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Gastroenterology

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109 papers 100 to 500 followers
https://www.readbyqxmd.com/read/29194529/2017-infectious-diseases-society-of-america-clinical-practice-guidelines-for-the-diagnosis-and-management-of-infectious-diarrhea
#1
Andi L Shane, Rajal K Mody, John A Crump, Phillip I Tarr, Theodore S Steiner, Karen Kotloff, Joanne M Langley, Christine Wanke, Cirle Alcantara Warren, Allen C Cheng, Joseph Cantey, Larry K Pickering
These guidelines are intended for use by healthcare professionals who care for children and adults with suspected or confirmed infectious diarrhea. They are not intended to replace physician judgement regarding specific patients or clinical or public health situations. This document does not provide detailed recommendations on infection prevention and control aspects related to infectious diarrhea.
November 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29282496/management-of-complex-polyps-of-the-colon-and-rectum
#2
REVIEW
Fernando A Angarita, Adina E Feinberg, Stanley M Feinberg, Robert H Riddell, J Andrea McCart
PUPRPOSE: Benign polyps that are technically challenging and unsafe to remove via polypectomy are known as complex polyps. Concerns regarding safety and completeness of resection dictate they undergo advanced endoscopic techniques, such as endoscopic mucosal resection or surgery. We provide a comprehensive overview of complex polyps and current treatment options. METHODS: A review of the English literature was conducted to identifyarticles describing the management of complex polyps of the colon and rectum...
December 28, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28836158/associations-of-proton-pump-inhibitors-and-h2-receptor-antagonists-with-chronic-kidney-disease-a-meta-analysis
#3
REVIEW
Karn Wijarnpreecha, Charat Thongprayoon, Supavit Chesdachai, Panadeekarn Panjawatanana, Patompong Ungprasert, Wisit Cheungpasitporn
BACKGROUND/AIMS: The aim of this meta-analysis was to assess the risks of chronic kidney disease (CKD) and/or end-stage kidney disease (ESRD) in patients who are taking proton-pump inhibitors (PPIs) and/or H2 receptor antagonists (H2RAs). METHODS: Comprehensive literature review was conducted utilizing MEDLINE and EMBASE databases through April 2017 to identify all studies that investigated the risks of CKD or ESRD in patients taking PPIs/H2RAs versus those without PPIs/H2RAs...
October 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28024166/east-asian-perspective-on-the-interaction-between-proton-pump-inhibitors-and-clopidogrel
#4
REVIEW
Duowu Zou, Khean-Lee Goh
Both proton pump inhibitors (PPIs) and clopidogrel are widely prescribed in the Asia-Pacific population. PPIs are the mainstay therapeutic agents for prophylaxis against aspirin gastropathy and for acid-related disorders including gastroesophageal reflux disease. They are also co-prescribed with oral anticoagulant agents and with dual-antiplatelet therapy for the treatment and prevention of gastrointestinal bleeding. Clopidogrel belongs to the drug class of thienopyridines and is currently the most widely prescribed oral anticoagulant agent either alone or in combination with aspirin...
June 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28267445/abdominal-compression-by-waist-belt-aggravates-gastroesophageal-reflux-primarily-by-impairing-esophageal%C3%A2-clearance
#5
David R Mitchell, Mohammad H Derakhshan, Angela A Wirz, Stuart A Ballantyne, Kenneth E L McColl
BACKGROUND & AIMS: Central obesity promotes gastroesophageal reflux, which may be related to increased intra-abdominal pressure. We investigated the effect of increasing abdominal pressure by waist belt on reflux in patients with reflux disease. METHODS: We performed a prospective study of patients with esophagitis (n = 8) or Barrett's esophagus (n = 6); median age was 56 years and median body mass index was 26.8. Proton pump inhibitors were stopped at least 7 days before the study and H2 receptor antagonists were stopped for at least 24 hours before...
