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ED Pharm

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6 papers 0 to 25 followers Literature pertinent to medication use in the ED.
By Merlin Curry MD, EMT-P
https://www.readbyqxmd.com/read/27176727/prehospital-administration-of-tranexamic-acid-in-trauma-patients
#1
Arasch Wafaisade, Rolf Lefering, Bertil Bouillon, Andreas B Böhmer, Michael Gäßler, Matthias Ruppert
BACKGROUND: Evidence on prehospital administration of the antifibrinolytic tranexamic acid (TXA) in civilian trauma populations is scarce. The aim was to study whether prehospital TXA use in trauma patients was associated with improved outcomes. METHODS: The prehospital database of the ADAC (General German Automobile Club) Air Rescue Service was linked with the TraumaRegister of the German Trauma Society to reidentify patients documented in both registries. Primarily admitted trauma patients (2012 until 2014) who were treated with TXA during the prehospital phase were matched with patients who had not received prehospital TXA, applying propensity score-based matching...
May 12, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/26095580/current-concepts-in-management-of-pain-in-children-in-the-emergency-department
#2
REVIEW
Baruch S Krauss, Lorenzo Calligaris, Steven M Green, Egidio Barbi
Pain is common in children presenting to emergency departments with episodic illnesses, acute injuries, and exacerbation of chronic disorders. We review recognition and assessment of pain in infants and children and discuss the manifestations of pain in children with chronic illness, recurrent pain syndromes, and cognitive impairment, including the difficulties of pain management in these patients. Non-pharmacological interventions, as adjuncts to pharmacological management for acute anxiety and pain, are described by age and development...
January 2, 2016: Lancet
https://www.readbyqxmd.com/read/26048068/a-randomized-controlled-trial-of-intravenous-haloperidol-vs-intravenous-metoclopramide-for-acute-migraine-therapy-in-the-emergency-department
#3
RANDOMIZED CONTROLLED TRIAL
Matthew E Gaffigan, David I Bruner, Courtney Wason, Amy Pritchard, Kenneth Frumkin
BACKGROUND: Emergency Department (ED) headache patients are commonly treated with neuroleptic antiemetics like metoclopramide. Haloperidol has been shown to be effective for migraine treatment. STUDY OBJECTIVE: Our study compared the use of metoclopramide vs. haloperidol to treat ED migraine patients. METHODS: A prospective, double-blinded, randomized control trial of 64 adults aged 18-50 years with migraine headache and no recognized risks for QT-prolongation...
September 2015: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/24363503/glucocorticosteroid-in-treatment-of-severe-pneumonia
#4
REVIEW
Felinda Ariani, Kaixiong Liu, Zhang Jing, Jieming Qu
Airway diseases such as pneumonia constitute a major health burden on a global scale; untreated pneumonia may develop to severe pneumonia and consequently lead to to fatal episodes of mortality and morbidity. The balance between inflammatory mediators is key for the outcome of the pulmonary infection; elimination of invading pathogen was marked by the release of cytokines and other inflammatory mediators from alveolar macrophages and glucocorticoid steroids (GCs) acting on the inflammatory component. Treatments of severe pneumonia with GCs have been developing for years with inconclusive results...
2013: Mediators of Inflammation
https://www.readbyqxmd.com/read/20811031/pharmacist-s-activities-on-a-trauma-response-team-in-the-emergency-department
#5
Asad E Patanwala, Daniel P Hays
PURPOSE: The interventions of a clinical pharmacist on an emergency department (ED) trauma response team were studied. METHODS: The study site was an academic, tertiary care hospital designated as a level 1 trauma center, with a clinical pharmacist present in the ED 40 hours per week. For a two-month period, interventions by the pharmacist in trauma cases were documented in an electronic quality-improvement database. RESULTS: A total of 304 interventions were recorded; the most common were dosage recommendations (60%) and provision of drug information (27%)...
September 15, 2010: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/16643581/haloperidol-in-the-acute-treatment-of-migraine-a-randomized-double-blind-placebo-controlled-study
#6
RANDOMIZED CONTROLLED TRIAL
Jari Honkaniemi, Suvi Liimatainen, Sirpa Rainesalo, Sari Sulavuori
OBJECTIVE: To assess the efficacy and safety of i.v. haloperidol in treatment of acute migraine headache in a double-blind, randomized, placebo-controlled study design. BACKGROUND: Neuroleptics are mainly used as antiemetics in acute migraine. In a previous open trial haloperidol was effective in relieving migraine pain. DESIGN: Patients were randomized into 2 groups receiving intravenously either 5 mg haloperidol in 500 mL of normal saline or 500 mL of normal saline alone...
May 2006: Headache
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