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Clare Gilbert, Richard Wormald, Alistair Fielder, Ashok Deorari, Luz Consuelo Zepeda-Romero, Graham Quinn, Anand Vinekar, Andrea Zin, Brian Darlow
No abstract text is available yet for this article.
January 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
Ann Hellström, Lois E H Smith, Olaf Dammann
The immature retinas of preterm neonates are susceptible to insults that disrupt neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors due to hyperoxia and loss of the maternal-fetal interaction result in an arrest of retinal vascularisation (phase 1). Subsequently, the increasingly metabolically active, yet poorly vascularised, retina becomes hypoxic, stimulating growth factor-induced vasoproliferation (phase 2), which can cause retinal detachment. In very premature infants, controlled oxygen administration reduces but does not eliminate retinopathy of prematurity...
October 26, 2013: Lancet
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