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111 papers 0 to 25 followers
https://www.readbyqxmd.com/read/27475817/operative-correction-of-abdominal-rectus-diastasis-ard-reduces-pain-and-improves-abdominal-wall-muscle-strength-a-randomized-prospective-trial-comparing-retromuscular-mesh-repair-to-double-row-self-retaining-sutures
#1
Peter Emanuelsson, Ulf Gunnarsson, Ursula Dahlstrand, Karin Strigård, Birgit Stark
BACKGROUND: The primary aim of this prospective, randomized, clinical, 2-armed trial was to evaluate the risk for recurrence using 2 different operative techniques for repair of abdominal rectus diastasis. Secondary aims were comparison of pain, abdominal muscle strength, and quality of life and to compare those outcomes to a control group receiving physical training only. METHODS: Eighty-six patients were enrolled. Twenty-nine patients were allocated to retromuscular polypropylene mesh and 27 to double-row plication with Quill technology...
November 2016: Surgery
https://www.readbyqxmd.com/read/26453003/ketamine-attenuates-high-mobility-group-box-1-induced-inflammatory-responses-in%C3%A2-endothelial-cells
#2
Zhaohui Liu, Zhengping Wang, Guangwei Han, Lina Huang, Jihong Jiang, Shitong Li
BACKGROUND: High mobility group box-1 (HMGB1) acts as an inflammatory mediator and has been implicated in pathophysiological damage of vascular inflammatory diseases. Ketamine, an anesthetic agent with sedative and analgesic properties, has been shown to have potent anti-inflammatory effects in a variety of models of systemic inflammation. However, the effects of ketamine on HMGB1-mediated proinflammatory responses have not been fully investigated. In the present study, we investigated the effects of ketamine on HMGB1-activated endothelial cells and explored the underlying mechanisms...
February 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/26400843/to-roux-or-not-to-roux-a-comparison-between-roux-en-y-and-billroth-ii-reconstruction-following-partial-gastrectomy-for-gastric-cancer
#3
Thuy B Tran, David J Worhunsky, Malcolm H Squires, Linda X Jin, Gaya Spolverato, Konstantinos I Votanopoulos, Clifford S Cho, Sharon M Weber, Carl Schmidt, Edward A Levine, Mark Bloomston, Ryan C Fields, Timothy M Pawlik, Shishir K Maithel, Jeffrey A Norton, George A Poultsides
BACKGROUND: Although the extent of resection frequently dictates the method of reconstruction following distal subtotal gastrectomy, it is unclear whether Roux-en-Y gastrojejunostomy compared with Billroth II gastrojejunostomy is associated with superior perioperative outcomes. METHODS: Patients who underwent resection for gastric cancer with Roux-en-Y or Billroth II reconstruction between 2000 and 2012 in seven academic institutions (US Gastric Cancer Collaborative) were identified...
July 2016: Gastric Cancer
https://www.readbyqxmd.com/read/26033038/cyst-gastrostomy-and-necrosectomy-for-the-management-of-sterile-walled-off-pancreatic-necrosis-a-comparison-of-minimally-invasive-surgical-and-endoscopic-outcomes-at-a-high-volume-pancreatic-center
#4
COMPARATIVE STUDY
Mohammad Khreiss, Mazen Zenati, Amber Clifford, Kenneth K Lee, Melissa E Hogg, Adam Slivka, Jennifer Chennat, Andres Gelrud, Herbert J Zeh, Georgios I Papachristou, Amer H Zureikat
INTRODUCTION: Walled-off pancreatic necrosis (WON) is a sequela of acute necrotizing pancreatitis in 15-40% of cases. We sought to compare the outcomes of minimally invasive surgical and endoscopic cyst gastrostomy (CG) and necrosectomy for the management for sterile WON at a tertiary care high-volume pancreas center. METHOD: This is a retrospective review of patients who underwent minimally invasive surgical or endoscopic CG and necrosectomy for clinically sterile WON between 2008 and 2013...
