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By César Gerardo Martínez Hernández General and Nuclear Cardiologist
https://www.readbyqxmd.com/read/28944172/surgical-treatment-for-hypertrophic-cardiomyopathy-a-historical-perspective
#1
REVIEW
Dustin Hang, Anita Nguyen, Hartzell V Schaff
Our understanding of hypertrophic cardiomyopathy (HCM) as a disease entity has increased dramatically over the last half century. There has been a concerted effort by several surgical groups to develop operative techniques to relieve left ventricular outflow tract (LVOT) obstruction and alleviate symptoms. This paper traces the development of transaortic septal myectomy, the current gold standard therapy for relief of LVOT obstruction, in symptomatic patients refractory to medical treatment. In addition, we introduce newer methods for myectomy that have expanded the role of surgery in patients with various forms of HCM...
July 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29114008/2017-american-heart-association-focused-update-on-adult-basic-life-support-and-cardiopulmonary-resuscitation-quality-an-update-to-the-american-heart-association-guidelines-for-cardio-pulmonary-resuscitation-and-emergency-cardiovascular-care
#2
REVIEW
Monica E Kleinman, Zachary D Goldberger, Thomas Rea, Robert A Swor, Bentley J Bobrow, Erin E Brennan, Mark Terry, Robin Hemphill, Raúl J Gazmuri, Mary Fran Hazinski, Andrew H Travers
Cardiopulmonary resuscitation is a lifesaving technique for victims of sudden cardiac arrest. Despite advances in resuscitation science, basic life support remains a critical factor in determining outcomes. The American Heart Association recommendations for adult basic life support incorporate the most recently published evidence and serve as the basis for education and training for laypeople and healthcare providers who perform cardiopulmonary resuscitation.
November 6, 2017: Circulation
https://www.readbyqxmd.com/read/29114010/2017-international-consensus-on-cardiopulmonary-resuscitation-and-emergency-cardiovascular-care-science-with-treatment-recommendations-summary
#3
REVIEW
Theresa M Olasveengen, Allan R de Caen, Mary E Mancini, Ian K Maconochie, Richard Aickin, Dianne L Atkins, Robert A Berg, Robert M Bingham, Steven C Brooks, Maaret Castrén, Sung Phil Chung, Julie Considine, Thomaz Bittencourt Couto, Raffo Escalante, Raúl J Gazmuri, Anne-Marie Guerguerian, Tetsuo Hatanaka, Rudolph W Koster, Peter J Kudenchuk, Eddy Lang, Swee Han Lim, Bo Løfgren, Peter A Meaney, William H Montgomery, Peter T Morley, Laurie J Morrison, Kevin J Nation, Kee-Chong Ng, Vinay M Nadkarni, Chika Nishiyama, Gabrielle Nuthall, Gene Yong-Kwang Ong, Gavin D Perkins, Amelia G Reis, Giuseppe Ristagno, Tetsuyo Sakamoto, Michael R Sayre, Stephen M Schexnayder, Alfredo F Sierra, Eunice M Singletary, Naoki Shimizu, Michael A Smyth, David Stanton, Janice A Tijssen, Andrew Travers, Christian Vaillancourt, Patrick Van de Voorde, Mary Fran Hazinski, Jerry P Nolan
The International Liaison Committee on Resuscitation has initiated a near-continuous review of cardiopulmonary resuscitation science that replaces the previous 5-year cyclic batch-and-queue approach process. This is the first of an annual series of International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations summary articles that will include the cardiopulmonary resuscitation science reviewed by the International Liaison Committee on Resuscitation in the previous year...
November 6, 2017: Circulation
https://www.readbyqxmd.com/read/29084738/international-expert-consensus-on-switching-platelet-p2y12-receptor-inhibiting-therapies
#4
REVIEW
Dominick J Angiolillo, Fabiana Rollini, Robert F Storey, Deepak L Bhatt, Stefan James, David J Schneider, Dirk Sibbing, Derek Y F So, Dietmar Trenk, Dimitrios Alexopoulos, Paul A Gurbel, Willibald Hochholzer, Leonardo De Luca, Laurent Bonello, Daniel Aradi, Thomas Cuisset, Udaya S Tantry, Tracy Y Wang, Marco Valgimigli, Ron Waksman, Roxana Mehran, Gilles Montalescot, Francesco Franchi, Matthew J Price
Dual antiplatelet therapy with aspirin and a P2Y12 inhibitor is the treatment of choice for the prevention of atherothrombotic events in patients with acute coronary syndromes and for those undergoing percutaneous coronary interventions. The availability of different oral P2Y12 inhibitors (clopidogrel, prasugrel, ticagrelor) has enabled physicians to contemplate switching among therapies because of specific clinical scenarios. The recent introduction of an intravenous P2Y12 inhibitor (cangrelor) further adds to the multitude of modalities and settings in which switching therapies may occur...
