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Medicina Interna / internal Medicine

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3210 papers 1000+ followers Medicina Interna - Internal Medicine / E-Mail: andresflmd@gmail.com
By Andrés López, M.D. Médico/Physician - M.D.
https://www.readbyqxmd.com/read/29686441/rheumatic-fever-new-diagnostic-criteria
#1
REVIEW
Izabela Szczygielska, Elżbieta Hernik, Beata Kołodziejczyk, Agnieszka Gazda, Maria Maślińska, Piotr Gietka
Rheumatic fever (RF) is an autoimmune disease associated with group A β-hemolytic streptococcal infection, in the course of which the patient develops carditis, arthritis, chorea, subcutaneous nodules and erythema marginatum. Rheumatic fever diagnosis is based on the Jones criteria, developed in 1944, then revised twice by the American Heart Association (AHA), in 1992 and recently in 2015. The last revision of the Jones criteria consists mainly in the supplementation of the major criteria with echocardiographic examination, the introduction of a concept of subclinical carditis and the isolation of low, medium and high risk populations among the patients...
2018: Reumatologia
https://www.readbyqxmd.com/read/29222379/8-pharmacologic-approaches-to-glycemic-treatment-standards-of-medical-care-in-diabetes-2018
#2
REVIEW
(no author information available yet)
The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations, please refer to the Standards of Care Introduction Readers who wish to comment on the Standards of Care are invited to do so at professional...
January 2018: Diabetes Care
https://www.readbyqxmd.com/read/29466596/acute-respiratory-distress-syndrome-advances-in-diagnosis-and-treatment
#3
REVIEW
Eddy Fan, Daniel Brodie, Arthur S Slutsky
Importance: Acute respiratory distress syndrome (ARDS) is a life-threatening form of respiratory failure that affects approximately 200 000 patients each year in the United States, resulting in nearly 75 000 deaths annually. Globally, ARDS accounts for 10% of intensive care unit admissions, representing more than 3 million patients with ARDS annually. Objective: To review advances in diagnosis and treatment of ARDS over the last 5 years. Evidence Review: We searched MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews from 2012 to 2017 focusing on randomized clinical trials, meta-analyses, systematic reviews, and clinical practice guidelines...
February 20, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29509871/the-diagnosis-and-management-of-thyroid-nodules-a-review
#4
REVIEW
Cosimo Durante, Giorgio Grani, Livia Lamartina, Sebastiano Filetti, Susan J Mandel, David S Cooper
Importance: Thyroid nodules are common, being detected in up to 65% of the general population. This is likely due to the increased use of diagnostic imaging for purposes unrelated to the thyroid. Most thyroid nodules are benign, clinically insignificant, and safely managed with a surveillance program. The main goal of initial and long-term follow-up is identification of the small subgroup of nodules that harbor a clinically significant cancer (≈10%), cause compressive symptoms (≈5%), or progress to functional disease (≈5%)...
March 6, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29614180/skin-abscess
#5
Ioana Baiu, Elliot Melendez
No abstract text is available yet for this article.
April 3, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29715342/management-of-dyspepsia
#6
Lauren Feld, Adam S Cifu
No abstract text is available yet for this article.
May 1, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29452711/primary-sclerosing-cholangitis
#7
REVIEW
Jessica K Dyson, Ulrich Beuers, David E J Jones, Ansgar W Lohse, Mark Hudson
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and fibrosis of bile ducts and the liver are followed by impaired bile formation or flow and progressive liver dysfunction. Patients might be asymptomatic at presentation or might have pruritus, fatigue, right upper quadrant pain, recurrent cholangitis, or sequelae of portal hypertension. The key diagnostic elements are cholestatic liver biochemistry and bile duct stricturing on cholangiography...
February 13, 2018: Lancet
https://www.readbyqxmd.com/read/29477250/chronic-lymphocytic-leukaemia
#8
REVIEW
Michael Hallek, Tait D Shanafelt, Barbara Eichhorst
Important advances in understanding the pathogenesis of chronic lymphocytic leukaemia in the past two decades have led to the development of new prognostic tools and novel targeted therapies that have improved clinical outcome. Chronic lymphocytic leukaemia is the most common type of leukaemia in developed countries, and the median age at diagnosis is 72 years. The criteria for initiating treatment rely on the Rai and Binet staging systems and on the presence of disease-related symptoms. For many patients with chronic lymphocytic leukaemia, treatment with chemotherapy and anti-CD20 monoclonal antibodies is the standard of care...
April 14, 2018: Lancet
https://www.readbyqxmd.com/read/29523342/migraine
#9
REVIEW
David W Dodick
Migraine is a chronic paroxysmal neurological disorder characterised by multiphase attacks of head pain and a myriad of neurological symptoms. The underlying genetic and biological underpinnings and neural networks involved are coming sharply into focus. This progress in the fundamental understanding of migraine has led to novel, mechanism-based and disease-specific therapeutics. In this Seminar, the clinical features and neurobiology of migraine are reviewed, evidence to support available treatment options is provided, and emerging drug, device, and biological therapies are discussed...