August 2015: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/26032832/evaluation-of-the-fukuoka-consensus-guidelines-for-intraductal-papillary-mucinous-neoplasms-of-the-pancreas-results-from-a-systematic-review-of-1-382-surgically-resected-patients
#5
REVIEW
Brian K P Goh, Zhimin Lin, Damien M Y Tan, Choon-Hua Thng, Christopher J L Khor, Tony K H Lim, London L P J Ooi, Alexander Y F Chung
BACKGROUND: International consensus guidelines to guide management of intraductal papillary mucinous neoplasms (IPMN) were revised in Fukuoka and published in 2012. However, despite widespread acceptance of the Fukuoka Consensus Guidelines (FCG), the utility of these guidelines have not been well-validated. This systematic review was performed to evaluate the clinical utility of the FCG. DESIGN: A computerized search of the PubMed and Scopus databases was performed to identify all studies evaluating the utility of the FCG in surgically resected IPMN...
November 2015: Surgery
https://www.readbyqxmd.com/read/23070690/recent-progress-in-understanding-diagnosing-and-treating-hepatocellular-carcinoma
#6
REVIEW
Mary Maluccio, Anne Covey
Hepatocellular carcinoma (HCC) is one of the few cancers in which a continued increase in incidence has been observed over several years. As such, there has been a focus on safe and accurate diagnosis and the development of treatment algorithms that take into consideration the unique complexities of this patient population. In the past decade, there have been improvements in nonsurgical treatment platforms and better standardization with respect to the diagnosis and patient eligibility for liver transplant...
November 2012: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/25789941/surgical-management-of-patients-with-colorectal-cancer-and-simultaneous-liver-and-lung-metastases
#7
MULTICENTER STUDY
A Andres, G Mentha, R Adam, E Gerstel, O G Skipenko, E Barroso, S Lopez-Ben, C Hubert, P E Majno, C Toso
BACKGROUND: The management of patients with colorectal cancer and simultaneously diagnosed liver and lung metastases (SLLM) remains controversial. METHODS: The LiverMetSurvey registry was interrogated for patients treated between 2000 and 2012 to assess outcomes after resection of SLLM, and the factors associated with survival. SLLM was defined as liver and lung metastases diagnosed 3 months or less apart. Survival was compared between patients with resected isolated liver metastases (group 1, control), those with resected liver and lung metastases (group 2), and patients with resected liver metastases and unresected (or unresectable) lung metastases (group 3)...
May 2015: British Journal of Surgery
https://www.readbyqxmd.com/read/25472029/-true-duct-to-mucosa-pancreaticojejunostomy-with-secure-eversion-of-the-enteric-mucosa-in-whipple-operation
#8
COMPARATIVE STUDY
Dionissios D Karavias, Dimitrios D Karavias, Ioannis G Chaveles, Stavros K Kakkos, Nicolaos A Katsiakis, Ioannis C Maroulis
BACKGROUND: Postoperative pancreatic fistula (POPF) due to anastomotic leak is often associated with significant morbidity and mortality. The aim of this study was to present an improved anastomotic technique for Whipple operation, which we call "true" duct-to-mucosa anastomosis (DMA)-pancreaticojejunostomy. METHODS: A novel enteric mucosal eversion at the point of the jejunostomy is constructed prior to the anastomosis with the pancreatic duct in order to enhance sealing...
March 2015: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/25712200/validation-and-improvement-of-a-proposed-scoring-system-to-detect-retained-common-bile-duct-stones-in-gallstone-pancreatitis
#9
COMPARATIVE STUDY
Jingjing L Sherman, Emily W Shi, Nalin E Ranasinghe, Muthu T Sivasankaran, Jake G Prigoff, Celia M Divino
BACKGROUND: In 2009, a study from our institution used retrospective data and multivariate analysis to identify 5 quantitative variables and their cutoffs that have a positive predictive value (PPV) for common bile duct (CBD) stones in gallstone pancreatitis. They also proposed a management protocol based on the scoring system. This prospective study sought to validate that scoring system. METHODS: From October 2009 to August 2013, patients with gallstone pancreatitis were enrolled in the study...
June 2015: Surgery
https://www.readbyqxmd.com/read/25711855/hospital-teaching-status-and-volume-related-to-mortality-after-pancreatic-cancer-surgery-in-a-national-cohort
#10
MULTICENTER STUDY
M Derogar, J Blomberg, O Sadr-Azodi
BACKGROUND: The association between hospital teaching status and mortality after pancreatic resection is not well explored. Although hospital volume is related to short-term mortality, the effect on long-term survival needs investigation, taking into account hospital teaching status and selective referral patterns. METHODS: This was a nationwide retrospective register-based cohort study of patients undergoing pancreatic resection between 1990 and 2010. Follow-up for survival was carried out until 31 December 2011...
