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https://www.readbyqxmd.com/read/24419562/green-tea-ingestion-greatly-reduces-plasma-concentrations-of-nadolol-in-healthy-subjects
#1
RANDOMIZED CONTROLLED TRIAL
S Misaka, J Yatabe, F Müller, K Takano, K Kawabe, H Glaeser, M S Yatabe, S Onoue, J P Werba, H Watanabe, S Yamada, M F Fromm, J Kimura
This study aimed to evaluate the effects of green tea on the pharmacokinetics and pharmacodynamics of the β-blocker nadolol. Ten healthy volunteers received a single oral dose of 30 mg nadolol with green tea or water after repeated consumption of green tea (700 ml/day) or water for 14 days. Catechin concentrations in green tea and plasma were determined. Green tea markedly decreased the maximum plasma concentration (C(max)) and area under the plasma concentration-time curve (AUC(0-48)) of nadolol by 85...
April 2014: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/24011539/hrs-ehra-aphrs-expert-consensus-statement-on-the-diagnosis-and-management-of-patients-with-inherited-primary-arrhythmia-syndromes-document-endorsed-by-hrs-ehra-and-aphrs-in-may-2013-and-by-accf-aha-paces-and-aepc-in-june-2013
#2
REVIEW
Silvia G Priori, Arthur A Wilde, Minoru Horie, Yongkeun Cho, Elijah R Behr, Charles Berul, Nico Blom, Josep Brugada, Chern-En Chiang, Heikki Huikuri, Prince Kannankeril, Andrew Krahn, Antoine Leenhardt, Arthur Moss, Peter J Schwartz, Wataru Shimizu, Gordon Tomaselli, Cynthia Tracy
No abstract text is available yet for this article.
December 2013: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28664446/postnatal-outcomes-of-fetal-supraventricular-tachycardia-a-multicenter-study
#3
Kevin A Hinkle, Shabnam Peyvandi, Corey Stiver, Stacy A S Killen, Hsin Yi Weng, Susan P Etheridge, Michael D Puchalski
Supraventricular tachycardia (SVT), the most common fetal tachycardia, can be difficult to manage in utero. We sought to better understand predictors of the postnatal clinical course in neonates who experienced fetal SVT. We hypothesized that fetuses with hydrops or those with refractory SVT (failure of first-line SVT therapy) are more likely to experience postnatal SVT. This was a retrospective multicenter cohort study of subjects diagnosed with fetal SVT between 2006 and 2014. Fetuses with structural heart disease were excluded...
June 29, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28479512/long-term-prognosis-of-drug-induced-brugada-syndrome
#4
Juan Sieira, Giuseppe Ciconte, Giulio Conte, Carlo de Asmundis, Gian-Battista Chierchia, Giannis Baltogiannis, Giacomo Di Giovanni, Yukio Saitoh, Ruben Casado-Arroyo, Justo Juliá, Mark La Meir, Francis Wellens, Kristel Wauters, Gudrun Pappaert, Pedro Brugada
BACKGROUND: Patients with drug-induced Brugada syndrome (BS) are considered at a lower risk than those with a spontaneous type I pattern. Nevertheless, they can present arrhythmic events. OBJECTIVE: The purpose of this study was to investigate their clinical characteristics, long-term prognosis, and risk factors. METHODS: A consecutive cohort of 343 patients with drug-induced BS was included and compared with 78 patients with a spontaneous type I pattern...
May 4, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28450351/prospective-study-of-adenosine-on-atrioventricular-nodal-conduction-in-pediatric-and-young-adult-patients-after-heart-transplantation
#5
Jonathan N Flyer, Warren A Zuckerman, Marc E Richmond, Brett R Anderson, Tamar G Mendelsberg, Jennie M McAllister, Leonardo Liberman, Linda J Addonizio, Eric S Silver
BACKGROUND: Supraventricular tachycardia is common after heart transplantation. Adenosine, the standard therapy for treating supraventricular tachycardia in children and adults without transplantation, is relatively contraindicated after transplantation because of a presumed risk of prolonged atrioventricular block in denervated hearts. This study tested whether adenosine caused prolonged asystole after transplantation and if it was effective in blocking atrioventricular nodal conduction in these patients...
