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Interesante

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677 papers 100 to 500 followers
https://www.readbyqxmd.com/read/28092913/umbilical-venous-catheter-malposition-is-associated-with-necrotizing-enterocolitis-in-premature-infants
#1
Mustafa Sulemanji, Khashayar Vakili, David Zurakowski, Wayne Tworetzky, Steven J Fishman, Heung Bae Kim
OBJECTIVE: The etiology of necrotizing enterocolitis (NEC) remains elusive despite known associations with several factors, including intestinal ischemia related to the effects of umbilical arterial catheterization on the mesenteric circulation. However, the role of the mesenteric venous circulation has yet to be studied as a potential cause of NEC. We examined the association between umbilical venous catheter (UVC) position and the development of NEC in premature infants. DESIGN: A prospective cohort study was performed to examine the effect of UVC on portosystemic shunting via the ductus venosus (DV) and its potential role in NEC...
January 17, 2017: Neonatology
https://www.readbyqxmd.com/read/28109705/renal-function-in-the-fetus-and-neonate-the-creatinine-enigma
#2
REVIEW
Justin T Kastl
The use of serum creatinine levels to estimate glomerular function in infants is admittedly fraught with inherent inaccuracies which are both physiological and methodological in nature. This characteristic can understandably reduce the neonatal clinician's confidence in the ability of serum creatinine levels to provide useful information relevant to their patients' medical care. The aim of this review is to provide further insight into the peculiarities of serum creatinine trends in both premature and term infants with special focus on the maturational and developmental changes occurring in the kidney during this crucial time-period...
January 18, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28114704/early-commencement-of-enteral-feeds-in-gastroschisis-a-systematic-review-of-literature
#3
Madhuri Dama, Uday Rao, Ian Gollow, Max Bulsara, Shripada Rao
Introduction There are no evidence-based strategies to improve feed tolerance in gastroschisis. Early commencement of enteral feeds (CEF) is known to improve feed tolerance in preterm infants. It is possible that infants with gastroschisis may also benefit from early CEF. Objectives To conduct a systematic review to evaluate the relationship between time of CEF, and time to reach full enteral feeds (FEF), duration of parenteral nutrition (PN), and duration of hospital stay (HS). Methods PubMed, EMBASE, Cochrane CENTRAL, and relevant conference abstracts were searched in December 2015...
January 23, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28135431/retrospective-dual-center-study-of-parenteral-nutrition-associated-cholestasis-in-premature-neonates
#4
Weihui Yan, Li Hong, Ying Wang, Yi Feng, Lina Lu, Yijing Tao, Jiang Wu, Huijuan Ruan, Qingya Tang, Wei Cai
BACKGROUND: The pathogenesis of parenteral nutrition-associated cholestasis (PNAC) has not been clarified. The objective of this study was to explore the incidence of PNAC in premature infants without surgery and to identify associated risk factors. MATERIALS AND METHODS: Premature neonates who received parenteral nutrition (PN) at least 14 days were included in a retrospective, dual-center study. Cholestasis was diagnosed as conjugated bilirubin ≥2 mg/dL. Infants with metabolic liver disease, cyanotic congenital heart disease, congenital syphilis, hepadnaviridae infection, and those who underwent surgery were excluded...
January 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/27849656/the-use-of-nesiritide-in-children-with-congenital-heart-disease
#5
Ronald A Bronicki, Michele Domico, Paul A Checchia, Curtis E Kennedy, Ayse Akcan-Arikan
OBJECTIVE: We evaluated the use of nesiritide in children with critical congenital heart disease, pulmonary congestion, and inadequate urine output despite conventional diuretic therapy. DESIGN: We conducted a retrospective analysis of 26 consecutive patients, comprising 37 infusions occurring during separate hospitalizations. Hemodynamic variables, urine output, and serum creatinine levels were monitored prior to and throughout the duration of therapy with nesiritide...
February 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28148712/abdominal-masses
#6
EDITORIAL
Nicholas M Potisek, James W Antoon
No abstract text is available yet for this article.