April 2015: British Journal of Surgery
https://www.readbyqxmd.com/read/25786743/octreoscan-versus-fdg-pet-for-neuroendocrine-tumor-staging-a-biological-approach
#11
COMPARATIVE STUDY
Malcolm H Squires, N Volkan Adsay, David M Schuster, Maria C Russell, Kenneth Cardona, Keith A Delman, Joshua H Winer, Deniz Altinel, Juan M Sarmiento, Bassel El-Rayes, Natalyn Hawk, Charles A Staley, Shishir K Maithel, David A Kooby
BACKGROUND: Clinicians may order Octreoscan or positron emission tomography (PET) scan for staging patients with neuroendocrine tumors (NETs). (111)In-Octreoscan (Octreoscan) identifies tumors by radiolabeled targeting of somatostatin receptors, while 18F-fluorodeoxyglucose-positron emission tomography ((18)FDG-PET) measures differential tissue glucose transport. We assessed the sensitivity of both nuclear imaging modalities with pathologic correlation to define the best initial choice for NET staging after standard cross-sectional imaging...
July 2015: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/24700300/morbidity-and-mortality-associated-with-gastrectomy-for-gastric-cancer
#12
MULTICENTER STUDY
Wesley A Papenfuss, Moshim Kukar, Jacqueline Oxenberg, Kristopher Attwood, Steven Nurkin, Usha Malhotra, Neal W Wilkinson
BACKGROUND: Surgery alone is often inadequate for advanced-stage gastric cancer. Surgical complications may delay adjuvant therapy. Understanding these complications is needed for multidisciplinary planning. MATERIAL AND METHODS: The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database was queried for patients who underwent gastrectomy for malignancy (ICD-9 code 151.x) from 2005 to 2010. Thirty-day mortality and morbidity were evaluated...
September 2014: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/25190126/surgical-treatment-of-adenocarcinomas-of-the-gastro-esophageal-junction
#13
K Parry, L Haverkamp, R C G Bruijnen, P D Siersema, J P Ruurda, R van Hillegersberg
BACKGROUND: Patients with adenocarcinoma of the gastro-esophageal junction (GEJ) may undergo either esophagectomy or gastrectomy. The aim of this study was to evaluate the outcome of surgical therapy with regard to postoperative outcome and survival in patients with Siewert type II tumors. METHODS: A prospective database of 266 consecutive patients with surgically resectable GEJ adenocarcinomas from 2003 to 2013 was analyzed. The surgical approach was based on preoperative imaging and intraoperative findings...
February 2015: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/24000011/routine-abdominal-drainage-versus-no-abdominal-drainage-for-uncomplicated-laparoscopic-cholecystectomy
#14
REVIEW
Kurinchi Selvan Gurusamy, Rahul Koti, Brian R Davidson
BACKGROUND: Laparoscopic cholecystectomy is the main method of treatment of symptomatic gallstones. Drains are used after laparoscopic cholecystectomy to prevent abdominal collections. However, drain use may increase infective complications and delay discharge. OBJECTIVES: The aim is to assess the benefits and harms of routine abdominal drainage in uncomplicated laparoscopic cholecystectomy. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and Science Citation Index Expanded until February 2013...
2013: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/22365521/updates-on-the-management-of-gastrointestinal-stromal-tumors
#15
Zubin M Bamboat, Ronald P Dematteo
Despite being the most common sarcoma of the gastrointestinal tract, gastrointestinal stromal tumor (GIST) has been widely recognized as a unique entity for just over a decade. The advent of tyrosine kinase inhibitors has revolutionized the diagnosis and treatment of GIST. Although surgery remains the only chance for cure, multimodal treatment that includes molecular therapy continues to develop. Optimal management of GIST requires careful radiographic, pathologic, medical, and surgical care, emphasizing the need for a multidisciplinary approach...
