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Bias en IECA

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Brennan C Kahan, Sunita Rehal, Suzie Cro
OBJECTIVE: Unblinded outcome assessment can lead to biased estimates of treatment effect in randomised trials. We reviewed published trials to assess how often blinded assessment is used, and whether its use varies according to the type of outcome or assessor. DESIGN AND SETTING: A review of parallel group, individually randomised phase III trials published in four general medical journals (BMJ, Journal of the American Medical Association, The Lancet, and New England Journal of Medicine) in 2010...
2015: PloS One
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