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Outstanding Clinical Review

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672 papers 500 to 1000 followers Topics related to cardiac anesthesia & critical care
https://www.readbyqxmd.com/read/29927776/critical-care-management-of-anti-n-methyl-d-asparate-receptor-encephalitis
#1
Ron R Neyens, George E Gaskill, Julio A Chalela
OBJECTIVES: Anti-N-methyl-D-asparate receptor encephalitis is considered an immune-mediated form of encephalitis with paraneoplastic and nonparaneoplastic forms. Delay in recognition is common and patients typically present to the ICU without a diagnosis or with complications following a delayed diagnosis. The aim of this review is to provide a focused overview for the ICU clinician regarding presentation, diagnosis, and critical care management. DATA SOURCES, STUDY SELECTION, AND DATA EXTRACTION: PubMed database search with manual review of articles involving anti-N-methyl-D-asparate receptor encephalitis...
June 20, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29741250/how-i-investigate-for-bleeding-disorders
#2
REVIEW
C P M Hayward
INTRODUCTION: Laboratory investigations for bleeding disorders are warranted when an individual has a personal and/or family history of bleeding, and/or laboratory findings that suggest the possibility of an inherited or acquired bleeding disorder. METHODS: This review summarizes author's experience with ordering and reporting on diagnostic investigations for common and rare bleeding disorders, with consideration of recent articles on diagnosing bleeding disorders...
May 2018: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/29909110/comprehensive-echocardiographic-assessment-of-normal-transcatheter-valve-function
#3
Rebecca T Hahn, Jonathon Leipsic, Pamela S Douglas, Wael A Jaber, Neil J Weissman, Philippe Pibarot, Philipp Blanke, Jae K Oh
OBJECTIVES: This study aims to establish parameters for identifying normal function for each of the 3 iterations of balloon-expandable valves and 2 iterations of self-expanding valves. BACKGROUND: Expected transthoracic echocardiographic Doppler-derived hemodynamic data for transcatheter aortic valves inform pre-implant decision-making and post-implanted monitoring of longitudinal valve function. METHODS: We collected the Echocardiography Core Lab measured mean gradients and effective orifice area (EOA) from discharge or 30-day echocardiograms from randomized trials; the PARTNER (Placement of Aortic Transcatheter Valves) trials for the balloon-expandable valves and the Medtronic CoreValve US Pivotal trial and Medtronic CoreValve Evolut R United States IDE Clinical Study for the self-expanding valves...
June 8, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29907121/position-of-draining-venous-cannula-in-extracorporeal-membrane-oxygenation-for-respiratory-and-respiratory-circulatory-support-in-adult-patients
#4
B Frenckner, M Broman, M Broomé
Extracorporeal membrane oxygenation (ECMO) is used in critically ill patients with severe pulmonary and/or cardiac failure. Blood is drained from the venous system and pumped through a membrane oxygenator where it is oxygenated. For pulmonary support, the blood is returned to the patient via a vein (veno-venous ECMO) and for pulmonary/circulatory support it is returned via an artery (veno-arterial ECMO).Veno-venous ECMO can be performed either with a single dual-lumen cannula or with two separate single-lumen cannulas...
June 15, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29908153/testing-for-respiratory-viruses-in-adults-with-severe-lower-respiratory-infection
#5
REVIEW
James M Walter, Richard G Wunderink
Viral pathogens are a common cause of severe lower respiratory tract infection (LRTI) in adults. Our ability to rapidly and accurately identify viral infections has dramatically improved as slow culture-based techniques have been largely replaced by multiplex high-throughput systems. Given these advances, reevaluation of the role of respiratory viral testing in adults presenting with LRTI is important. We review potential benefits of testing, provide an overview of the most commonly used diagnostic techniques, and consider whether current evidence supports routine testing...
June 13, 2018: Chest
https://www.readbyqxmd.com/read/29903350/acute-limited-intimal-tears-of-the-thoracic-aorta
#6
Anne S Chin, Martin J Willemink, Aya Kino, Virginia Hinostroza, Anna M Sailer, Michael P Fischbein, R Scott Mitchell, Gerald J Berry, D Craig Miller, Dominik Fleischmann
BACKGROUND: Limited intimal tears (LITs) of the aorta (Class 3 dissection variant) are the least common form of aortic pathology in patients presenting with acute aortic syndrome (AAS). LITs are difficult to detect on imaging and may be underappreciated. OBJECTIVES: This study sought to describe the frequency, pathology, treatment, and outcome of LITs compared with other AAS, and to demonstrate that LITs can be detected pre-operatively by contemporary imaging. METHODS: The authors retrospectively reviewed 497 patients admitted for 513 AAS events at a single academic aortic center between 2003 and 2012...