April 2012: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/23835731/molecular-pathogenesis-of-hepatic-adenomas-and-its-implications-for-surgical-management
#16
REVIEW
Siong-Seng Liau, M Saeed Qureshi, Raaj Praseedom, Emmanuel Huguet
INTRODUCTION: Hepatic adenomas (HAs) are benign tumors of the liver, which can be solitary or multiple, and have a definite risk of malignant degeneration. DISCUSSION: The pathogenesis and natural history of this disease entity were previously unknown. Recent research into the molecular pathogenesis of this condition has provided evidence for the malignant transformation of some of these adenomas. In the current article, we discuss the current evidence on the molecular biology underlying malignant transformation of hepatic adenomas and the implications for the surgical management of this disease...
October 2013: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/22560405/implications-of-clinical-risk-score-to-predict-outcomes-of-liver-confined-metastasis-of-colorectal-cancer
#17
Sang Joon Shin, Joong Bae Ahn, Jin Sub Choi, Gi-Hong Choi, Kang Young Lee, Seung Hyuk Baik, Byung Soh Min, Hyuk Hur, Jae Kyung Roh, Nam Kyu Kim
OBJECTIVE/BACKGROUND: We investigated the usefulness of a clinical risk scoring system (CRS) for guiding management and defining prognosis for patients with colorectal liver met"astases (CLM). METHOD: We retrospectively analyzed data about the correlation between outcomes and Fong's CRS from 1989 to 2010 for patients treated for CLM at the Severance Hospital. RESULTS: Of 566 patients, 232 received adjuvant treatment after liver resection. Of these patients, 185 (81%) had a low CRS (0-2) and 47 (19%) had a high CRS (3-5)...
September 2012: Surgical Oncology
https://www.readbyqxmd.com/read/23636978/a-modified-technique-of-end-to-end-pancreaticojejunostomy-with-transpancreatic-interlocking-mattress-sutures
#18
Min Wang, Feng Zhu, Xin Wang, Rui Tian, Chengjian Shi, Ming Shen, Meng Xu, Juan Han, Niannian Luo, Renyi Qin
BACKGROUND: Postoperative pancreatic fistula (POPF) represents the most important cause of morbidity after pancreaticoduodenectomy (PD) and contributes to prolonged hospitalization and increased mortality rates. This study presents a new technique, which involves end-to-end pancreaticojejunostomy with transpancreatic interlocking mattress sutures, and evaluates its safety and reliability. METHODS: From January 2011 to May 2012, 79 patients with periampullary malignancies underwent PD by using this modified technique, and the morbidity and mortality rates were calculated...
June 2013: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25791792/prognostic-relevance-of-p53-overexpression-in-gastrointestinal-stromal-tumors-of-the-small-intestine-potential-implication-for-adjuvant-treatment-with-imatinib
#19
Changhoon Yoo, Young Wha Koh, Young Soo Park, Min-Hee Ryu, Baek-Yeol Ryoo, Hye Jin Park, Jeong Hwan Yook, Byung Sik Kim, Yoon-Koo Kang
PURPOSE: Although genetic p53 aberrations are correlated with the prognosis of various types of cancer, their prognostic relevance is currently unclear in patients with gastrointestinal stromal tumors (GISTs) of the small intestine. METHODS: Between 1994 and 2008, 113 patients with resected localized GISTs of the small intestine were included in this analysis. Patients who received pre- and/or postoperative chemotherapy were excluded. p53 overexpression was assessed by immunohistochemical staining and defined as expression in >10 % of tumor cells...
December 2015: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/25023547/surgical-approaches-to-advanced-gallbladder-cancer-a-40-year-single-institution-study-of-prognostic-factors-and-resectability
#20
Ryota Higuchi, Takehiro Ota, Tatsuo Araida, Hideki Kajiyama, Takehisa Yazawa, Toru Furukawa, Tatsuya Yoshikawa, Ken Takasaki, Masakazu Yamamoto
PURPOSE: The aim was to evaluate prognostic factors and factors associated with the resectability of advanced gallbladder cancer (GBC). METHODS: This was a single-institution retrospective review of 274 consecutive surgically-treated cases of advanced GBC (excluding incidental GBC and early GBC). Univariate and multivariate analysis were performed to assess prognostic variables. R0 resection and survival rates were investigated for each local extension factor. RESULTS: Long-term survival was uncommon among patients with multiple liver metastases (H2-3: n = 22; 2-year survival, 0 %), dissemination (P1-3: n = 16; 3-year survival, 0 %), invasion through the hepatoduodenal ligament (Binf3: n = 45; 5-year survival, 4...
December 2014: Annals of Surgical Oncology
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