June 2017: Gastroenterology
https://www.readbyqxmd.com/read/28301676/deprescribing-versus-continuation-of-chronic-proton-pump-inhibitor-use-in-adults
#6
REVIEW
Taline A Boghossian, Farah Joy Rashid, Wade Thompson, Vivian Welch, Paul Moayyedi, Carlos Rojas-Fernandez, Kevin Pottie, Barbara Farrell
BACKGROUND: Proton pump inhibitors (PPIs) are a class of medications that reduce acid secretion and are used for treating many conditions such as gastroesophageal reflux disease (GERD), dyspepsia, reflux esophagitis, peptic ulcer disease, and hypersecretory conditions (e.g. Zollinger-Ellison syndrome), and as part of the eradication therapy for Helicobacter pylori bacteria. However, approximately 25% to 70% of people are prescribed a PPI inappropriately. Chronic PPI use without reassessment contributes to polypharmacy and puts people at risk of experiencing drug interactions and adverse events (e...
March 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29269313/no-significant-association-between-proton-pump-inhibitor-use-and-risk-of-stroke-after-adjustment-for-lifestyle-factors-and-indication
#7
Long H Nguyen, Paul Lochhead, Amit D Joshi, Yin Cao, Wenjie Ma, Hamed Khalili, Eric B Rimm, Kathryn M Rexrode, Andrew T Chan
BACKGROUND & AIMS: Proton pump inhibitors (PPI) are among the top 10 most-prescribed medications worldwide. We investigated the association between PPI use and ischemic stroke. METHODS: We collected data on 68,514 women (mean age 65±7 years) enrolled in the Nurses' Health Study (NHS) since 2000 and 28,989 men (mean age 69±8 years) in the Health Professionals Follow-up Study since 2004, without a history of prior stroke. We used Cox proportional hazards models to examine the association between risk of incident stroke and PPI use among participants...
December 18, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29053792/2017-infectious-diseases-society-of-america-clinical-practice-guidelines-for-the-diagnosis-and-management-of-infectious-diarrhea
#8
Andi L Shane, Rajal K Mody, John A Crump, Phillip I Tarr, Theodore S Steiner, Karen Kotloff, Joanne M Langley, Christine Wanke, Cirle Alcantara Warren, Allen C Cheng, Joseph Cantey, Larry K Pickering
These guidelines are intended for use by healthcare professionals who care for children and adults with suspected or confirmed infectious diarrhea. They are not intended to replace physician judgement regarding specific patients or clinical or public health situations. This document does not provide detailed recommendations on infection prevention and control aspects related to infectious diarrhea.
November 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29199146/constipation
#9
Hannah Herrington
No abstract text is available yet for this article.
November 30, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29206812/when-and-how-to-stop-surveillance-colonoscopy-in-older-adults-five-rules-of-thumb-for-practitioners
#10
Jennifer K Maratt, Audrey H Calderwood, Sameer D Saini
No abstract text is available yet for this article.
December 5, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29034088/emerging-dilemmas-in-the-diagnosis-and-management-of-gastroesophageal-reflux-disease
#11
REVIEW
Peter Kahrilas, Rena Yadlapati, Sabine Roman
Gastroesophageal reflux disease (GERD) is common, but less so than widely reported because of inconsistencies in definition. In clinical practice, the diagnosis is usually based on a symptom assessment without testing, and the extent of diagnostic testing pursued should be limited to that which guides management or which protects the patient from the risks of a potentially morbid treatment or an undetected early (or imminent) esophageal adenocarcinoma or which does both. When testing is pursued, upper gastrointestinal endoscopy is the most useful initial diagnostic test because it evaluates for the major potential morbidities (Barrett's, stricture, and cancer) associated with GERD and facilitates the identification of some alternative diagnostic possibilities such as eosinophilic esophagitis...
2017: F1000Research
https://www.readbyqxmd.com/read/28760445/coeliac-disease
#12
REVIEW
Benjamin Lebwohl, David S Sanders, Peter H R Green
Coeliac disease occurs in about 1% of people in most populations. Diagnosis rates are increasing, and this seems to be due to a true rise in incidence rather than increased awareness and detection. Coeliac disease develops in genetically susceptible individuals who, in response to unknown environmental factors, develop an immune response that is subsequently triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe malabsorption to minimally symptomatic or non-symptomatic presentations...
