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RANDOMIZED CONTROLLED TRIAL
Peter J D Andrews, H Louise Sinclair, Aryelly Rodriguez, Bridget A Harris, Claire G Battison, Jonathan K J Rhodes, Gordon D Murray
BACKGROUND: In patients with traumatic brain injury, hypothermia can reduce intracranial hypertension. The benefit of hypothermia on functional outcome is unclear. METHODS: We randomly assigned adults with an intracranial pressure of more than 20 mm Hg despite stage 1 treatments (including mechanical ventilation and sedation management) to standard care (control group) or hypothermia (32 to 35°C) plus standard care. In the control group, stage 2 treatments (e...
December 17, 2015: New England Journal of Medicine
#2
MULTICENTER STUDY
Aaron J Dawes, Greg D Sacks, H Gill Cryer, J Peter Gruen, Christy Preston, Deidre Gorospe, Marilyn Cohen, David L McArthur, Marcia M Russell, Melinda Maggard-Gibbons, Clifford Y Ko
BACKGROUND: Although intracranial pressure (ICP) monitoring in severe traumatic brain injury (TBI) is recommended by the Brain Trauma Foundation, the benefits remain controversial. We sought to determine the impact of ICP monitor placement on inpatient mortality within a regional trauma system after correcting for selection bias through propensity score matching. METHODS: Data were collected on all severe TBI cases presenting to 14 trauma centers during the 2-year study period (2009-2010)...
March 2015: Journal of Trauma and Acute Care Surgery
#3
JOURNAL ARTICLE
Konstantinos Chouliaras, Elias Bench, Peep Talving, Aaron Strumwasser, Elizabeth Benjamin, Lydia Lam, Kenji Inaba, Demetrios Demetriades
BACKGROUND: Incidental pneumomediastinum is a common radiologic finding following blunt thoracic injury; however, the clinical significance of pneumomediastinum on screening imaging is poorly defined (Curr Probl Surg. 2004;41(3):211-380; Injury. 2010;41(1):40-43). The purpose of this study was to define the incidence of aerodigestive injuries in patients with pneumomediastinum after blunt thoracic and neck injury. METHODS: After institutional review board approval was obtained, a retrospective review was performed of all patients admitted to Los Angeles County + University of Southern California Medical Center with blunt neck and/or thoracic injuries between January 2007 and December 2012...
August 2015: Journal of Trauma and Acute Care Surgery
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