S Rigucci, T R Marques, M Di Forti, H Taylor, F Dell'Acqua, V Mondelli, S Bonaccorso, A Simmons, A S David, P Girardi, C M Pariante, R M Murray, P Dazzan
BACKGROUND: The use of cannabis with higher Δ9-tetrahydrocannabinol content has been associated with greater risk, and earlier onset, of psychosis. However, the effect of cannabis potency on brain morphology has never been explored. Here, we investigated whether cannabis potency and pattern of use are associated with changes in corpus callosum (CC) microstructural organization, in patients with first-episode psychosis (FEP) and individuals without psychosis, cannabis users and non-users...
March 2016: Psychological Medicine