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Schizophrenic

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19 papers 25 to 100 followers Phone use and preferences in safety net office of bup patients
https://www.readbyqxmd.com/read/27282305/auditory-hallucinations-in-the-population-what-do-they-mean-and-what-should-we-do-about-them
#1
EDITORIAL
I Kelleher
No abstract text is available yet for this article.
July 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/26714288/dopamine-receptor-d5-deficiency-results-in-a-selective-reduction-of-hippocampal-nmda-receptor-subunit-nr2b-expression-and-impaired-memory
#2
Rodrigo Moraga-Amaro, Hugo González, Valentina Ugalde, Juan Pablo Donoso-Ramos, Daisy Quintana-Donoso, Marcelo Lara, Bernardo Morales, Patricio Rojas, Rodrigo Pacheco, Jimmy Stehberg
Pharmacological evidence associates type I dopamine receptors, including subtypes D1 and D5, with learning and memory. Analyses using genetic approaches have determined the relative contribution of dopamine receptor D1 (D1R) in cognitive tasks. However, the lack of drugs that can discriminate between D1R and D5R has made the pharmacological distinction between the two receptors difficult. Here, we aimed to determine the role of D5R in learning and memory. In this study we tested D5R knockout mice and wild-type littermates in a battery of behavioral tests, including memory, attention, locomotion, anxiety and motivational evaluations...
April 2016: Neuropharmacology
https://www.readbyqxmd.com/read/26059249/social-skills-programmes-for-schizophrenia
#3
REVIEW
Muhammad Qutayba Almerie, Muhammad Okba Al Marhi, Muhammad Jawoosh, Mohamad Alsabbagh, Hosam E Matar, Nicola Maayan, Hanna Bergman
BACKGROUND: Social skills programmes (SSP) are treatment strategies aimed at enhancing the social performance and reducing the distress and difficulty experienced by people with a diagnosis of schizophrenia and can be incorporated as part of the rehabilitation package for people with schizophrenia. OBJECTIVES: The primary objective is to investigate the effects of social skills training programmes, compared to standard care, for people with schizophrenia. SEARCH METHODS: We searched the Cochrane Schizophrenia Group's Trials Register (November 2006 and December 2011) which is based on regular searches of CINAHL, BIOSIS, AMED, EMBASE, PubMed, MEDLINE, PsycINFO, and registries of clinical trials...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26059036/how-should-we-manage-anxiety-in-patients-with-schizophrenia
#4
REVIEW
Peter Bosanac, David Castle
OBJECTIVE: We aim to provide a selective clinically focused review of the epidemiology, aetiology and management of comorbid anxiety in people with schizophrenia. METHOD: The following databases were reviewed: PubMed, Medline and Embase. RESULTS: Anxiety is highly prevalent throughout course of schizophrenia, but is often not identified or its clinical significance is under-appreciated. Also, there is a paucity of rigorous data to support specific treatment guidelines for people with schizophrenia and concurrent anxiety disorders...
August 2015: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/26060820/the-effect-of-nicotine-dependence-on-psychopathology-in-patients-with-schizophrenia
#5
Anne Yee, Nik Nasyrah Bt Nek Mohamed, Aili Hanim Binti Hashim, Huai Seng Loh, Manveen Kaur Harbajan Singh, Chong Guan Ng, S T Jambunathan
INTRODUCTION: Our study aims to determine the prevalence of nicotine dependence and investigate the effect of nicotine dependence on psychopathology among schizophrenia patients. METHODS: A cross-sectional study was carried out in an outpatient psychiatric clinic at a general hospital in Malaysia. 180 recruited subjects were administered the Malay version of Mini International Neuropsychiatric Interview (MINI), the Positive and Negative Symptom Scale (PANSS), and the Malay version of Fagerstrom Test for Nicotine Dependence (FTND-M) questionnaires...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26062968/missing-link-in-community-psychiatry-when-a-patient-with-schizophrenia-was-expelled-from-her-home
#6
I-Ming Chen, Kevin Chien-Chang Wu, Yi-Ling Chien, Yu-Hsiang Chen, Sung-Tai Lee
Treatment and disposition of homeless patients with schizophrenia represent a great challenge in clinical practice. We report a case of this special population, and discuss the development of homelessness, the difficulty in disposition, their utilization of health services, and possible applications of mandatory community treatment in this group of patients. A 51-year-old homeless female was brought to an emergency department for left femur fracture caused by an assault. She was diagnosed with schizophrenia about 20 years ago but received little help from mental health services over the decades...
