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By Alfredo Levy Medico ginecólogo obstetra especialista en infertilidad y endometriosis cirugia mínima invasiva!
Mei Yang, Chunfan Jiang, Hua Chen, Yan Nian, Zhimiao Bai, Chunfang Ha
BACKGROUND: Endometriosis, which shares certain characteristics with cancers, may cause abnormal expression of proteins involved in cell migration. Endometrial epithelial cells (EECs) are believed to play an important role in endometriotic migration. The aim of this study was to investigate the relationship between the expression of osteopontin (OPN) and matrix metalloproteinase-9 (MMP-9) in endometriotic migration. METHODS: We performed primary culture of EECs and investigated the expression of OPN and MMP-9 in EECs regulated by 17beta-estradiol (E2)...
August 20, 2015: Reproductive Biology and Endocrinology: RB&E
Naohisa Nakagawa, Hiromi Koda, Noriko Nitta, Yukie Nakahara, Jiro Uno, Toru Hashimoto, Takashi Nakahori, Masaaki Hasegawa, Mikio Kataoka
Previous reports have shown that some ovarian endometrioid adenocarcinomas and ovarian clear cell adenocarcinomas derive from ovarian endometriosis (OE), and that endocervical-like mucinous borderline ovarian tumors are associated with OE. We examined the relationship between the staging and histological subtypes of OE or epithelial ovarian tumors (EOT) and the serum levels of carbohydrate antigen 19-9 (CA19-9) and carbohydrate antigen 125 (CA125) to evaluate the potential of these markers for preoperative diagnosis...
2015: Acta Medica Okayama
Fuminori Taniguchi, Akiko Enatsu, Ikuko Ota, Toshiko Toda, Kazuya Arata, Tasuku Harada
OBJECTIVES: Low dose oral contraceptive pills (OCPs) that contain synthetic estrogen and progestin are often used to relieve chronic pelvic pain associated with endometriosis. We sought to evaluate the efficacy of drospirenone/ethinylestradiol (DRSP/EE) with low-dose estrogen in treating endometrioma. STUDY DESIGN: A prospective clinical study in six hospitals and one clinic in Japan was conducted. Forty-nine 23- to 45-year-old patients who suffered from endometriosis-associated dysmenorrhea were included in the study...
August 2015: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Monica Holicov Luţuc, D Nemescu, Alina Onofriescu, Mihaela Târnovanu, Mihaela Moscalu, M Onofriescu
AIM: The study deals with the preoperative ultrasound diagnosis of ovarian endometriosis, postoperative ultrasound reassessment, laparoscopic surgical resolution of ovarian endometriosis, estimation of recurrence risk 12 months after surgery by ultrasound, reappearance of clinical symptoms (such as pain) or second-look laparoscopy, and pregnancy rate 2 years after surgery. MATERIAL AND METHODS: 140 patients with en- dometriosis and infertility admitted to the Iasi "Cuza-Vodă" Clinical Hospital of Obstetrics and Gynecology between the years 2009-2011 were included in the study...
January 2015: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Y-Q Ruan, W-G Liang, S-H Huang
OBJECTIVE: To analyze the clinical effect of laparoscopy on patients with endometriosis and a high expression of CA125. PATIENTS AND METHODS: One hundred cases of endometriosis treated in our hospital from May 2012 to August 2014 were selected as research subjects, after approval from the hospital and the informed consent of patients. The subjects were randomly divided into a control group and a study group with 50 cases in each group. The control group underwent the traditional surgery, while the research group underwent laparoscopy...
April 2015: European Review for Medical and Pharmacological Sciences
Uche Menakaya, Chuan Lu, Fernando Infante, Alan Lam, George Condous
OBJECTIVES: To determine the correlation between historical variables at presentation with the phenotype and location of biopsy proven endometriosis at laparoscopy. METHODS: Prospective observational study. Consecutive women had laparoscopic surgery following clinical suspicion of endometriosis. Standardised history and clinical examination were taken, and the presenting complaints were evaluated within four subsets of women: (i) primary laparoscopy for endometriosis (ii) previous laparoscopically confirmed endometriosis (iii) biopsy positive for endometriosis and (iv) all biopsies negative for endometriosis...
October 2014: Australian & New Zealand Journal of Obstetrics & Gynaecology
Brittaney M Wilson-Harris, Benjamin Nutter, Tommaso Falcone
STUDY OBJECTIVE: To describe the long-term fertility outcomes in young patients with endometriosis-associated pelvic pain treated with laparoscopic surgery. DESIGN: Retrospective case series (Canadian Task Force classification II-2). SETTING: Tertiary care hospital. PATIENTS: Women aged 18 to 25 years who underwent laparoscopic surgery between 2000 and 2005 at the Cleveland Clinic Foundation solely to treat endometriosis-associated pelvic pain...
November 2014: Journal of Minimally Invasive Gynecology
Kinza Younas, Franz Majoko, Katherine Sheard, Christopher Edwards, Adnan Bunkheila
Infertility affects 1 in 7 couples in the UK. Tubal patency tests are an important part of infertility investigations. We conducted this observational study to determine the interval between a laparoscopy and dye test and spontaneous conception in women with unexplained infertility and minimal to mild endometriosis and pelvic adhesions treated during the procedure. The clinical records of 432 women coded as having had a laparoscopy and dye test or laparoscopy and tubal patency test between April 2007 and March 2010 were retrieved from a computerised theatre database...
March 2014: Human Fertility: Journal of the British Fertility Society
G A J Dunselman, N Vermeulen, C Becker, C Calhaz-Jorge, T D'Hooghe, B De Bie, O Heikinheimo, A W Horne, L Kiesel, A Nap, A Prentice, E Saridogan, D Soriano, W Nelen
STUDY QUESTION: What is the optimal management of women with endometriosis based on the best available evidence in the literature? SUMMARY ANSWER: Using the structured methodology of the Manual for ESHRE Guideline Development, 83 recommendations were formulated that answered the 22 key questions on optimal management of women with endometriosis. WHAT IS KNOWN ALREADY: The European Society of Human Reproduction and Embryology (ESHRE) guideline for the diagnosis and treatment of endometriosis (2005) has been a reference point for best clinical care in endometriosis for years, but this guideline was in need of updating...
March 2014: Human Reproduction
Kelechi E Nnoaham, Lone Hummelshoj, Premila Webster, Thomas d'Hooghe, Fiorenzo de Cicco Nardone, Carlo de Cicco Nardone, Crispin Jenkinson, Stephen H Kennedy, Krina T Zondervan
OBJECTIVE: To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity. DESIGN: Multicenter cross-sectional study with prospective recruitment. SETTING: Sixteen clinical centers in ten countries. PATIENT(S): A total of 1,418 premenopausal women, aged 18-45 years, without a previous surgical diagnosis of endometriosis, having laparoscopy to investigate symptoms or to be sterilized...
August 2011: Fertility and Sterility
G David Adamson
Studies on the respective roles of laparoscopic surgery and IVF in infertile patients with endometriosis and endometriomas are difficult to perform. Appropriate patient management is complex and requires a sophisticated understanding of individualized evidence-based decision making, surgical judgment and technical skills for laparoscopy, and thoughtful utilization of IVF technologies.
December 2005: Fertility and Sterility
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