July 28, 2017: Lancet
https://www.readbyqxmd.com/read/28721213/diagnostic-approaches-and-treatment-of-eosinophilic-esophagitis-a-review-article
#13
REVIEW
Hossein Akhondi
Eosinophilic Esophagitis (EoE) is a condition that involves eosinophilic influx into the esophageal epithelium. It affects both children and adults; Adults present with dysphagia whereas children with vague abdominal complaints. The clinical symptoms as well as pathologic features of EoE and gastro esophageal reflux disease (GERD) are similar. Since eosinophilia in the esophagus is a non-specific finding, the clinical presentation in conjunction with endoscopic findings and pathology, is crucial in determining a differential diagnosis...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28728670/fifteen-years-of-ercp
#14
EDITORIAL
John Baillie
No abstract text is available yet for this article.
August 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28757269/proton-pump-inhibitors-and-chronic-kidney-disease-causation-or-another-false-alarm
#15
EDITORIAL
David J Bjorkman
No abstract text is available yet for this article.
July 27, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28827081/management-of-gastroesophageal-reflux-disease
#16
C Prakash Gyawali, Ronnie Fass
Management of GERD commonly starts with an empiric trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for patients without alarm symptoms. Optimization of therapy (improving compliance and timing of PPI doses), or increasing PPI dosage to twice daily in select circumstances, can reduce persistent symptoms. Patients with continued symptoms can be evaluated with endoscopy and tests of esophageal physiology, to better determine their disease phenotype and optimize treatment. Laparoscopic fundoplication, magnetic sphincter augmentation, and endoscopic therapies can benefit patients with well-characterized GERD...
August 4, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28797639/the-irony-of-long-term-acid-suppression
#17
EDITORIAL
Paul C Adams
No abstract text is available yet for this article.
September 2017: Gastroenterology
https://www.readbyqxmd.com/read/28692443/a-single-test-combining-blood-markers-and-elastography-is-more-accurate-than-other-fibrosis-tests-in-the-main-causes-of-chronic-liver-diseases
#18
Alexandra Ducancelle, Vincent Leroy, Julien Vergniol, Nathalie Sturm, Brigitte Le Bail, Jean Pierre Zarski, Eric Nguyen Khac, Dominique Salmon, Victor de Ledinghen, Paul Calès
BACKGROUND AND GOAL: International guidelines suggest combining a blood test and liver stiffness measurement (LSM) to stage liver fibrosis in chronic hepatitis C (CHC) and non-alcoholic fatty liver disease (NAFLD). Therefore, we compared the accuracies of these tests between the main etiologies of chronic liver diseases. STUDY: Overall, 1968 patients were included in 5 etiologies: CHC: 698, chronic hepatitis B: 152, human immunodeficiency virus/CHC: 628, NAFLD: 225, and alcoholic liver disease (ALD): 265...
August 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28684104/acid-base-disorders-in-liver-disease
#19
REVIEW
Bernhard Scheiner, Gregor Lindner, Thomas Reiberger, Bruno Schneeweiss, Michael Trauner, Christian Zauner, Georg-Christian Funk
Alongside the kidneys and lungs, the liver has been recognised as an important regulator of acid-base homeostasis. While respiratory alkalosis is the most common acid-base disorder in chronic liver disease, various complex metabolic acid-base disorders may occur with liver dysfunction. While the standard variables of acid-base equilibrium, such as pH and overall base excess, often fail to unmask the underlying cause of acid-base disorders, the physical-chemical acid-base model provides a more in-depth pathophysiological assessment for clinical judgement of acid-base disorders, in patients with liver diseases...
November 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28786407/strategies-to-combat-physician-burnout-in-gastroenterology
#20
Joseph C Anderson, Sheryl Pfeil, Christina Surawicz
No abstract text is available yet for this article.
September 2017: American Journal of Gastroenterology
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