June 2015: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/26064055/predictors-of-quality-of-life-among-individuals-with-schizophrenia
#7
Sirijit Suttajit, Sutrak Pilakanta
PURPOSE: The study reported here aimed to evaluate both biological and psychosocial factors as predictors for quality of life as well as to examine the associations between the factors and quality of life in individuals with schizophrenia. METHODS: Eighty individuals with schizophrenia were recruited to the study. The Thai version of the World Health Organization Quality of Life-BREF was utilized to measure the quality of life. The five Marder subscales of the Positive and Negative Syndrome Scale were applied...
2015: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/26070547/the-subchronic-phencyclidine-rat-model-relevance-for-the-assessment-of-novel-therapeutics-for-cognitive-impairment-associated-with-schizophrenia
#8
REVIEW
Sanna K Janhunen, Heta Svärd, John Talpos, Gaurav Kumar, Thomas Steckler, Niels Plath, Linda Lerdrup, Trine Ruby, Marie Haman, Roger Wyler, Theresa M Ballard
RATIONALE: Current treatments for schizophrenia have modest, if any, efficacy on cognitive dysfunction, creating a need for novel therapies. Their development requires predictive animal models. The N-methyl-D-aspartate (NMDA) hypothesis of schizophrenia indicates the use of NMDA antagonists, like subchronic phencyclidine (scPCP) to model cognitive dysfunction in adult animals. OBJECTIVES: The objective of this study was to assess the scPCP model by (1) reviewing published findings of scPCP-induced neurochemical changes and effects on cognitive tasks in adult rats and (2) comparing findings from a multi-site study to determine scPCP effects on standard and touchscreen cognitive tasks...
November 2015: Psychopharmacology
https://www.readbyqxmd.com/read/26070758/neuropsychiatric-adverse-effects-of-amphetamine-and-methamphetamine
#9
REVIEW
Jaanus Harro
Administration of amphetamine and methamphetamine can elicit psychiatric adverse effects at acute administration, binge use, withdrawal, and chronic use. Most troublesome of these are psychotic states and aggressive behavior, but a large variety of undesirable changes in cognition and affect can be induced. Adverse effects occur more frequently with higher dosages and long-term use. They can subside over time but some persist long-term. Multiple alterations in the gray and white matter of the brain assessed as changes in tissue volume or metabolism, or at molecular level, have been associated with amphetamine and methamphetamine use and the psychiatric adverse effects, but further studies are required to clarify their causal role, specificity, and relationship with preceding states and traits and comorbidities...
2015: International Review of Neurobiology
https://www.readbyqxmd.com/read/26078684/quality-of-life-and-self-esteem-in-children-with-chronic-tic-disorder
#10
Selma Tural Hesapçıoğlu, Mustafa Kemal Tural, Sema Kandil
AIM: In this study, it was aimed to evaluate the quality of life and self-esteem in children and adolescents with Tourette syndrome (TS) and other chronic motor or vocal tic disorders in comparison with the control group. This is the first study examining the effects of quality of life and self-esteem on each other in chronic tic disorders. MATERIAL AND METHODS: Among 62 patients aged between 6 and 16 years who were diagnosed with chronic tic disorder according to the Diagnostic and Statistical Manual of Mental Disorders-IV, 57 patients who met the study inclusion criteria constituted the study group and 57 age- and gender-matched individuals constituted the control group (Ethics committee file number: 2009/69; ethics committee meeting number: 2009/14 (11...
December 2014: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/25977100/improving-psychiatrists-attitudes-towards-individuals-with-psychotic-disorders-and-co-occurring-substance-use-disorders
#11
Jonathan Avery, Erin Zerbo, Stephen Ross
No abstract text is available yet for this article.
June 2016: Academic Psychiatry
https://www.readbyqxmd.com/read/25918966/mobile-phone-use-patterns-and-preferences-in-safety-net-office-based-buprenorphine-patients
#12
Babak Tofighi, Ellie Grossman, Emily Buirkle, Jennifer McNeely, Marc Gourevitch, Joshua D Lee
BACKGROUND: Integrating mobile phone technologies in addiction treatment is of increasing importance and may optimize patient engagement with their care and enhance the delivery of existing treatment strategies. Few studies have evaluated mobile phone and text message (TM) use patterns in persons enrolled in addiction treatment, and none have assessed the use in safety net, office-based buprenorphine practices. METHODS: A 28-item, quantitative and qualitative semistructured survey was administered to opiate-dependent adults in an urban, publicly funded, office-based buprenorphine program...
May 2015: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/25711187/predisposition-to-schizophrenia-an-update-of-current-understanding
#13
Zhongxiang Du
Within the field of mental health, the concept of predisposition or that of being "at risk" has been properly addressed by Mrazek and Haggarty. This period prior to clear diagnosis of psychosis has been referred by several names like 'premorbid' phase, at-risk individuals, predisposed individuals, prodromal phase, etc. The premorbid phase is perhaps the most debated term in this list because this term suggests that the morbidity arises only in the overt illness phase. However, evidences arising from several different lines of observations suggest that this may not be the case...
