Kirtipal Bhatia, Vardhmaan Jain, Michael J Hendrickson, Devika Aggarwal, Jose S Aguilar-Gallardo, Persio D Lopez, Bharat Narasimhan, Lingling Wu, Sameer Arora, Aditya Joshi, Matthew I Tomey, Kiran Mahmood, Arman Qamar, Edo Y Birati, Arieh Fox
Cardiogenic shock is associated with high short-term mortality. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used as a mechanical circulatory support strategy for patients with refractory cardiogenic shock. A drawback of this hemodynamic support strategy is increased left ventricular (LV) afterload, which is mitigated by concomitant use of Impella (extracorporeal membrane oxygenation with Impella [ECPELLA]). However, data regarding the benefits of this approach are limited. We conducted a systematic search of Medline, EMBASE, and Cochrane databases to identify studies including patients with cardiogenic shock reporting clinical outcomes with Impella plus VA-ECMO compared with VA-ECMO alone...
October 15, 2022: American Journal of Cardiology