February 2017: Pediatrics in Review
https://www.readbyqxmd.com/read/28004188/comparative-study-of-the-efficacy-and-safety-of-paracetamol-ibuprofen-and-indomethacin-in-closure-of-patent-ductus-arteriosus-in-preterm-neonates
#7
Abd El-Rahman El-Mashad, Heba El-Mahdy, Doaa El Amrousy, Marwa Elgendy
: In this prospective study, we compared the efficacy and side effects of indomethacin, ibuprofen, and paracetamol in patent ductus arteriosus (PDA) closure in preterm neonates. Three hundred preterm neonates with hemodynamically significant PDA (hs-PDA) admitted at our neonatal intensive care unit were enrolled in the study. They were randomized into three groups. Group I (paracetamol group) received 15 mg/kg/6 h IV paracetamol infusion for 3 days. Group II (ibuprofen group) received 10 mg/kg IV ibuprofen infusion followed by 5 mg/kg/day for 2 days...
February 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28145021/probiotics-for-prevention-of-suspected-sepsis-in-low-birthweight-infants
#8
Anu Thukral, Mari Jeeva Sankar
No abstract text is available yet for this article.
January 31, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28085236/budesonide-reduces-hospital-admission-rates-in-preschool-children-with-acute-wheezing
#9
Cem Hasan Razi, Nazlı Cörüt, Nesibe Andıran
The object of this study was to determine whether high doses of inhaled budesonide provide additional benefits to a standardized treatment regimen that includes systemic steroids and salbutamol in preschool patients presented to the emergency department (ED) with acute wheezing attacks. Methods This randomized, double-blind, placebo-controlled, parallel group trial was conducted in children, 6 months-6 years with moderate or severe acute wheezing epizode, as determined based on a pulmonary index score (PIS) of 7-13 points...
January 13, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28009655/amiodarone-versus-lidocaine-for-pediatric-cardiac-arrest-due-to-ventricular-arrhythmias-a-systematic-review
#10
Mary E McBride, Bradley S Marino, Gregory Webster, Jesús Lopez-Herce, Carolyn P Ziegler, Allan R De Caen, Dianne L Atkins
OBJECTIVE: We performed a systematic review as part of the International Liaison Committee on Resuscitation process to create a consensus on science statement regarding amiodarone or lidocaine during pediatric cardiac arrest for the 2015 International Liaison Committee on Resuscitation's Consensus on Science and Treatment Recommendations. DATA SOURCES: Studies were identified from comprehensive searches in PubMed, Embase, and the Cochrane Library. STUDY SELECTION: Studies eligible for inclusion were randomized controlled and observational studies on the relative clinical effect of amiodarone or lidocaine in cardiac arrest...
February 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28060157/posttraumatic-seizures-in-children-with-severe-traumatic-brain-injury
#11
John Kuluz
No abstract text is available yet for this article.
January 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27803144/pediatric-hydrocephalus-current-state-of-diagnosis-and-treatment
#12
Zachary Wright, Thomas W Larrew, Ramin Eskandari
No abstract text is available yet for this article.
November 2016: Pediatrics in Review
https://www.readbyqxmd.com/read/27803143/stroke-in-neonates-and-children
#13
Miya E Bernson-Leung, Michael J Rivkin
No abstract text is available yet for this article.
November 2016: Pediatrics in Review
https://www.readbyqxmd.com/read/28121832/central-venous-to-arterial-co2-difference-after-cardiac-surgery-in-infants-and-neonates
#14
Leslie A Rhodes, W Clinton Erwin, Santiago Borasino, David C Cleveland, Jeffrey A Alten
OBJECTIVES: Venous to arterial CO2 difference correlates with cardiac output in critically ill adults, but its utility in pediatric patients is unclear. We sought to correlate venous to arterial CO2 difference with other cardiac output surrogates (arteriovenous oxygen saturation difference, central venous oxygen saturation, and lactate) and investigate its capacity to predict poor outcomes associated with low cardiac output (low cardiac output syndrome) in infants after cardiac surgery with cardiopulmonary bypass...
