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185 papers 25 to 100 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
Salam Abbara, Aurélia Pitsch, Sébastien Jochmans, Kyann Hodjat, Dr Pascale Cherrier, Mehran Monchi, Christophe Vinsonneau, Sylvain Diamantis
OBJECTIVES: To assess if the postprescription review and feedback (PPRF) of all antibiotics with restriction of carbapenems, fluoroquinolones and third generation cephalosporins, along with a change of medical standard of care, impacted the consumption of antibiotics and bacterial resistance in a medical/surgical intensive care unit (MSICU). METHODS: A four years before (2007-2010) and after (2011-2014) retrospective comparative study. Antibiotics consumption was evaluated in Defined Daily Doses per 1000 patient days...
December 8, 2018: International Journal of Antimicrobial Agents
Nicole Quah Qin Xian, Wan Wei Ang, Shanxi A Jen
No abstract text is available yet for this article.
December 1, 2018: JAMA Internal Medicine
Ramesh Venkatapathy, Vasupradha Govindarajan, Nirima Oza, Sreejith Parameswaran, Balamurali Pennagaram Dhanasekaran, Karthikshree V Prashad
Context. Sampling blood for serum analysis is an invasive procedure. A noninvasive alternative would be beneficial to patients and health care professionals. Aim. To correlate serum and salivary creatinine levels and evaluate the role of saliva as a noninvasive alternative to serum for creatinine estimation in chronic kidney disease patients. Study Design. Case-control study. Methods. Blood and saliva samples were collected from 37 healthy individuals and 105 chronic kidney disease patients. Serum and salivary creatinine levels were estimated using automatic analyser...
2014: International Journal of Nephrology
Matthew L Goldman, Carol A Bernstein, Richard F Summers
No abstract text is available yet for this article.
November 30, 2018: JAMA: the Journal of the American Medical Association
Peter J Blankestijn, Annette Bruchfeld, Giovambattista Capasso, Danilo Fliser, Denis Fouque, Dimitrios Goumenos, Ziad Massy, Ivan Rychlík, Maria José Soler, Goce Spasovski, Kate Stevens, Christoph Wanner, Carmine Zoccali
No abstract text is available yet for this article.
November 29, 2018: Nephrology, Dialysis, Transplantation
Leonard G Feld, Daniel R Neuspiel, Byron A Foster, Michael G Leu, Matthew D Garber, Kelly Austin, Rajit K Basu, Edward E Conway, James J Fehr, Clare Hawkins, Ron L Kaplan, Echo V Rowe, Muhammad Waseem, Michael L Moritz
Maintenance intravenous fluids (IVFs) are used to provide critical supportive care for children who are acutely ill. IVFs are required if sufficient fluids cannot be provided by using enteral administration for reasons such as gastrointestinal illness, respiratory compromise, neurologic impairment, a perioperative state, or being moribund from an acute or chronic illness. Despite the common use of maintenance IVFs, there is high variability in fluid prescribing practices and a lack of guidelines for fluid composition administration and electrolyte monitoring...
November 26, 2018: Pediatrics
Jasmeet Soar, Michael W Donnino, Ian Maconochie, Richard Aickin, Dianne L Atkins, Lars W Andersen, Katherine M Berg, Robert Bingham, Bernd W Böttiger, Clifton W Callaway, Keith Couper, Thomaz Bittencourt Couto, Allan R de Caen, Charles D Deakin, Ian R Drennan, Anne-Marie Guerguerian, Eric J Lavonas, Peter A Meaney, Vinay M Nadkarni, Robert W Neumar, Kee-Chong Ng, Tonia C Nicholson, Gabrielle A Nuthall, Shinichiro Ohshimo, Brian J O'Neil, Gene Yong-Kwang Ong, Edison F Paiva, Michael J Parr, Amelia G Reis, Joshua C Reynolds, Giuseppe Ristagno, Claudio Sandroni, Stephen M Schexnayder, Barnaby R Scholefield, Naoki Shimizu, Janice A Tijssen, Patrick Van de Voorde, Tzong-Luen Wang, Michelle Welsford, Mary Fran Hazinski, Jerry P Nolan, Peter T Morley
The International Liaison Committee on Resuscitation has initiated a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation science. This is the second annual summary of International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations that includes the most recent cardiopulmonary resuscitation science reviewed by the International Liaison Committee on Resuscitation. This summary addresses the role of antiarrhythmic drugs in adults and children and includes the Advanced Life Support Task Force and Pediatric Task Force consensus statements, which summarize the most recent published evidence and an assessment of the quality of the evidence based on Grading of Recommendations, Assessment, Development, and Evaluation criteria...
