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Placebo effect

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Uri Nitzan, Yossi Chalamish, Israel Krieger, Hany Burstein Erez, Yoram Braw, Pesach Lichtenberg
BACKGROUND: The growing awareness that so many do not respond adequately to antidepressant (AD) pharmacotherapy has sparked research seeking to characterize those who do. While the pharmacological mechanisms of AD treatment have been extensively evaluated, much remains unknown about the placebo component of the response to medication. This study examined the association between suggestibility levels and response to ADs amongst depressed patients. METHODS: Twenty unipolar depression outpatients, recruited before starting AD monotherapy, received clear, standardized instructions that the therapeutic effects of AD, though not side effects, would require 2-4 weeks...
October 1, 2015: Journal of Affective Disorders
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