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Incidence and prevalence studies using EHR

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7 papers 0 to 25 followers Examples of studies measuring disease incidence or prevalence using EHR
Sally Wetten, Hamish Mohammed, Mandy Yung, Catherine H Mercer, Jackie A Cassell, Gwenda Hughes
OBJECTIVES: To determine the relative contribution of general practices (GPs) to the diagnosis of chlamydia and gonorrhoea in England and whether treatment complied with national guidelines. DESIGN: Analysis of longitudinal electronic health records in the Clinical Practice Research Datalink (CPRD) and national sexually transmitted infection (STI) surveillance databases, England, 2000-2011. SETTING: GPs, and community and specialist STI services...
2015: BMJ Open
Frances Rees, Michael Doherty, Matthew Grainge, Graham Davenport, Peter Lanyon, Weiya Zhang
OBJECTIVES: To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999-2012. METHODS: A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculated per 100 000 person-years and the prevalence was calculated per 100 000 people for the period 1999-2012 and stratified by year, age group, gender, region and ethnicity. Three definitions of SLE were explored: (1) systemic lupus, (2) a fully comprehensive definition of lupus including cutaneous only lupus and (3) requiring supporting evidence of SLE in the medical record...
January 2016: Annals of the Rheumatic Diseases
David Melzer, Behrooz Tavakoly, Rachel E Winder, Jane A H Masoli, William E Henley, Alessandro Ble, Suzanne H Richards
BACKGROUND: the oldest old (85+) pose complex medical challenges. Both underdiagnosis and overdiagnosis are claimed in this group. OBJECTIVE: to estimate diagnosis, prescribing and hospital admission prevalence from 2003/4 to 2011/12, to monitor trends in medicalisation. DESIGN AND SETTING: observational study of Clinical Practice Research Datalink (CPRD) electronic medical records from general practice populations (eligible; n = 27,109) with oversampling of the oldest old...
January 2015: Age and Ageing
Marie C Bradley, Nicola Motterlini, Shivani Padmanabhan, Caitriona Cahir, Tim Williams, Tom Fahey, Carmel M Hughes
BACKGROUND: Potentially inappropriate prescribing (PIP) in older people is associated with increases in morbidity, hospitalisation and mortality. The objective of this study was to estimate the prevalence of and factors associated with PIP, among those aged ≥70 years, in the United Kingdom, using a comprehensive set of prescribing indicators and comparing these to estimates obtained from a truncated set of the same indicators. METHODS: A retrospective cross-sectional study was carried out in the UK Clinical Practice Research Datalink (CPRD), in 2007...
2014: BMC Geriatrics
A C E Scowcroft, M R Cowie
OBJECTIVE: To investigate recent trends in the diagnosis and treatment of atrial fibrillation. METHODS: Time trend analysis in the UK Clinical Practice Research Datalink (CPRD -previously the GPRD), 2000-2012. RESULTS: The incidence of AF in men rose from 1.274 (1.271, 1.276) per 1 000 patient years in 2000 to 1.972 (1.969, 1.975) in 2012. In women, it rose from 1.209 (1.207, 1.211) to 1.609 (1.606, 1.611). 55847 patients with AF first diagnosed between 2000 and 2012 were included in the study...
February 1, 2014: International Journal of Cardiology
Alyshah Abdul Sultan, Laila J Tata, Matthew J Grainge, Joe West
BACKGROUND: Recent linkage between primary and secondary care data has provided valuable information for studying heath outcomes that may initially present in different health care settings. The aim of this study was therefore, twofold: to use linked primary and secondary care data to determine an optimum definition for estimating the incidence of first VTE in and around pregnancy; and secondly to conduct a systematic literature review of studies on perinatal VTE incidence with the purpose of comparing our estimates...
2013: PloS One
S H Holden, A H Barnett, J R Peters, S Jenkins-Jones, C D Poole, C L Morgan, C J Currie
AIMS: To characterize the incidence of type 2 diabetes in the UK over the previous 20 years; and determine if there has been an increase in people aged 40 years or less at diagnosis. METHODS: For this retrospective cohort study, patients newly diagnosed with type 2 diabetes between 1991 and 2010 were identified from the UK Clinical Practice Research Datalink (CPRD). Patient data were grouped into 5-year intervals by year of diagnosis and age at diagnosis. A standardized incidence ratio (SIR) was determined (1991-1995 = 100)...
September 2013: Diabetes, Obesity & Metabolism
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