June 20, 2017: Circulation
https://www.readbyqxmd.com/read/28374048/lone-pediatric-atrial-fibrillation-in-the-united-states-analysis-of-over-1500-cases
#6
Iqbal El-Assaad, Sadeer G Al-Kindi, Elizabeth V Saarel, Peter F Aziz
Little is known about lone atrial fibrillation (AF) in pediatrics and its risk factors due to low prevalence. We sought to determine risk factors and estimate recurrence rates in children with lone AF using a large clinical database. Using the Explorys clinical database, we retrospectively identified patients who were below 20 years of age at the time of their AF diagnosis. Patients with congenital heart disease, cardiomyopathy, prior open heart surgery, or thyroid disease were excluded. Out of 7,969,230 children identified, 1910 had AF and 1570 met the definition of lone AF...
June 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28286245/pacing-as-a-treatment-for-reflex-mediated-vasovagal-situational-or-carotid-sinus-hypersensitivity-syncope-a-systematic-review-for-the-2017-acc-aha-hrs-guideline-for-the-evaluation-and-management-of-patients-with-syncope-a-report-of-the-american-college-of-cardiology
#7
Paul D Varosy, Lin Y Chen, Amy L Miller, Peter A Noseworthy, David J Slotwiner, Venkatesh Thiruganasambandamoorthy
OBJECTIVE: To determine, using systematic review of the biomedical literature, whether pacing reduces risk of recurrent syncope and relevant clinical outcomes among adult patients with reflex-mediated syncope. METHODS: MEDLINE (through PubMed), EMBASE, and the Cochrane Central Register of Controlled Trials (through October 7, 2015) were searched for randomized trials and observational studies examining pacing and syncope, and the bibliographies of known systematic reviews were also examined...
March 9, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28232261/impact-of-obesity-on-atrial-fibrillation-ablation-patient-characteristics-long-term-outcomes-and-complications
#8
Roger A Winkle, R Hardwin Mead, Gregory Engel, Melissa H Kong, William Fleming, Jonathan Salcedo, Rob A Patrawala
BACKGROUND: There is an association between obesity and atrial fibrillation (AF). The impact of obesity on AF ablation procedures is unclear. OBJECTIVE: The purpose of this study was to evaluate the influence of body mass index (BMI) on patient characteristics, long-term ablation outcomes, and procedural complications. METHODS: We evaluated 2715 patients undergoing 3742 AF ablation procedures. BMI was ≥30 kg/m(2) in 1058 (39%) and ≥40 kg/m(2) in 129 (4...
June 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28232263/progression-of-paroxysmal-to-persistent-atrial-fibrillation-canadian-registry-of-atrial-fibrillation-10-year-follow-up
#9
Gareth J Padfield, Christian Steinberg, Janice Swampillai, Hong Qian, Stuart J Connolly, Paul Dorian, Martin S Green, Karin H Humphries, George J Klein, Robert Sheldon, Mario Talajic, Charles R Kerr
BACKGROUND: Progression from paroxysmal to persistent atrial fibrillation (AF) has important clinical implications and is relevant to the management of patients with AF. OBJECTIVE: The purpose of this study was to define the long-term rate of progression from paroxysmal to persistent AF and the relevant clinical variables. METHODS: The Canadian Registry of Atrial Fibrillation enrolled patients after a first electrocardiographic diagnosis of paroxysmal AF...
February 21, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28058479/electrocardiographic-rr-and-qt-interval-variability-in-patients-with-atrial-septal-defect-and-healthy-children
#10
Yoshihiko Eryu, Tadayoshi Hata, Arisa Nagatani, Yuri Funamoto, Hidetoshi Uchida, Masayuki Fujino, Hiroko Boda, Masafumi Miyata, Tetsushi Yoshikawa
Atrial septal defect is a common congenital heart disease. In patients with atrial septal defect, left-to-right shunting increases the right atrial and right ventricular preload. This pathological change affects sinus node automaticity and myocardial depolarization and repolarization, and has the potential to evoke arrhythmogenic substrates. We examined the effect of atrial septal defect on sinus node automaticity and myocardial repolarization by investigating the variability in the repolarization interval, namely the QT variability index (QTVI) and variability ratio (VR)...