December 2018: Resuscitation
Chris Bonell, Elizabeth Allen, Emily Warren, Jennifer McGowan, Leonardo Bevilacqua, Farah Jamal, Rosa Legood, Meg Wiggins, Charles Opondo, Anne Mathiot, Jo Sturgess, Adam Fletcher, Zia Sadique, Diana Elbourne, Deborah Christie, Lyndal Bond, Stephen Scott, Russell M Viner
BACKGROUND: Bullying, aggression, and violence among children and young people are some of the most consequential public mental health problems. We tested the Learning Together intervention, which involved students in efforts to modify their school environment using restorative practice and by developing social and emotional skills. METHODS: We did a cluster randomised trial, with economic and process evaluations, of the Learning Together intervention compared with standard practice (controls) over 3 years in secondary schools in south-east England...
November 22, 2018: Lancet
Tim M Reynolds, Anthony S Wierzbicki
BACKGROUND: Increasing demand for laboratory testing at weekends is common but little is known about its appropriateness. METHODS: An audit was conducted in a large district hospital of routine haematology and clinical biochemistry requests ordered over 2 weekends. Appropriateness was assessed by review of ordered tests compared with clinical records by a qualified chemical pathologist. RESULTS: Profiles requested on phlebotomy included full blood count (76%), renal profile (91%), C-Reactive protein (41%), liver function tests (18%) and another test in 18%...
November 25, 2018: International Journal of Clinical Practice
Robert Hatch, Duncan Young, Vicki Barber, John Griffiths, David A Harrison, Peter Watkinson
BACKGROUND: Survivors of intensive care are known to be at increased risk of developing longer-term psychopathology issues. We present a large UK multicentre study assessing the anxiety, depression and post-traumatic stress disorder (PTSD) caseness in the first year following discharge from an intensive care unit (ICU). METHODS: Design: prospective multicentre follow-up study of survivors of ICU in the UK. SETTING: patients from 26 ICUs in the UK...
November 23, 2018: Critical Care: the Official Journal of the Critical Care Forum
Darren Taichman, Sue S Bornstein, Christine Laine
No abstract text is available yet for this article.
November 20, 2018: Annals of Internal Medicine
Hakim Celik, Ufuk Duzenli, Mehmet Aslan, Ibrahim Halil Altiparmak, Adnan Kirmit, Erdal Kara, Ali Ziya Karakilcik
BACKGROUND: ABO blood groups have been suggested to have a high correlation with cardiovascular diseases (CVDs). It has also been postulated that platelet indices, including mean platelet volume (MPV) and platelet distribution width (PDW), are very important in the development and progression of CVDs. However, despite these common associations with CVDs, as far as we know, there are no studies investigating platelet indices in ABO blood groups. Thus, the aim of this study was to investigate whether platelet indices are associated with ABO blood groups...
November 21, 2018: Journal of Clinical Laboratory Analysis
Sayo Ueda, Taichi Murakami, Hirokazu Ogino, Motokazu Matsuura, Masanori Tamaki, Seiji Kishi, Mike Hann, Yuko Toyoda, Kojiro Nagai, Yoshimi Bando, Hideharu Abe, Yasuhiko Nishioka, Toshio Doi
A 61-year-old man was diagnosed with sarcoidosis involving the lungs, eyes, parotid gland and extrathoracic lymph nodes complicated by chronic kidney injury and hypercalcemia. Kidney biopsy showed non-specific interstitial nephritis and nephrosclerosis. However, immunohistochemical staining of cell surface markers revealed a multinucleated giant macrophage surrounded by T-cells, suggesting granulomatous interstitial nephritis. Corticosteroid improved the kidney function, and reduced the serum levels of calcium and angiotensin-converting enzyme...
November 19, 2018: Internal Medicine
Jeroen P Kooman, Len A Usvyat, Marijke J E Dekker, Dugan W Maddux, Jochen G Raimann, Frank M van der Sande, Xiaoling Ye, Yuedong Wang, Peter Kotanko
Patients with end-stage renal disease (ESRD) experience unique patterns in their lifetime, such as the start of dialysis and renal transplantation. In addition, there is also an intricate link between ESRD and biological time patterns. In terms of cyclic patterns, the circadian blood pressure (BP) rhythm can be flattened, contributing to allostatic load, whereas the circadian temperature rhythm is related to the decline in BP during hemodialysis (HD). Seasonal variations in BP and interdialytic-weight gain have been observed in ESRD patients in addition to a profound relative increase in mortality during the winter period...
