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Subclinical SCr increment

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4 papers 0 to 25 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
https://www.readbyqxmd.com/read/28874655/serum-neutrophil-gelatinase-associated-lipocalin-and-urinary-kidney-injury-molecule-1-as-potential-biomarkers-of-subclinical-nephrotoxicity-after-gadolinium-based-and-iodinated-based-contrast-media-exposure-in-pediatric-patients-with-normal-kidney-function
#1
Brankica Spasojević-Dimitrijeva, Jelena Kotur-Stevuljević, Milan Đukić, Dušan Paripović, Gordana Miloševski-Lomić, Vesna Spasojević-Kalimanovska, Polina Pavićević, Jadranka Mitrović, Mirjana Kostić
BACKGROUND New renal biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) show promise in early diagnosis of contrast media induced acute kidney injury (CI-AKI). The purpose of our study was to compare the subclinical nephrotoxicity (a condition without changes in standard renal biomarkers) of gadolinium-based contrast media (Gd-DTPA, gadopentetate dimeglumine) and iodinated-based contrast media (iopromide) in pediatric patients with normal kidney function...
September 6, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28849947/what-do-small-serum-creatinine-changes-tell-us-about-outcomes-after-acute-myocardial-infarction
#2
Johann Auer, Frederik H Verbrugge, Gudrun Lamm
Acute kidney injury (AKI), mostly defined as a rise in serum creatinine concentration of more than 0.5 mg/dl, is a common, serious, and potentially preventable complication of percutaneous coronary intervention and is associated with adverse outcomes including an increased risk of inhospital mortality. Recent data from the National Cardiovascular Data Registry/Cath-PCI registry including 985,737 consecutive patients undergoing percutaneous coronary intervention suggest that approximately 7% experienced AKI with a reported incidence of 3-19%...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28712521/subclinical-kidney-injury-in-children-receiving-nonsteroidal-anti-inflammatory-drugs-after-cardiac-surgery
#3
Edward Nehus, Ahmad Kaddourah, Michael Bennett, Olivia Pyles, Prasad Devarajan
OBJECTIVE: To investigate the association of nonsteroidal anti-inflammatory drug (NSAID) administration with urinary neutrophil gelatinase-associated lipocalin (NGAL) levels in children following cardiopulmonary bypass (CPB) who did not develop acute kidney injury (AKI). STUDY DESIGN: In this prospective observational study, urinary NGAL levels were investigated in 210 children who underwent cardiothoracic surgery requiring CPB. Children with clinical AKI (defined as an increase in serum creatinine ≥50% from baseline within 72 hours of CPB) were excluded from the analysis...
October 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/25728726/prognostic-significance-of-serum-creatinine-and-its-change-patterns-in-patients-with-acute-coronary-syndromes
#4
Giancarlo Marenzi, Angelo Cabiati, Nicola Cosentino, Emilio Assanelli, Valentina Milazzo, Mara Rubino, Gianfranco Lauri, Marco Morpurgo, Marco Moltrasio, Ivana Marana, Monica De Metrio, Alice Bonomi, Fabrizio Veglia, Antonio Bartorelli
BACKGROUND: In acute coronary syndromes (ACS), serum creatinine (sCr) levels have short- and long-term prognostic value. However, it is possible that repeated evaluations of sCr during hospitalization, rather than measuring sCr value at admission only, might improve risk assessment. We investigated the relationship between sCr baseline value, its changes, and in-hospital mortality in patients hospitalized with ACS. METHODS: In 2,756 ACS patients, sCr was measured at hospital admission and then daily, until discharge from coronary care unit...
March 2015: American Heart Journal
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