March 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/27885444/emergency-pacing-via-the-umbilical-vein-and-subsequent-permanent-pacemaker-implantation-in-a-neonate
#11
Xiao-Mei Li, Dong-Ya Zhang, Hong-Yin Li, Jun-Yi Wang, He Jiang, Guang-Zhi Jia, Hui Wu, Hai-Yan Ge
A dying neonate with congenital complete atrioventricular block underwent an emergency temporary pacing via the umbilical vein 1 h after birth. Implantation of a permanent epicardial pacemaker system was performed at the age of 10 days. During the follow-up period of 3 months, the child had been growing well with the VVIR pacemaker.
January 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/27855853/incidence-and-predictors-of-right-ventricular-pacing-induced-cardiomyopathy-in-patients-with-complete-atrioventricular-block-and-preserved-left-ventricular-systolic-function
#12
Erich L Kiehl, Tarek Makki, Rahul Kumar, Divya Gumber, Deborah H Kwon, John W Rickard, Mohamed Kanj, Oussama M Wazni, Walid I Saliba, Niraj Varma, Bruce L Wilkoff, Daniel J Cantillon
BACKGROUND: Right ventricular (RV) pacing may worsen left ventricular cardiomyopathy in patients with reduced left ventricular ejection fraction (LVEF) and advanced atrioventricular block. OBJECTIVE: The objectives of this study were to calculate incidence and identify predictors of RV pacing-induced cardiomyopathy (PICM) in complete heart block (CHB) with preserved LVEF and to describe outcomes of subsequent cardiac resynchronization therapy (CRT) upgrade. METHODS: An analysis of consecutive patients receiving permanent pacemaker (PPM) from 2000 to 2014 for CHB with LVEF >50% was performed...
December 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/24814377/paces-hrs-expert-consensus-statement-on-the-recognition-and-management-of-arrhythmias-in-adult-congenital-heart-disease-developed-in-partnership-between-the-pediatric-and-congenital-electrophysiology-society-paces-and-the-heart-rhythm-society-hrs-endorsed-by
#13
Paul Khairy, George F Van Hare, Seshadri Balaji, Charles I Berul, Frank Cecchin, Mitchell I Cohen, Curt J Daniels, Barbara J Deal, Joseph A Dearani, Natasja de Groot, Anne M Dubin, Louise Harris, Jan Janousek, Ronald J Kanter, Peter P Karpawich, James C Perry, Stephen P Seslar, Maully J Shah, Michael J Silka, John K Triedman, Edward P Walsh, Carole A Warnes
No abstract text is available yet for this article.
October 2014: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27659101/beta-blocker-therapy-for-long-qt-syndrome-and-catecholaminergic-polymorphic-ventricular-tachycardia-are-all-beta-blockers-equivalent
#14
Michael J Ackerman, Silvia G Priori, Anne M Dubin, Peter Kowey, Nicholas J Linker, David Slotwiner, John Triedman, George F Van Hare, Michael R Gold
No abstract text is available yet for this article.
January 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27651369/high-g-force-rollercoaster-rides-induce-sinus-tachycardia-but-no-cardiac-arrhythmias-in-healthy-children
#15
Guido E Pieles, Victoria Husk, Teresa Blackwell, Deirdre Wilson, Simon M Collin, Craig A Williams, A Graham Stuart
Theme park operators and medical professionals advise children with heart conditions against using rollercoaster rides, but these recommendations are not evidence-based. The underlying assumption is that the combination of adrenergic stimulation through stress and acceleration might trigger arrhythmias in susceptible individuals. We conducted a cross-sectional observational study to assess heart rate and rhythm in healthy children during commercial rollercoaster rides. Twenty healthy children (9 male) aged 11-15 (mean 13...
