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31 papers 25 to 100 followers
https://www.readbyqxmd.com/read/27242383/antibiotic-associated-encephalopathy
#1
(no author information available yet)
No abstract text is available yet for this article.
May 31, 2016: Neurology
https://www.readbyqxmd.com/read/26143662/predictors-of-surgical-site-infection-after-hospital-discharge-in-patients-undergoing-major-vascular-surgery
#2
COMPARATIVE STUDY
Jason T Wiseman, Sara Fernandes-Taylor, Maggie L Barnes, R Scott Saunders, Sandeep Saha, Jeffrey Havlena, Paul J Rathouz, K Craig Kent
OBJECTIVE: Surgical site infection (SSI) is one of the most common postoperative complications after vascular reconstruction, producing significant morbidity and hospital readmission. In contrast to SSI that develops while patients are still hospitalized, little is known about the cohort of patients who develop SSI after discharge. In this study, we explore the factors that lead to postdischarge SSI, investigate the differences between risk factors for in-hospital vs postdischarge SSI, and develop a scoring system to identify patients who might benefit from postdischarge monitoring of their wounds...
October 2015: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/26138226/optimizing-the-clinical-pharmacology-of-tuberculosis-medications
#3
REVIEW
E F Egelund, A Alsultan, C A Peloquin
Tuberculosis (TB) treatment has changed little in the past 40 years. The current standard therapy requires four drugs for 2 months followed by two drugs for 4 months. This "short-course" regimen is not based on optimized pharmacokinetic and pharmacodynamic properties, but empiric evidence. A review of existing data suggests that pharmacokinetic variability with isoniazid and rifampin is greater than previously thought, and that efficacy is not as good as traditionally reported. Adding new drugs to the current regimen will be costly and time-consuming...
October 2015: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/26016486/staphylococcus-aureus-infections-epidemiology-pathophysiology-clinical-manifestations-and-management
#4
REVIEW
Steven Y C Tong, Joshua S Davis, Emily Eichenberger, Thomas L Holland, Vance G Fowler
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical infections. It is a leading cause of bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device-related infections. This review comprehensively covers the epidemiology, pathophysiology, clinical manifestations, and management of each of these clinical entities. The past 2 decades have witnessed two clear shifts in the epidemiology of S. aureus infections: first, a growing number of health care-associated infections, particularly seen in infective endocarditis and prosthetic device infections, and second, an epidemic of community-associated skin and soft tissue infections driven by strains with certain virulence factors and resistance to β-lactam antibiotics...
July 2015: Clinical Microbiology Reviews
https://www.readbyqxmd.com/read/25992751/antibiotics-for-abdominal-sepsis
#5
EDITORIAL
Richard P Wenzel, Michael B Edmond
New England Journal of Medicine, Volume 372, Issue 21, Page 2062-2063, May 2015.
May 21, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/25992748/pelvic-inflammatory-disease
#6
REVIEW
Robert C Brunham, Sami L Gottlieb, Jorma Paavonen
New England Journal of Medicine, Volume 372, Issue 21, Page 2039-2048, May 2015.
May 21, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/25899165/infectious-mononucleosis
#7
REVIEW
Paul Lennon, Michael Crotty, John E Fenton
No abstract text is available yet for this article.
April 21, 2015: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/25875259/clostridium-difficile-infection
#8
REVIEW
Daniel A Leffler, J Thomas Lamont
New England Journal of Medicine, Volume 372, Issue 16, Page 1539-1548, April 2015.
April 16, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/25804417/management-of-severe-acute-dental-infections
#9
REVIEW
Douglas P Robertson, William Keys, Riina Rautemaa-Richardson, Ronnie Burns, Andrew J Smith
No abstract text is available yet for this article.
2015: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/25785967/clindamycin-versus-trimethoprim-sulfamethoxazole-for-uncomplicated-skin-infections
#10
RANDOMIZED CONTROLLED TRIAL
Loren G Miller, Robert S Daum, C Buddy Creech, David Young, Michele D Downing, Samantha J Eells, Stephanie Pettibone, Rebecca J Hoagland, Henry F Chambers
BACKGROUND: Skin and skin-structure infections are common in ambulatory settings. However, the efficacy of various antibiotic regimens in the era of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) is unclear. METHODS: We enrolled outpatients with uncomplicated skin infections who had cellulitis, abscesses larger than 5 cm in diameter (smaller for younger children), or both. Patients were enrolled at four study sites. All abscesses underwent incision and drainage...
March 19, 2015: New England Journal of Medicine
https://www.readbyqxmd.com/read/25589091/the-prevention-and-management-of-rabies
#11
REVIEW
Natasha S Crowcroft, Nisha Thampi
No abstract text is available yet for this article.
2015: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/25481111/does-the-choice-of-antibiotic-affect-outcome-in-strep-throat
#12
COMMENT
Cynthia Santos, Stephen Alerhand, Alex Koyfman
There is insufficient evidence to show clinically meaningful differences between antibiotics for group A beta hemolytic streptococci tonsillopharyngitis. Penicillin or amoxicillin is recommended as first choice, given the absence of resistance and low cost.
