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Filiz Basralı, Günnur Koçer, Pınar Ülker Karadamar, Seher Nasırcılar Ülker, Leyla Satı, Nur Özen, Dilek Özyurt, Ümit Kemal Şentürk
The aim of this study was to assess the effect of oral magnesium supplementation (Mg-supp) on blood pressure (BP) and possible mechanism in nitric oxide synthase (NOS) inhibition-induced hypertension model. Hypertension and/or Mg-supp were created by N-nitro-l-arginine methyl ester (25 mg/kg/day by drinking water) and magnesium-oxide (0.8% by diet) for 6 weeks. Systolic BP was measured weekly by tail-cuff method. The effects of hypertension and/or Mg-supp in thoracic aorta and third branch of mesenteric artery constriction and relaxation responses were evaluated...
2015: Clinical and Experimental Hypertension: CHE
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