Lu Huber, Nils Lachmann, Michael Dürr, Mareen Matz, Lutz Liefeldt, Hans-H Neumayer, Constanze Schönemann, Klemens Budde
Sensitization is generally referred to as the development of alloantibodies, specifically anti-human leukocyte antigen (HLA) immunoglobulin G (IgG) antibodies, most commonly caused by pregnancy, blood transfusion or a previous transplant. Despite being a well known phenomenon, there has not been a general consensus on its definition, monitoring or management. Today, 25% of the patients waitlisted for kidney transplant in the US have a panel reactive antibody (PRA) of >10% while, in the Eurotransplant zone, 14% have a PRA of >5%...
July 9, 2012: Drugs