November 14, 2017: Circulation
https://www.readbyqxmd.com/read/29050566/how-low-to-go-with-glucose-cholesterol-%C3%A2-and-blood-pressure-in-primary%C3%A2-prevention-of-cvd
#5
REVIEW
Kimberly N Hong, Valentin Fuster, Robert S Rosenson, Clive Rosendorff, Deepak L Bhatt
Diabetes, hyperlipidemia, and hypertension are modifiable risk factors that predict cardiovascular disease events. The effect of these risk factors on incident cardiovascular disease increases with progressively higher levels of glucose, low-density lipoprotein cholesterol, and blood pressure. The thresholds for initiating treatment of these modifiable risk factors and the optimal goals of risk factor modification are a focus of primary prevention research. Although an aggressive approach is appealing, adverse events may occur, and potential physiological barriers may exist...
October 24, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29084733/2017-aha-acc-hrs-guideline-for-management-of-patients-with-ventricular-arrhythmias-and-the-prevention-of-sudden-cardiac-death-executive-summary-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines
#6
REVIEW
Sana M Al-Khatib, William G Stevenson, Michael J Ackerman, William J Bryant, David J Callans, Anne B Curtis, Barbara J Deal, Timm Dickfeld, Michael E Field, Gregg C Fonarow, Anne M Gillis, Mark A Hlatky, Christopher B Granger, Stephen C Hammill, José A Joglar, G Neal Kay, Daniel D Matlock, Robert J Myerburg, Richard L Page
No abstract text is available yet for this article.
October 30, 2017: Circulation
https://www.readbyqxmd.com/read/29097296/2017-aha-acc-hrs-guideline-for-management-of-patients-with-ventricular-arrhythmias-and-the-prevention-of-sudden-cardiac-death-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice-guidelines-and-the-heart
#7
Sana M Al-Khatib, William G Stevenson, Michael J Ackerman, William J Bryant, David J Callans, Anne B Curtis, Barbara J Deal, Timm Dickfeld, Michael E Field, Gregg C Fonarow, Anne M Gillis, Mark A Hlatky, Christopher B Granger, Stephen C Hammill, José A Joglar, G Neal Kay, Daniel D Matlock, Robert J Myerburg, Richard L Page
No abstract text is available yet for this article.
October 25, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29097297/systematic-review-for-the-2017-aha-acc-hrs-guideline-for-management-of-patients-with-ventricular-arrhythmias-and-the-prevention-of-sudden-cardiac-death-a-report-of-the-american-college-of-cardiology-american-heart-association-task-force-on-clinical-practice
#8
Fred M Kusumoto, Kent R Bailey, Ahmad Sami Chaouki, Abhishek J Deshmukh, Sandeep Gautam, Robert J Kim, Daniel B Kramer, Litsa K Lambrakos, Naseer H Nasser, Dan Sorajja
BACKGROUND: Although large randomized clinical trials have found that primary prevention use of an implantable cardioverter-defibrillator (ICD) improves survival in patients with cardiomyopathy and heart failure symptoms, patients who receive ICDs in practice are often older and have more comorbidities than patients who were enrolled in the clinical trials. In addition, there is a debate among clinicians on the usefulness of electrophysiological study for risk stratification of asymptomatic patients with Brugada syndrome...
October 24, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28824788/peripheral-interventions-and-antiplatelet-therapy-role-in-current-practice
#9
REVIEW
Pahul Singh, Yenal Harper, Carrie S Oliphant, Mohamed Morsy, Michelle Skelton, Raza Askari, Rami N Khouzam
Peripheral arterial disease (PAD) is a common disorder associated with a high risk of cardiovascular mortality and continues to be under-recognized. The major risk factors for PAD are similar to those for coronary and cerebrovascular disease. Management includes exercise program, pharmacologic therapy and revascularization including endovascular and surgical approach. The optimal revascularization strategy, endovascular or surgical intervention, is often debated due to the paucity of head to head randomized controlled studies...