June 19, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29895296/thrombocytopenia-in-the-icu-disseminated-intravascular-coagulation-and-thrombotic-microangiopathies-what-intensivists-need-to-know
#7
EDITORIAL
Jean-Louis Vincent, Pedro Castro, Beverley J Hunt, Achim Jörres, Manuel Praga, Jose Rojas-Suarez, Eizo Watanabe
No abstract text is available yet for this article.
June 13, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29889937/type-2-myocardial-infarction-diagnosis-prognosis-and-treatment
#8
Cian P McCarthy, Muthiah Vaduganathan, James L Januzzi
No abstract text is available yet for this article.
June 11, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29736167/mechanisms-and-management-of-acute-pancreatitis
#9
REVIEW
Ari Garber, Catherine Frakes, Zubin Arora, Prabhleen Chahal
Acute pancreatitis represents a disorder characterized by acute necroinflammatory changes of the pancreas and is histologically characterized by acinar cell destruction. Diagnosed clinically with the Revised Atlanta Criteria, and with alcohol and cholelithiasis/choledocholithiasis as the two most prominent antecedents, acute pancreatitis ranks first amongst gastrointestinal diagnoses requiring admission and 21st amongst all diagnoses requiring hospitalization with estimated costs approximating 2.6 billion dollars annually...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29871657/prognostication-after-cardiac-arrest
#10
REVIEW
Claudio Sandroni, Sonia D'Arrigo, Jerry P Nolan
Hypoxic-ischaemic brain injury (HIBI) is the main cause of death in patients who are comatose after resuscitation from cardiac arrest. A poor neurological outcome-defined as death from neurological cause, persistent vegetative state, or severe neurological disability-can be predicted in these patients by assessing the severity of HIBI. The most commonly used indicators of severe HIBI include bilateral absence of corneal and pupillary reflexes, bilateral absence of N2 O waves of short-latency somatosensory evoked potentials, high blood concentrations of neuron specific enolase, unfavourable patterns on electroencephalogram, and signs of diffuse HIBI on computed tomography or magnetic resonance imaging of the brain...
June 5, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29853518/clinical-outcome-of-degenerative-mitral-regurgitation-critical-importance-of-echocardiographic-quantitative-assessment-in-routine-practice
#11
Clemence Antoine, Giovanni Benfari, Hector I Michelena, Joseph F Malouf, Vuyisile T Nkomo, Prabin Thapa, Maurice Enriquez-Sarano
Background -Echocardiographic quantitation of degenerative mitral regurgitation (DMR) is recommended whenever possible in clinical guidelines but is criticized and its scalability to routine clinical practice doubted. We hypothesized that echocardiographic DMR quantitation, performed in routine clinical practice by multiple practitioners predicts independently long-term survival, and thus is essential to DMR management. Methods -We included patients diagnosed with isolated mitral-valve-prolapse 2003-2011 and any degree of MR quantified by any physician/sonographer in routine clinical practice...
May 31, 2018: Circulation
https://www.readbyqxmd.com/read/29843753/mechanical-cpr-who-when-how
#12
REVIEW
Kurtis Poole, Keith Couper, Michael A Smyth, Joyce Yeung, Gavin D Perkins
In cardiac arrest, high quality cardiopulmonary resuscitation (CPR) is a key determinant of patient survival. However, delivery of effective chest compressions is often inconsistent, subject to fatigue and practically challenging.Mechanical CPR devices provide an automated way to deliver high-quality CPR. However, large randomised controlled trials of the routine use of mechanical devices in the out-of-hospital setting have found no evidence of improved patient outcome in patients treated with mechanical CPR, compared with manual CPR...
