Morgan E Grams, Nigel J Brunskill, Shoshana H Ballew, Yingying Sang, Josef Coresh, Kunihiro Matsushita, Aditya Surapaneni, Samira Bell, Juan J Carrero, Gabriel Chodick, Marie Evans, Hiddo J L Heerspink, Lesley A Inker, Kunitoshi Iseki, Philip A Kalra, H Lester Kirchner, Brian J Lee, Adeera Levin, Rupert W Major, James Medcalf, Girish N Nadkarni, David M J Naimark, Ana C Ricardo, Simon Sawhney, Manish M Sood, Natalie Staplin, Nikita Stempniewicz, Benedicte Stengel, Keiichi Sumida, Jamie P Traynor, Jan van den Brand, Chi-Pang Wen, Mark Woodward, Jae Won Yang, Angela Yee-Moon Wang, Navdeep Tangri
SIGNIFICANCE STATEMENT: The kidney failure risk equation (KFRE) uses age, sex, GFR, and urine albumin-to-creatinine ratio (ACR) to predict 2- and 5-year risk of kidney failure in populations with eGFR <60 ml/min per 1.73 m 2 . However, the CKD-EPI 2021 creatinine equation for eGFR is now recommended for use but has not been fully tested in the context of KFRE. In 59 cohorts comprising 312,424 patients with CKD, the authors assessed the predictive performance and calibration associated with the use of the CKD-EPI 2021 equation and whether additional variables and accounting for the competing risk of death improves the KFRE's performance...
March 1, 2023: Journal of the American Society of Nephrology: JASN