July 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/29083953/pci-strategies-in-patients-with-acute-myocardial-infarction-and-cardiogenic-shock
#10
Holger Thiele, Ibrahim Akin, Marcus Sandri, Georg Fuernau, Suzanne de Waha, Roza Meyer-Saraei, Peter Nordbeck, Tobias Geisler, Ulf Landmesser, Carsten Skurk, Andreas Fach, Harald Lapp, Jan J Piek, Marko Noc, Tomaž Goslar, Stephan B Felix, Lars S Maier, Janina Stepinska, Keith Oldroyd, Pranas Serpytis, Gilles Montalescot, Olivier Barthelemy, Kurt Huber, Stephan Windecker, Stefano Savonitto, Patrizia Torremante, Christiaan Vrints, Steffen Schneider, Steffen Desch, Uwe Zeymer
Background In patients who have acute myocardial infarction with cardiogenic shock, early revascularization of the culprit artery by means of percutaneous coronary intervention (PCI) improves outcomes. However, the majority of patients with cardiogenic shock have multivessel disease, and whether PCI should be performed immediately for stenoses in nonculprit arteries is controversial. Methods In this multicenter trial, we randomly assigned 706 patients who had multivessel disease, acute myocardial infarction, and cardiogenic shock to one of two initial revascularization strategies: either PCI of the culprit lesion only, with the option of staged revascularization of nonculprit lesions, or immediate multivessel PCI...
October 30, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28992817/clinical-recommendations-for-cardiovascular-magnetic-resonance-mapping-of-t1-t2-t2-and-extracellular-volume-a-consensus-statement-by-the-society-for-cardiovascular-magnetic-resonance-scmr-endorsed-by-the-european-association-for-cardiovascular-imaging-eacvi
#11
REVIEW
Daniel R Messroghli, James C Moon, Vanessa M Ferreira, Lars Grosse-Wortmann, Taigang He, Peter Kellman, Julia Mascherbauer, Reza Nezafat, Michael Salerno, Erik B Schelbert, Andrew J Taylor, Richard Thompson, Martin Ugander, Ruud B van Heeswijk, Matthias G Friedrich
Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR). Parametric mapping with CMR now permits the routine spatial visualization and quantification of changes in myocardial composition based on changes in T1, T2, and T2*(star) relaxation times and extracellular volume (ECV). These changes include specific disease pathways related to mainly intracellular disturbances of the cardiomyocyte (e...
October 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29066452/inflammatory-biomarkers-interleukin-6-and-c-reactive-protein-and-outcomes-in-stable-coronary-heart-disease-experiences-from-the-stability-stabilization-of-atherosclerotic-plaque-by-initiation-of-darapladib-therapy-trial
#12
Claes Held, Harvey D White, Ralph A H Stewart, Andrzej Budaj, Christopher P Cannon, Judith S Hochman, Wolfgang Koenig, Agneta Siegbahn, Philippe Gabriel Steg, Joseph Soffer, W Douglas Weaver, Ollie Östlund, Lars Wallentin
BACKGROUND: Evaluation of cardiovascular prognosis in patients with stable coronary heart disease is based on clinical characteristics and biomarkers indicating dysglycemia, dyslipidemia, renal dysfunction, and possibly cardiac dysfunction. Inflammation plays a key role in atherosclerosis, but the association between inflammatory biomarkers and clinical outcomes is less studied in this population. METHODS AND RESULTS: Overall, 15 828 patients with coronary heart disease in the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) trial were randomized to treatment with darapladib or placebo and observed for a median of 3...
October 24, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29033611/stable-ischemic-heart-disease-in-women-current-perspectives
#13
REVIEW
Fatima Samad, Anushree Agarwal, Zainab Samad
Cardiovascular disease is the leading cause of death in women accounting for 1 in every 4 female deaths. Pathophysiology of ischemic heart disease in women includes epicardial coronary artery, endothelial dysfunction, coronary vasospasm, plaque erosion and spontaneous coronary artery dissection. Angina is the most common presentation of stable ischemic heart disease (SIHD) in women. Risk factors for SIHD include traditional risks such as older age, obesity (body mass index [BMI] >25 kg/m(2)), smoking, hypertension, dyslipidemia, cerebrovascular and peripheral vascular disease, sedentary lifestyle, family history of premature coronary artery disease, metabolic syndrome and diabetes mellitus, and nontraditional risk factors, such as gestational diabetes, insulin resistance/polycystic ovarian disease, pregnancy-induced hypertension, pre-eclampsia, eclampsia, menopause, mental stress and autoimmune diseases...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29016754/cardiac-troponins-from-myocardial-infarction-to-chronic-disease
#14
Kyung Chan Park, David C Gaze, Paul O Collinson, Michael S Marber
Elucidation of the physiologically distinct subunits of troponin in 1973 greatly facilitated our understanding of cardiac contraction. Although troponins are expressed in both skeletal and cardiac muscle, there are isoforms of troponin I/T expressed selectively in the heart. By exploiting cardiac-restricted epitopes within these proteins, one of the most successful diagnostic tests to-date has been developed: cardiac troponin (cTn) assays. For the past decade, cTn has been regarded as the gold-standard marker for acute myocardial necrosis: the pathological hallmark of acute myocardial infarction (AMI)...