September 2015: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/25531781/therapeutic-drug-monitoring-of-atypical-antipsychotic-drugs
#14
REVIEW
Milan Grundmann, Ivana Kacirova, Romana Urinovska
Schizophrenia is a severe psychiatric disorder often associated with cognitive impairment and affective, mainly depressive, symptoms. Antipsychotic medication is the primary intervention for stabilization of acute psychotic episodes and prevention of recurrences and relapses in patients with schizophrenia. Typical antipsychotics, the older class of antipsychotic agents, are currently used much less frequently than newer atypical antipsychotics. Therapeutic drug monitoring (TDM) of antipsychotic drugs is the specific method of clinical pharmacology, which involves measurement of drug serum concentrations followed by interpretation and good cooperation with the clinician...
December 2014: Acta Pharmaceutica
https://www.readbyqxmd.com/read/25512967/smoking-and-mental-illness-an-update-for-psychiatrists
#15
REVIEW
Colin P Mendelsohn, Dianne P Kirby, David J Castle
OBJECTIVE: We aimed to review research on smoking and mental illness and provide evidence-based guidelines for psychiatrists to help smoking patients quit. METHOD: We undertook a narrative review of the literature with a special focus on the Australian context. RESULTS: Although one in three people with mental illness smoke tobacco, smoking is often neglected in psychiatric practice. Smoking is a significant contributor to the health gap between people with mental illness and the general population...
February 2015: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/23591126/%C3%A2-meta-guidelines%C3%A2-for-the-management-of-patients-with-schizophrenia
#16
REVIEW
Stephen M Stahl, Debbi A Morrissette, Leslie Citrome, Stephen R Saklad, Michael A Cummings, Jonathan M Meyer, Jennifer A O' Day, Laura J Dardashti, Katherine D Warburton
Guidelines for treating various conditions can be helpful in setting practice standards, but the presence of several sets of guidelines from different countries, experts, and settings, written at different times, can also create confusion. Here we provide a "guideline of guidelines" for the treatment of schizophrenia, or "meta-guidelines, which not only reconcile the various existing standards but also update them to include the use of several newer agents, most of which were marketed following the publication of existing standards...
June 2013: CNS Spectrums
https://www.readbyqxmd.com/read/19698381/the-assessment-and-management-of-treatment-resistant-schizophrenia-in-perspective
#17
H Meltzer, H Hippius
Consensus was reached on the five following points: (1) "Treatment resistance" is a term which is widely used, but not adequately defined. In particular, definitions of "responders" and "non-responders" need to be more precise. (2) There is a need to extend the assessment of the results of treatment to include factors such as quality of life and the subjective evaluation by the patient and relatives. (3) Clozapine (Clozaril((R))/Leponex((R))) has become the standard for atypical antipsychotic drugs. The adjective "atypical" is not an exact descriptor...
1995: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/16172203/effectiveness-of-antipsychotic-drugs-in-patients-with-chronic-schizophrenia
#18
RANDOMIZED CONTROLLED TRIAL
Jeffrey A Lieberman, T Scott Stroup, Joseph P McEvoy, Marvin S Swartz, Robert A Rosenheck, Diana O Perkins, Richard S E Keefe, Sonia M Davis, Clarence E Davis, Barry D Lebowitz, Joanne Severe, John K Hsiao
BACKGROUND: The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents has been incompletely addressed, though newer agents are currently used far more commonly. We compared a first-generation antipsychotic, perphenazine, with several newer drugs in a double-blind study. METHODS: A total of 1493 patients with schizophrenia were recruited at 57 U.S. sites and randomly assigned to receive olanzapine (7.5 to 30 mg per day), perphenazine (8 to 32 mg per day), quetiapine (200 to 800 mg per day), or risperidone (1...
September 22, 2005: New England Journal of Medicine
https://www.readbyqxmd.com/read/10671383/late-onset-schizophrenia-and-very-late-onset-schizophrenia-like-psychosis-an-international-consensus-the-international-late-onset-schizophrenia-group
#19
REVIEW
R Howard, P V Rabins, M V Seeman, D V Jeste
OBJECTIVE: Although schizophrenia is generally regarded as an illness with onset in late adolescence or early adult life, a sizeable minority of patients first become ill in middle or old age. Inconsistencies in diagnostic systems and nomenclature, coupled with a tendency among most schizophrenia researchers to ascribe late-onset psychoses to organic factors, have led to such cases occupying an ambiguous position in relation to schizophrenia. Through systematic review of the literature and publication of a consensus statement from an international group of experts in the field, this article aims to clarify the positions of late-onset schizophrenia and very-late-onset schizophrenia-like psychosis...
February 2000: American Journal of Psychiatry
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