January 24, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28121833/volume-targeted-ventilation-in-the-neonate-benchmarking-ventilators-on-an-active-lung-model
#15
Tobias J Krieger, Martin Wald
OBJECTIVE: Mechanically ventilated neonates have been observed to receive substantially different ventilation after switching ventilator models, despite identical ventilator settings. This study aims at establishing the range of output variability among 10 neonatal ventilators under various breathing conditions. DESIGN: Relative benchmarking test of 10 neonatal ventilators on an active neonatal lung model. SETTING: Neonatal ICU. SUBJECTS: Ten current neonatal ventilators...
January 24, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28108756/left-ventricular-noncompaction-cardiomyopathy-in-pediatric-patients-a-case-series-of-a-clinically-heterogeneous-disease
#16
Umang Gupta, Pooja Makhija
Left ventricular noncompaction is a rare form of cardiomyopathy, which results from multiple trabeculations in the left ventricular myocardium. The clinical presentation is highly variable, and spectrum includes asymptomatic patients diagnosed during family screening on one end to patients with depressed systolic function, heart failure, thromboembolic complications, and cardiac arrhythmias on the other (Kim et al in J Am Coll Cardiol 53: 2009, 2009). Further, the progression of the condition is highly variable...
January 21, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28142140/dha-reduces-oxidative-stress-after-perinatal-asphyxia-a-study-in-newborn-piglets
#17
Rønnaug Solberg, Mariangela Longini, Fabrizio Proietti, Serafina Perrone, Cosetta Felici, Alessio Porta, Ola Didrik Saugstad, Giuseppe Buonocore
BACKGROUND: Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurological morbidity in infants and children. Oxidative stress due to free radical formation and the initiation of abnormal oxidative reactions appears to play a key role. Docosahexanoic acid (DHA), a main component of brain membrane phospholipids, may act as a neuroprotectant after hypoxia-ischemia by regulating multiple molecular pathways and gene expression. OBJECTIVES: The aims of this study were to test the hypothesis that DHA provides significant protection against lipoperoxidation damage in the cerebral cortex and hippocampus in a neonatal piglet model of severe hypoxia-reoxygenation...
February 1, 2017: Neonatology
https://www.readbyqxmd.com/read/28137353/management-of-neonatal-hypotension
#18
Brian T Kalish
Hypotension is a common problem in neonates with complex underlying pathophysiology. Although treatment of low blood pressure is common, clinicians must use all available information to target neonates with compromised perfusion. Pharmacotherapy should be tailored to the specific physiologic perturbations of the individual neonate. Dopamine is the most commonly utilized agent and may be the most appropriate agent for septic shock with low diastolic blood pressure. However, alternative therapies should be considered for other etiologies of hypotension, including milrinone and vasopressin for persistent pulmonary hypertension of the newborn and dobutamine for patent ductus arteriosus...
January 1, 2017: Neonatal Network: NN
https://www.readbyqxmd.com/read/28137355/preeclampsia-and-care-of-the-newborn
#19
Julie Cardona, Mary Lou Simoncelli, Courtney Sexton, Deborah A Raines
Preeclampsia is one of the most common complications in the last half of pregnancy. Mother-baby nurses are often present at the birth to provide neonatal care as well as ongoing care during the first days of life. This article discusses the implications of preeclampsia for the neonate and the role of the mother-baby nurse in the care of these infants.
January 1, 2017: Neonatal Network: NN
https://www.readbyqxmd.com/read/28108103/respiratory-support-for-very-low-birth-weight-infants-receiving-dexamethasone
#20
Yamini V Virkud, Christoph P Hornik, Daniel K Benjamin, Matthew M Laughon, Reese H Clark, Rachel G Greenberg, P Brian Smith
OBJECTIVE: To assess how neonatal intensive care units followed the American Academy of Pediatrics guidelines for use of dexamethasone in preterm infants by evaluating respiratory support at the time of dexamethasone administration. STUDY DESIGN: This is an observational study of infants discharged from one of 290 neonatal intensive care units from 2003 to 2010. The cohort included very low birth weight (<1500 g birth weight) infants born at ≤32 weeks gestational age...
January 18, 2017: Journal of Pediatrics
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