March 31, 2018: Lancet
https://www.readbyqxmd.com/read/29576504/multiple-sclerosis
#10
REVIEW
Alan J Thompson, Sergio E Baranzini, Jeroen Geurts, Bernhard Hemmer, Olga Ciccarelli
Multiple sclerosis continues to be a challenging and disabling condition but there is now greater understanding of the underlying genetic and environmental factors that drive the condition, including low vitamin D levels, cigarette smoking, and obesity. Early and accurate diagnosis is crucial and is supported by diagnostic criteria, incorporating imaging and spinal fluid abnormalities for those presenting with a clinically isolated syndrome. Importantly, there is an extensive therapeutic armamentarium, both oral and by infusion, for those with the relapsing remitting form of the disease...
April 21, 2018: Lancet
https://www.readbyqxmd.com/read/29631781/malaria
#11
REVIEW
Elizabeth A Ashley, Aung Pyae Phyo, Charles J Woodrow
Following unsuccessful eradication attempts there was a resurgence of malaria towards the end of the 20th century. Renewed control efforts using a range of improved tools, such as long-lasting insecticide-treated bednets and artemisinin-based combination therapies, have more than halved the global burden of disease, but it remains high with 445 000 deaths and more than 200 million cases in 2016. Pitfalls in individual patient management are delayed diagnosis and overzealous fluid resuscitation in severe malaria...
April 6, 2018: Lancet
https://www.readbyqxmd.com/read/29539283/hiv-associated-cancers-and-related-diseases
#12
REVIEW
Robert Yarchoan, Thomas S Uldrick
No abstract text is available yet for this article.
March 15, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29562162/autoimmune-polyendocrine-syndromes
#13
REVIEW
Eystein S Husebye, Mark S Anderson, Olle Kämpe
No abstract text is available yet for this article.
March 22, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29641969/diagnostic-use-of-base-excess-in-acid-base-disorders
#14
REVIEW
Kenrick Berend
New England Journal of Medicine, Volume 378, Issue 15, Page 1419-1428, April 2018.
April 12, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29540357/pulmonary-arterial-hypertension-pathogenesis-and-clinical-management
#15
REVIEW
Thenappan Thenappan, Mark L Ormiston, John J Ryan, Stephen L Archer
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of pulmonary hypertension that primarily affects the pulmonary vasculature. In PAH, the pulmonary vasculature is dynamically obstructed by vasoconstriction, structurally obstructed by adverse vascular remodeling, and pathologically non-compliant as a result of vascular fibrosis and stiffening. Many cell types are abnormal in PAH, including vascular cells (endothelial cells, smooth muscle cells, and fibroblasts) and inflammatory cells...
March 14, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29545242/bradyarrhythmias-and-pacemakers
#16
REVIEW
S Honarbakhsh, L Hunter, A Chow, Ross J Hunter
No abstract text is available yet for this article.
March 15, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29572251/managing-dyslipidaemia-for-the-primary-prevention-of-cardiovascular-disease
#17
REVIEW
Aidan Ryan, Simon Heath, Paul Cook
No abstract text is available yet for this article.
March 23, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29297007/comparison-shopping-guidelines-for-statins-for-primary-prevention-of-cardiovascular-disease
#18
G B John Mancini
No abstract text is available yet for this article.
January 16, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29310137/diagnosis-of-venous-thromboembolism-20-years-of-progress
#19
Philip S Wells, Ryma Ihaddadene, Aoife Reilly, Melissa Anne Forgie
Many guidelines suggest incorporating clinical assessment, imaging, and D-dimer testing into diagnostic algorithms in patients with suspected deep venous thrombosis (DVT) and pulmonary embolism (PE). This special article reviews the evidence supporting the use of algorithms and their individual components for diagnosis of upper- and lower-extremity DVT and PE in adults, including pregnant women. The authors identified evidence through several electronic database searches to April 2017, evaluated the robustness of selected evidence, assessed whether diagnostic approaches that do not use algorithms are acceptable, and identified knowledge gaps that require further research...
January 16, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29357392/prevention-detection-evaluation-and-management-of-high-blood-pressure-in-adults-synopsis-of-the-2017-american-college-of-cardiology-american-heart-association-hypertension-guideline
#20
Robert M Carey, Paul K Whelton
Description: In November 2017, the American College of Cardiology (ACC) and the American Heart Association (AHA) released a clinical practice guideline for the prevention, detection, evaluation, and treatment of high blood pressure (BP) in adults. This article summarizes the major recommendations. Methods: In 2014, the ACC and the AHA appointed a multidisciplinary committee to update previous reports of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure...
March 6, 2018: Annals of Internal Medicine
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