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Gout

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3 papers 0 to 25 followers
https://www.readbyqxmd.com/read/27457514/2016-updated-eular-evidence-based-recommendations-for-the-management-of-gout
#1
P Richette, M Doherty, E Pascual, V Barskova, F Becce, J Castañeda-Sanabria, M Coyfish, S Guillo, T L Jansen, H Janssens, F Lioté, C Mallen, G Nuki, F Perez-Ruiz, J Pimentao, L Punzi, T Pywell, A So, A K Tausche, T Uhlig, J Zavada, W Zhang, F Tubach, T Bardin
BACKGROUND: New drugs and new evidence concerning the use of established treatments have become available since the publication of the first European League Against Rheumatism (EULAR) recommendations for the management of gout, in 2006. This situation has prompted a systematic review and update of the 2006 recommendations. METHODS: The EULAR task force consisted of 15 rheumatologists, 1 radiologist, 2 general practitioners, 1 research fellow, 2 patients and 3 experts in epidemiology/methodology from 12 European countries...
July 25, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/22069122/an-update-on-the-pathology-and-clinical-management-of-gouty-arthritis
#2
REVIEW
Emilio B Gonzalez
Gouty arthritis is an inflammatory condition associated with debilitating clinical symptoms, functional impairments, and a substantial impact on quality of life. This condition is initially triggered by the deposition of monosodium urate crystals into the joint space. This causes an inflammatory cascade resulting in the secretion of several proinflammatory cytokines and neutrophil recruitment into the joint. While generally effective, currently available agents are associated with a number of adverse events and contraindications that complicate their use...
January 2012: Clinical Rheumatology
https://www.readbyqxmd.com/read/25364883/cost-effectiveness-of-allopurinol-and-febuxostat-for-the-management-of-gout
#3
Eric Jutkowitz, Hyon K Choi, Laura T Pizzi, Karen M Kuntz
BACKGROUND: Gout is the most common inflammatory arthritis in the United States. OBJECTIVE: To evaluate the cost-effectiveness of urate-lowering treatment strategies for the management of gout. DESIGN: Markov model. DATA SOURCES: Published literature and expert opinion. TARGET POPULATION: Patients for whom allopurinol or febuxostat is a suitable initial urate-lowering treatment. TIME HORIZON: Lifetime...
November 4, 2014: Annals of Internal Medicine
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