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BUMC-P Journal Club

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7 papers 25 to 100 followers
Jay L Koyner, Danielle L Davison, Ermira Brasha-Mitchell, Divya M Chalikonda, John M Arthur, Andrew D Shaw, James A Tumlin, Sharon A Trevino, Michael R Bennett, Paul L Kimmel, Michael G Seneff, Lakhmir S Chawla
Clinicians have access to limited tools that predict which patients with early AKI will progress to more severe stages. In early AKI, urine output after a furosemide stress test (FST), which involves intravenous administration of furosemide (1.0 or 1.5 mg/kg), can predict the development of stage 3 AKI. We measured several AKI biomarkers in our previously published cohort of 77 patients with early AKI who received an FST and evaluated the ability of FST urine output and biomarkers to predict the development of stage 3 AKI (n=25 [32...
August 2015: Journal of the American Society of Nephrology: JASN
Lakhmir S Chawla, Danielle L Davison, Ermira Brasha-Mitchell, Jay L Koyner, John M Arthur, Andrew D Shaw, James A Tumlin, Sharon A Trevino, Paul L Kimmel, Michael G Seneff
INTRODUCTION: In the setting of early acute kidney injury (AKI), no test has been shown to definitively predict the progression to more severe stages. METHODS: We investigated the ability of a furosemide stress test (FST) (one-time dose of 1.0 or 1.5 mg/kg depending on prior furosemide-exposure) to predict the development of AKIN Stage-III in 2 cohorts of critically ill subjects with early AKI. Cohort 1 was a retrospective cohort who received a FST in the setting of AKI in critically ill patients as part of Southern AKI Network...
September 20, 2013: Critical Care: the Official Journal of the Critical Care Forum
T Clark Powell, David G Warnock
No abstract text is available yet for this article.
August 2015: Journal of the American Society of Nephrology: JASN
Mario Siervo, Jose Lara, Shakir Chowdhury, Ammar Ashor, Clio Oggioni, John C Mathers
The Dietary Approach to Stop Hypertension (DASH) is recommended to lower blood pressure (BP), but its effects on cardiometabolic biomarkers are unclear. A systematic review and meta-analysis of randomised controlled trials (RCT) was conducted to determine the effects of the DASH diet on cardiovascular risk factors. Medline, Embase and Scopus databases were searched from inception to December 2013. Inclusion criteria were as follows: (1) DASH diet; (2) RCT; (3) risk factors including systolic and diastolic BP and glucose, HDL, LDL, TAG and total cholesterol concentrations; (4) control group...
January 14, 2015: British Journal of Nutrition
Kimberly A Gudzune, Ruchi S Doshi, Ambereen K Mehta, Zoobia W Chaudhry, David K Jacobs, Rachit M Vakil, Clare J Lee, Sara N Bleich, Jeanne M Clark
BACKGROUND: Commercial and proprietary weight-loss programs are popular obesity treatment options, but their efficacy is unclear. PURPOSE: To compare weight loss, adherence, and harms of commercial or proprietary weight-loss programs versus control/education (no intervention, printed materials only, health education curriculum, or <3 sessions with a provider) or behavioral counseling among overweight and obese adults. DATA SOURCES: MEDLINE and the Cochrane Database of Systematic Reviews from inception to November 2014; references identified by program staff...
April 7, 2015: Annals of Internal Medicine
Joanna A Leithead, Neil Rajoriya, Nadeem Tehami, James Hodson, Bridget K Gunson, Dhiraj Tripathi, James W Ferguson
OBJECTIVE: Recent data have suggested that non-selective β-blockers (NSBB) are associated with increased mortality in patients with cirrhosis and refractory ascites. However, other evidence implies that NSBB may be beneficial in this setting by reducing bacterial translocation. Our aim was to determine whether NSBB use was a risk factor for mortality in patients with end-stage chronic liver disease and ascites awaiting liver transplantation. DESIGN: This was a single-centre retrospective study of 322 patients with ascites listed January 2007 to July 2011...
July 2015: Gut
Thomas Sersté, Christian Melot, Claire Francoz, François Durand, Pierre-Emmanuel Rautou, Dominique Valla, Richard Moreau, Didier Lebrec
UNLABELLED: Beta-blockers may have a negative impact on survival in patients with cirrhosis and refractory ascites. The aim of this study was to evaluate the effect of the administration of beta-blockers on long-term survival in patients with cirrhosis and refractory ascites. We performed a single-center, observational, case-only, prospective study of patients with cirrhosis and refractory ascites who did or did not receive beta-blockers for the prevention of gastrointestinal bleeding; 151 patients were included...
September 2010: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
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