic. In NSCLC, immune checkpoint molecules have recently proven to be successful targets, with nivolumab, the first immune checkpoint inhibitor indicated for NSCLC, approved by the US Food and Drug Administration in March 2015...
October 2015: Seminars in Oncology
Avrum Spira, Balazs Halmos, Charles A Powell
In the past 2 years, lung cancer research and clinical care have advanced significantly. Advancements in the field have improved outcomes and promise to lead to further reductions in deaths from lung cancer, the leading cause of cancer death worldwide. These advances include identification of new molecular targets for personalized targeted therapy, validation of molecular signatures of lung cancer risk in smokers, progress in lung tumor immunotherapy, and implementation of population-based lung cancer screening with chest computed tomography in the United States...
August 1, 2015: American Journal of Respiratory and Critical Care Medicine
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