Christopher J Ryerson, Eric Vittinghoff, Brett Ley, Joyce S Lee, Joshua J Mooney, Kirk D Jones, Brett M Elicker, Paul J Wolters, Laura L Koth, Talmadge E King, Harold R Collard
BACKGROUND: Risk prediction is challenging in chronic interstitial lung disease (ILD) because of heterogeneity in disease-specific and patient-specific variables. Our objective was to determine whether mortality is accurately predicted in patients with chronic ILD using the GAP model, a clinical prediction model based on sex, age, and lung physiology, that was previously validated in patients with idiopathic pulmonary fibrosis. METHODS: Patients with idiopathic pulmonary fibrosis (n=307), chronic hypersensitivity pneumonitis (n=206), connective tissue disease-associated ILD (n=281), idiopathic nonspecific interstitial pneumonia (n=45), or unclassifiable ILD (n=173) were selected from an ongoing database (N=1,012)...
April 2014: Chest