January 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/27591826/hemoglobin-a1c-levels-and-risk-of-sudden-cardiac-death-a-nested-case-control-study
#16
Ravi B Patel, M V Moorthy, Stephanie E Chiuve, Aruna D Pradhan, Nancy R Cook, Christine M Albert
BACKGROUND: Sudden cardiac death (SCD) is often the first manifestation of cardiovascular disease (CVD), and preventive strategies within this broad population are lacking. Patients with diabetes represent a high-risk subgroup, but few data exist regarding whether measures of glycemia mediate risk and/or add to SCD risk stratification. OBJECTIVE: The purpose of this study was to examine the association between hemoglobin A1c (HbA1c) and SCD. METHODS: We performed a case-control analysis among individuals enrolled in 6 prospective cohort studies...
January 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/24685669/2014-aha-acc-hrs-guideline-for-the-management-of-patients-with-atrial-fibrillation-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-practice-guidelines-and-the-heart-rhythm-society
#17
REVIEW
Craig T January, L Samuel Wann, Joseph S Alpert, Hugh Calkins, Joaquin E Cigarroa, Joseph C Cleveland, Jamie B Conti, Patrick T Ellinor, Michael D Ezekowitz, Michael E Field, Katherine T Murray, Ralph L Sacco, William G Stevenson, Patrick J Tchou, Cynthia M Tracy, Clyde W Yancy
No abstract text is available yet for this article.
December 2, 2014: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27453127/a-prospective-5-year-study-of-the-frequency-of-arrhythmias-during-serial-exercise-testing-and-clinical-follow-up-after-melody-valve-implant
#18
Bryant Priromprintr, Michael J Silka, Jonathan Rhodes, Anjan S Batra
BACKGROUND: Although percutaneous Melody valve implant has become an accepted alternative to surgical pulmonary valve replacement in patients with congenital heart disease, the benefit regarding frequency and severity of arrhythmias remains undefined. OBJECTIVE: The purpose of this study was to evaluate the impact of Melody valve implant on the type and frequency of arrhythmias during cardiopulmonary exercise testing (CPET) and subsequent clinical outcome. METHODS: As part of the phase I Melody valve clinical trial, 136 patients with congenital heart disease underwent prospective serial evaluation including CPET before implant, 6 months after implant, and annually thereafter for 5 years...
November 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27435587/use-of-dofetilide-in-adult-patients-with-atrial-arrhythmias-and-congenital-heart-disease-a-paces-collaborative-study
#19
Iqbal El-Assaad, Sadeer G Al-Kindi, JoEllyn Abraham, Shubhayan Sanatani, David J Bradley, Colby Halsey, Ian H Law, Seshadri Balaji, Ira Shetty, Peter F Aziz
BACKGROUND: Arrhythmia management has become the major treatment challenge in adult patients with congenital heart disease (ACHD). OBJECTIVE: We sought to investigate the utility and safety profile of dofetilide for atrial arrhythmias in ACHD. METHODS: A retrospective chart review was performed. We included patients (age ≥18 years) with congenital heart disease who had atrial fibrillation (AF) or intra-atrial reentrant tachycardia treated with dofetilide...
October 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27421846/the-risk-of-thromboembolic-complications-in-fontan-patients-with-atrial-flutter-fibrillation-treated-with-electrical-cardioversion
#20
Jiuann-Huey I Lin, Adam C Kean, Timothy M Cordes
Atrial flutter or fibrillation (AFF) remains a major chronic complication of the Fontan procedure. This complication further predisposes this patient population to thromboembolic events. However, the incidence of thromboembolic complications in Fontan patients with AFF prior to or acutely after electrical cardioversion is unknown. This study aimed to characterize the risk of post-cardioversion thromboembolic events in this population. We performed a retrospective medical record review of all patients with a history of Fontan operation treated with direct current cardioversion for AFF at Riley Children's Hospital between June 1992 and March 2014...
October 2016: Pediatric Cardiology
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