May 2015: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/25199614/do-oral-antibiotics-after-incision-and-drainage-of-simple-abscesses-improve-cure-rates
#13
REVIEW
Na Rae Ju, Alex Koyfman
No abstract text is available yet for this article.
January 2015: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/24959688/deaths-attributable-to-carbapenem-resistant-enterobacteriaceae-infections
#14
Matthew E Falagas, Giannoula S Tansarli, Drosos E Karageorgopoulos, Konstantinos Z Vardakas
We evaluated the number of deaths attributable to carbapenem-resistant Enterobacteriaceae by using studies from around the world published before April 9, 2012. Attributable death was defined as the difference in all-cause deaths between patients with carbapenem-resistant infections and those with carbapenem-susceptible infections. Online databases were searched, and data were qualitatively synthesized and pooled in a metaanalysis. Nine studies met inclusion criteria: 6 retrospective case-control studies, 2 retrospective cohort studies, and 1 prospective cohort study...
July 2014: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/24877721/resistance-of-escherichia-coli-urinary-isolates-in-ed-treated-patients-from-a-community-hospital
#15
Virginia H Fleming, Bryan P White, Robin Southwood
PURPOSE: The purpose of this study is to provide resistance data for Escherichia coli isolates causing urinary tract infections in emergency department (ED) patients not requiring admission and explore if differences between this subpopulation and the hospital antibiogram exist. Differences between community-acquired urinary tract infection (CA-UTI) and health care-associated (HA-UTI) subgroups were also investigated. METHODS: Patients with a positive urine culture treated and discharged from the ED of a 200-bed community hospital were reviewed...
August 2014: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/24866216/neglected-parasitic-infections-what-every-family-physician-needs-to-know
#16
REVIEW
Dana Woodhall, Jeffrey L Jones, Paul T Cantey, Patricia P Wilkins, Susan P Montgomery
Neglected parasitic infections, including Chagas disease, toxocariasis, cysticercosis, and toxoplasmosis, affect millions of persons in the United States. Relatively few resources have been devoted to surveillance, prevention, and treatment of these diseases. Chagas disease primarily affects Latin American immigrants and can cause heart failure and death if not treated. Immediate antiparasitic treatment is indicated for most patients with acute Chagas disease. Treatment is recommended for patients younger than 18 years who have chronic Chagas disease and is generally recommended for adults younger than 50 years who do not have advanced cardiomyopathy; treatment decisions for other patients should be made on an individual basis...
May 15, 2014: American Family Physician
https://www.readbyqxmd.com/read/24816209/oseltamivir-dosing-in-critically-ill-patients-with-severe-influenza
#17
REVIEW
Alexander H Flannery, Melissa L Thompson Bastin
OBJECTIVE: To evaluate the literature for published reports regarding the efficacy of standard versus higher dosing of oseltamivir in critically ill patients with severe influenza. DATA SOURCES: An English-language literature search was conducted using MEDLINE (1966-February 2014) using the terms oseltamivir and influenza limited to humans and adults older than 19 years. Additional articles were identified through a manual search of the references obtained from the MEDLINE search...
August 2014: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/24811394/antiretroviral-and-medication-errors-in-hospitalized-hiv-positive-patients
#18
REVIEW
Emily H Li, Michelle M Foisy
OBJECTIVE: To summarize the literature regarding antiretroviral and other medication errors in hospitalized HIV-positive patients and to discuss potential interventions and solutions that have been studied to minimize drug error. DATA SOURCES: A systematic search of MEDLINE, PubMed, and EMBASE (2000-April 2014) was conducted. Search terms included HIV/AIDS, HAART, hospitalization, patient admission, inpatient, patient transfer, medication error, inappropriate prescribing, drug interaction, drug omission, drug toxicity, and contraindication...
August 2014: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/24570248/urinary-tract-infections-in-older-women-a-clinical-review
#19
REVIEW
Lona Mody, Manisha Juthani-Mehta
IMPORTANCE: Asymptomatic bacteriuria and symptomatic urinary tract infections (UTIs) in older women are commonly encountered in outpatient practice. OBJECTIVE: To review management of asymptomatic bacteriuria and symptomatic UTI and review prevention of recurrent UTIs in older community-dwelling women. EVIDENCE REVIEW: A search of Ovid (Medline, PsycINFO, Embase) for English-language human studies conducted among adults aged 65 years and older and published in peer-reviewed journals from 1946 to November 20, 2013...
February 26, 2014: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/24519479/effect-of-introducing-procalcitonin-on-antimicrobial-therapy-duration-in-patients-with-sepsis-and-or-pneumonia-in-the-intensive-care-unit
#20
Bryan M Bishop, John J Bon, Tamara L Trienski, Timothy R Pasquale, Bradley R Martin, Thomas M File
BACKGROUND: Utilizing procalcitonin (PCT) levels to limit antimicrobial overuse would be beneficial from a humanistic and economic perspective. OBJECTIVE: To assess whether introducing PCT at a teaching hospital reduced antimicrobial exposure in critically ill patients. METHODS: Patients wereadmitted to the intensive care unit (ICU) for >72 hours with sepsis and/or pneumonia. PCT levels were drawn on admission to the ICU or with new suspected infection, with at least 1 PCT level being drawn at least 48 hours later...
May 2014: Annals of Pharmacotherapy
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