November 16, 2018: Blood Purification
Wen-Ying Sylvia Chou, April Oh, William M P Klein
No abstract text is available yet for this article.
November 14, 2018: JAMA: the Journal of the American Medical Association
Renee Butkus, Robert Doherty, Sue S Bornstein
For more than 20 years, the American College of Physicians (ACP) has advocated for the need to address firearm-related injuries and deaths in the United States. Yet, firearm violence continues to be a public health crisis that requires the nation's immediate attention. The policy recommendations in this paper build on, strengthen, and expand current ACP policies approved by the Board of Regents in April 2014, based on analysis of approaches that the evidence suggests will be effective in reducing deaths and injuries from firearm-related violence...
November 20, 2018: Annals of Internal Medicine
Jason D Chodakowski, D Mark Courtney
PURPOSE OF REVIEW: We provide a timely update on treatment care issues facing clinicians and patients with acute pulmonary embolism accompanied by either right ventricular strain (sub-massive pulmonary embolism) or shock (massive pulmonary embolism). RECENT FINDINGS: Care and research changes over the last several years have resulted in four important trends: more consensus and accuracy in the way acute pulmonary embolism severity is described and communicated among acute care clinicians and researchers, increased availability and use of risk prediction scoring systems, increased use of advanced invasive therapy in the setting of severe right ventricular dysfunction, and emergence of multidisciplinary pulmonary embolism response teams to guide standard care decision-making...
December 2018: Current Opinion in Critical Care
Pawan Agrawal, Tirtha Man Shrestha, Pratap Narayan Prasad, Ramesh Prasad Aacharya, Priyanka Gupta
INTRODUCTION: In pleural effusion, differentiating exudative and transudative fluid is an important clinical evaluation. The objective of the study was to determine the efficacy of pleural fluid serum bilirubin ratio in differentiating exudative and transudative effusions. In resource-limited settings with no facilities to measure lactate dehydrogenase levels, using pleural fluid bilirubin ratio may help in better clinical decision. METHODS: It was a cross sectional study, conducted in the emergency department of Tribhuvan University Teaching Hospital...
March 2018: JNMA; Journal of the Nepal Medical Association
Timothy D Girard, Matthew C Exline, Shannon S Carson, Catherine L Hough, Peter Rock, Michelle N Gong, Ivor S Douglas, Atul Malhotra, Robert L Owens, Daniel J Feinstein, Babar Khan, Margaret A Pisani, Robert C Hyzy, Gregory A Schmidt, William D Schweickert, R Duncan Hite, David L Bowton, Andrew L Masica, Jennifer L Thompson, Rameela Chandrasekhar, Brenda T Pun, Cayce Strength, Leanne M Boehm, James C Jackson, Pratik P Pandharipande, Nathan E Brummel, Christopher G Hughes, Mayur B Patel, Joanna L Stollings, Gordon R Bernard, Robert S Dittus, E Wesley Ely
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive delirium to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. The volume and dose of a trial drug or placebo was halved or doubled at 12-hour intervals on the basis of the presence or absence of delirium, as detected with the use of the Confusion Assessment Method for the ICU, and of side effects of the intervention...
October 22, 2018: New England Journal of Medicine
Joseph J Shatzel, Matthew O'Donnell, Sven R Olson, Matthew R Kearney, Molly M Daughety, Justine Hum, Khanh P Nguyen, Thomas G DeLoughery
Thrombosis of unusual venous sites encompasses a large part of consultative hematology and is encountered routinely by practicing hematologists. Contrary to the more commonly encountered lower extremity venous thrombosis and common cardiovascular disorders, the various thromboses outlined in this review have unique presentations, pathophysiology, workup, and treatments that all hematologists should be aware of. This review attempts to outline the most up to date literature on cerebral, retinal, upper extremity, hepatic, portal, splenic, mesenteric, and renal vein thrombosis, focusing on the incidence, pathophysiology, provoking factors, and current recommended treatments for each type of unusual thrombosis to provide a useful and practical review for the hematologist...
September 28, 2018: European Journal of Haematology
2018-10-22 11:30:44
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