May 29, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29843791/the-role-of-adrenaline-in-cardiopulmonary-resuscitation
#13
REVIEW
Christopher J R Gough, Jerry P Nolan
Adrenaline has been used in the treatment of cardiac arrest for many years. It increases the likelihood of return of spontaneous circulation (ROSC), but some studies have shown that it impairs cerebral microcirculatory flow. It is possible that better short-term survival comes at the cost of worse long-term outcomes. This narrative review summarises the rationale for using adrenaline, significant studies to date, and ongoing research.
May 29, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29804686/transesophageal-echocardiographic-assessment-of-the-sutureless-perceval-aortic-valve
#14
REVIEW
Adam A Dalia, Caroline Hunter, Elliot Woodward, David Dudzinski, Michael Andritsos, Michael Essandoh, Michael Andrawes
No abstract text is available yet for this article.
April 26, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29678608/clinical-and-hemodynamic-effects-of-intra-aortic-balloon-pump-therapy-in-chronic-heart-failure-patients-with-cardiogenic-shock
#15
Justin A Fried, Abhinav Nair, Koji Takeda, Kevin Clerkin, Veli K Topkara, Amirali Masoumi, Melana Yuzefpolskaya, Hiroo Takayama, Yoshifumi Naka, Daniel Burkhoff, Ajay Kirtane, S M Dimitrios Karmpaliotis, Jeffrey Moses, Paolo C Colombo, A Reshad Garan
BACKGROUND: The role of the intra-aortic balloon pump (IABP) in acute decompensated heart failure (HF) with cardiogenic shock (CS) is largely undefined. In this study we sought to assess the hemodynamic and clinical response to IABP in chronic HF patients with CS and identify predictors of response to this device. METHODS: We retrospectively reviewed all patients undergoing IABP implantation from 2011 to 2016 at our institution to identify chronic HF patients with acute decompensation and CS (cardiac index <2...
March 20, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29754310/the-ten-pitfalls-of-lactate-clearance-in-sepsis
#16
Glenn Hernandez, Rinaldo Bellomo, Jan Bakker
No abstract text is available yet for this article.
May 12, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29757781/misconceptions-surrounding-penicillin-allergy-implications-for-anesthesiologists
#17
Leon Vorobeichik, Elizabeth A Weber, Jordan Tarshis
Administration of preoperative antimicrobial prophylaxis, often with a cephalosporin, is the mainstay of surgical site infection prevention guidelines. Unfortunately, due to prevalent misconceptions, patients labeled as having a penicillin allergy often receive alternate and less-effective antibiotics, placing them at risk of a variety of adverse effects including increased morbidity and higher risk of surgical site infection. The perioperative physician should ascertain the nature of previous reactions to aid in determining the probability of the prevalence of a true allergy...
May 10, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29769006/role-of-cardiac-catheterization-lab-post-resuscitation-in-patients-with-st-elevation-myocardial-infarction
#18
Sridhar Reddy, Kwan S Lee, Karl Kern, Kapildeo Lotun
BACKGROUND: Cardiac arrest remains a common and lethal condition associated with high morbidity and mortality. Even with improving survival rates, the successfully resuscitated post cardiac arrest patient is also at risk for poor neurological outcomes, functional status and long- term survival if not managed appropriately. Given that acute coronary occlusion has been found to be the leading cause of cardiac arrest, long-term prognosis is good in selected patients after successful out-of-hospital resuscitation and ST elevation myocardial infarction who are taken for immediate coronary angiography, treated with primary percutaneous coronary intervention and hypothermia when indicated...
May 16, 2018: Current Cardiology Reviews
https://www.readbyqxmd.com/read/29750686/physiologic-basis-for-venovenous-extracorporeal-membrane-oxygenation-management
#19
Hoong Sern Lim
No abstract text is available yet for this article.
May 7, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29502716/recent-advances-in-the-acute-management-of-intracerebral-hemorrhage
#20
REVIEW
Joseph D Burns, Jennifer L Fisher, Anna M Cervantes-Arslanian
Primary intracerebral hemorrhage (ICH) is a common, devastating disease that lacks an effective specific treatment. Mortality is high, functional outcomes are poor, and these have not substantially changed for decades. There is, therefore, considerable opportunity for advancement in the management of ICH. In recent years, a significant amount of research has begun to address this gap. This article is aimed at updating neurologists on the most clinically relevant contemporary research.
April 2018: Neurosurgery Clinics of North America
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