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Chronic Pain

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7 papers 0 to 25 followers
Chris Littlewood, Peter Malliaras, Marcus Bateman, Richmond Stace, Stephen May, Stephen Walters
Tendinopathy is a term used to describe a painful tendon disorder but despite being a well-recognised clinical presentation, a definitive understanding of the pathoaetiology of rotator cuff tendinopathy remains elusive. Current explanatory models, which relate to peripherally driven nocioceptive mechanisms secondary to structural abnormality, or failed healing, appear inadequate on their own in the context of current literature. In light of these limitations this paper presents an extension to current models that incorporates the integral role of the central nervous system in the pain experience...
December 2013: Manual Therapy
Jo Nijs, Rafael Torres-Cueco, C Paul van Wilgen, Enrique Lluh Girbes, Filip Struyf, Nathalie Roussel, Jessica van Oosterwijck, Liesbeth Daenen, Kevin Kuppens, Luc Vanwerweeen, Linda Hermans, David Beckwee, Lennard Voogt, Jacqui Clark, Niamh Moloney, Mira Meeus
BACKGROUND: The awareness is growing that central sensitization is of prime importance for the assessment and management of chronic pain, but its classification is challenging clinically since no gold standard method of assessment exists. OBJECTIVES: Designing the first set of classification criteria for the classification of central sensitization pain. METHODS: A body of evidence from original research papers was used by 18 pain experts from 7 different countries to design the first classification criteria for central sensitization pain...
September 2014: Pain Physician
Tom G Mayer, Randy Neblett, Howard Cohen, Krista J Howard, Yun H Choi, Mark J Williams, Yoheli Perez, Robert J Gatchel
Central sensitization (CS) has been proposed as a common pathophysiological mechanism to explain related syndromes for which no specific organic cause can be found. The term "central sensitivity syndrome (CSS)" has been proposed to describe these poorly understood disorders related to CS. The goal of this investigation was to develop the Central Sensitization Inventory (CSI), which identifies key symptoms associated with CSSs and quantifies the degree of these symptoms. The utility of the CSI, to differentiate among different types of chronic pain patients who presumably have different levels of CS impairment, was then evaluated...
April 2012: Pain Practice: the Official Journal of World Institute of Pain
Randy Neblett, Meredith M Hartzell, Howard Cohen, Tom G Mayer, Mark Williams, YunHee Choi, Robert J Gatchel
OBJECTIVES: The aim of this study was to determine the ability of the central sensitization inventory (CSI), a new screening instrument, to assist clinicians in identifying patients with central sensitivity syndromes (CSSs). METHODS: Patients from a psychiatric medical practice (N=161), which specialized in the assessment and treatment of complex pain and psychophysiological disorders, were assessed for the presence of a CSS. CSI scores, using a previously determined cutoff of "40" of "100," were compared between the CSS patient group (n=99) and the non-CSS patient group (n=62)...
April 2015: Clinical Journal of Pain
Randy Neblett, Howard Cohen, YunHee Choi, Meredith M Hartzell, Mark Williams, Tom G Mayer, Robert J Gatchel
UNLABELLED: Central sensitization (CS) is a proposed physiological phenomenon in which central nervous system neurons become hyperexcitable, resulting in hypersensitivity to both noxious and non-noxious stimuli. The term central sensitivity syndrome (CSS) describes a group of medically indistinct (or nonspecific) disorders, such as fibromyalgia, chronic fatigue syndrome, and irritable bowel syndrome, for which CS may be a common etiology. In a previous study, the Central Sensitization Inventory (CSI) was introduced as a screening instrument for clinicians to help identify patients with a CSS...
May 2013: Journal of Pain: Official Journal of the American Pain Society
Julius H Bourke, Richard M Langford, Peter D White
OBJECTIVES: Functional somatic syndromes are common and disabling conditions that all include chronic pain, and which may be related to central nervous system sensitisation. Here, we address the concept of central sensitisation as a physiological basis for the functional somatic syndromes. METHODS: A narrative review of the current literature on central sensitisation and physiological studies in the functional somatic syndromes. RESULTS: Central sensitisation may be a common neurophysiological process that is able to explain non-painful as well as painful symptoms in these disorders...
March 2015: Journal of Psychosomatic Research
Jo Nijs, Anneleen Malfliet, Kelly Ickmans, Isabel Baert, Mira Meeus
INTRODUCTION: Central sensitization (CS) is present in a variety of chronic pain disorders, including whiplash, temporomandibular disorders, low back pain, osteoarthritis, fibromyalgia, headache, lateral epicondylalgia among others. In spite of our increased understanding of the mechanisms involved in CS pain, its treatment remains a challenging issue. AREAS COVERED: An overview of the treatment options we have for desensitising the CNS in patients with CS pain is provided...
August 2014: Expert Opinion on Pharmacotherapy
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