September 14, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/29029100/2017-eacts-eacta-guidelines-on-patient-blood-management-for-adult-cardiac-surgery-the-task-force-on-patient-blood-management-for-adult-cardiac-surgery-of-the-european-association-for-cardio-thoracic-surgery-eacts-and-the-european-association-of-cardiothoracic
#15
Domenico Pagano, Milan Milojevic, Michael I Meesters, Umberto Benedetto, Daniel Bolliger, Christian von Heymann, Anders Jeppsson, Andreas Koster, Ruben L Osnabrugge, Marco Ranucci, Hanne Berg Ravn, Alexander B A Vonk, Alexander Wahba, Christa Boer, Moritz W V Wyler von Ballmoos, Mate Petricevic, Arie Pieter Kappetein, Miguel Sousa-Uva, Georg Trummer, Peter M Rosseel, Michael Sander, Pascal Colson, Adrian Bauer
No abstract text is available yet for this article.
October 3, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029110/2017-eacts-guidelines-on-perioperative-medication-in-adult-cardiac-surgery
#16
Miguel Sousa-Uva, Stuart J Head, Milan Milojevic, Jean-Philippe Collet, Giovanni Landoni, Manuel Castella, Joel Dunning, Tómas Gudbjartsson, Nick J Linker, Elena Sandoval, Matthias Thielmann, Anders Jeppsson, Ulf Landmesser
No abstract text is available yet for this article.
October 6, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29054308/acc-aats-aha-ase-eacts-hvs-sca-scai-scct-scmr-sts-2017-appropriate-use-criteria-for-the-treatment-of-patients-with-severe-aortic-stenosis-a-report-of-the-american-college-of-cardiology-appropriate-use-criteria-task-force-american-association-for-thoracic-surgery
#17
https://www.readbyqxmd.com/read/28900614/echocardiographic-evaluation-of-pulmonary-pressures-and-right-ventricular-function-after-pediatric-cardiac-surgery-a-simple-approach-for-the-intensivist
#18
REVIEW
Maurice Beghetti
Pulmonary hypertension (PH) is diagnosed using cardiac catheterization and is defined as an elevation of mean pulmonary artery pressure (PAP) greater than 25 mmHg. Although invasive hemodynamics remains the gold standard and is mandatory for disease confirmation, transthoracic echocardiography (TTE) is an extremely useful non-invasive and widely available tool that allows for screening and follow-up, in particular, in the acute setting. TTE may be a valuable alternative, allowing for direct measurement and/or indirect assessment of PAP...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29030424/stable-coronary-syndromes-pathophysiology-diagnostic-advances-and-therapeutic-need
#19
REVIEW
Thomas J Ford, David Corcoran, Colin Berry
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation. This clinical paradigm fails to account for the considerable proportion (approximately one-third) of patients with angina in whom obstructive CAD is excluded. This common scenario presents a diagnostic conundrum whereby angina occurs but there is no obstructive CAD (ischaemia and no obstructive coronary artery disease-INOCA)...
October 13, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28982370/effect-of-angiotensin-converting-enzyme-inhibitors-and-angiotensin-ii-receptor-blockers-on-cardiovascular-events-in-patients-with-heart-failure-a-meta-analysis-of-randomized-controlled-trials
#20
Chenhui Tai, Tianyi Gan, Liling Zou, Yuxi Sun, Yi Zhang, Wei Chen, Jue Li, Jian Zhang, Yawei Xu, Huihe Lu, Dachun Xu
BACKGROUND: Heart failure (HF) remains a significant cause of morbidity and mortality. Multiple trials over the past several years have examined the effects of both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) in the treatment of left ventricular dysfunction, both acutely after myocardial infarction and in chronic heart failure. Yet, there is still confusion regarding the relative efficacy of rennin-angiotensin-aldosterone system (RAAS) inhibition...
October 5, 2017: BMC Cardiovascular Disorders
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