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REVIEW
Hai Meng, Qi Fei, Bingqiang Wang, Yong Yang, Dong Li, Jinjun Li, Nan Su
BACKGROUND: Epidural injections of anesthetic with or without steroids are widely used for treating lumbar spinal stenosis, a common cause of chronic low back pain, but there is a lack of rigorous data comparing the effectiveness of epidural injections of anesthetic with and without steroids. This meta-analysis presents a current, comprehensive picture of how epidural injections of anesthetic with steroids compare with those using local anesthetic alone. METHODS: PubMed, Embase, Web of Science, and Cochrane Library databases were searched from their inception through February 5, 2015...
2015: Drug Design, Development and Therapy
#2
REVIEW
Laxmaiah Manchikanti, Ramsin M Benyamin, Frank J E Falco, Alan D Kaye, Joshua A Hirsch
BACKGROUND: As part of a comprehensive nonsurgical approach, epidural injections often are used in the management of lumbar disc herniation. Recent guidelines and systematic reviews have reached different conclusions about the efficacy of epidural injections in managing lumbar disc herniation. QUESTIONS/PURPOSES: In this systematic review, we determined the efficacy (pain relief and functional improvement) of the three anatomic approaches (caudal, lumbar interlaminar, and transforaminal) for epidural injections in the treatment of disc herniation...
June 2015: Clinical Orthopaedics and related Research
#3
REVIEW
Jo Nijs, Adri Apeldoorn, Hank Hallegraeff, Jacqui Clark, Rob Smeets, Annaleen Malfliet, Enrique L Girbes, Margot De Kooning, Kelly Ickmans
BACKGROUND: Low back pain (LBP) is a heterogeneous disorder including patients with dominant nociceptive (e.g., myofascial low back pain), neuropathic (e.g., lumbar radiculopathy), and central sensitization pain. In order to select an effective and preferably also efficient treatment in daily clinical practice, LBP patients should be classified clinically as either predominantly nociceptive, neuropathic, or central sensitization pain. OBJECTIVE: To explain how clinicians can differentiate between nociceptive, neuropathic, and central sensitization pain in patients with LBP...
2015: Pain Physician
#4
REVIEW
Laxmaiah Manchikanti, Alan D Kaye, Mark V Boswell, Sanjay Bakshi, Christopher G Gharibo, Vahid Grami, Jay S Grider, Sanjeeva Gupta, Sachin Sunny Jha, Dharam P Mann, Devi E Nampiaparampil, Manohar Lal Sharma, Lindsay N Shroyer, Vijay Singh, Amol Soin, Ricardo Vallejo, Bradley W Wargo, Joshua A Hirsch
BACKGROUND: The therapeutic spinal facet joint interventions generally used for the treatment of axial spinal pain of facet joint origin are intraarticular facet joint injections, facet joint nerve blocks, and radiofrequency neurotomy. Despite interventional procedures being common as treatment strategies for facet joint pathology, there is a paucity of literature investigating these therapeutic approaches. Systematic reviews assessing the effectiveness of various therapeutic facet joint interventions have shown there to be variable evidence based on the region and the modality of treatment utilized...
2015: Pain Physician
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